A multicenter study on chronic cough in children: Burden and etiologies based on a standardized management pathway

Background: While the burden of chronic cough in children has been documented, etiologic factors across multiple settings and age have not been described. In children with chronic cough, we aimed (1) to evaluate the burden and etiologies using a standar

Irukandji sydrome in the Torres Strait: a series of 8 cases

Objective: To review the presentations of a series of patients with suspected Irukandji syndrome in the Torres Strait, where the syndrome has hitherto been unknown or undocumented, in order to identify at-risk groups and improve the management of this condition in the region.\ud \ud Methods: A mixed retrospective-prospective review of eight cases of patients with suspected Irukandji syndrome in the Torres Strait, with a focus on the differences between the clinical presentations and patient outcomes.\ud \ud Results: Irukandji syndrome is the most likely explanation, based on current knowledge, of this series of marine envenomation syndromes in the Torres Strait. The syndrome appears to be more common in the monsoon season and young, Torres Strait Islander males likely represent a high-risk group in the region.\ud \ud Conclusions: The Torres Strait can be added to the growing list of regions where Irukandji syndrome has been documented. The clinical picture, including time to onset of symptoms, constellation of symptoms and signs, analgesic requirement and time to recovery, can differ markedly between patients. There is a need for health promotion and education of health staff and the public regarding the risks, symptoms and signs of this condition. There is also a clear need for the use of case definitions and standardised management approaches for Irukandji syndrome, while the health community awaits the results of ongoing research into the pathophysiology and improved treatments for this interesting but dangerous tropical marine envenomation syndrome

Модель деформирования поры в оболочке эритроцита

BACKGROUND: Chronic cough is associated with poor quality of life and may signify a serious underlying disease. Differentiating nonspecific cough (when watchful waiting can be safely undertaken) from specific cough (treatment and further investigations are beneficial) would be clinically useful. In 326 children, we aimed to (1) determine how well cough pointers (used in guidelines) differentiate specific from nonspecific cough and (2) describe the clinical profile of children whose cough resolved without medications (spontaneous resolution)

A multicenter study on chronic cough in childre: burden and etiologies based on a standardized management pathway

Background: While the burden of chronic cough in children has been documented, etiologic factors across multiple settings and age have not been described. In children with chronic cough, we aimed (1) to evaluate the burden and etiologies using a standard management pathway in various settings, and (2) to determine the influence of age and setting on disease burden and etiologies and etiology on disease burden. We hypothesized that the etiology, but not the burden, of chronic cough in children is dependent on the clinical setting and age