Dermoscopic clues to diagnose acantholytic dyskeratosis

A 61-year-old man presented with multiple small, reddish, eroded papules located on his chest (Figure 1A). Histopathologic examination revealed the typical findings of Grover\u2019s disease

Age, gender, and topography influence the clinical and dermoscopic appearance of lentigo maligna

BACKGROUND: Little is known about the frequency of clinical and dermoscopic patterns of lentigo maligna (LM) in relation to specific anatomic subsites and patients characteristics. OBJECTIVE: We sought to assess the frequency of clinical and dermoscopic features of LM and to correlate them to specific anatomic subsites, and patients' age and gender. METHODS: This was a retrospective analysis of clinical and dermoscopic images of a series of consecutive, histopathologically diagnosed, facial and extrafacial LM. RESULTS: A total of 201 cases from 200 patients (mean age 69.51 \ub1 12.26 years) including 120 women were collected. Most cases were located on the face (n = 192, 95.5%). In 102 cases, LM presented as clinically solitary facial macule (s/LM), whereas it was associated with multiple surrounding freckles in the remaining cases. s/LM were significantly smaller (10 mm; P = .020) and associated with younger age compared with LM associated with multiple surrounding freckles (mean age 67.73 \ub1 12.68 years vs 71.34 \ub1 11.59 years, respectively; P = .036). Dermoscopically, gray color irrespective of a specific pattern was the most prevalent finding seen in 178 (88.6%) cases. LIMITATIONS: This was a retrospective study. CONCLUSIONS: The knowledge about patient age, patient gender, and site-related clinical features of LM associated with gray color upon dermoscopy may enhance the clinical recognition of LM

GIANT CONGENITAL NEVUS – CASE REPORT

Congenital nevomelanocitic nevi (CN) are benign melanocitic proliferations present at birth. The incidence of giant CN is 0,002% in the newborns. The paper presents the case of a 20-year old female with giant CN on the skin of the right hand. Dermoscopy is very useful in differential diagnosis of pigmented skin lesions. Dermoscopic characteristics of CN are the presence of uniform globules - the "pebble stone" pattern. Giant CN overtaking more than 5% of the skin has an increased risk of malignant melanoma. Possible therapy modalities for CN are: excision with grafts, dermabrasion, curettage and laser. Periodical check-ups are necessary

Dermoscopy of clear cell acanthoma

A 97-year-old man presented with a 1-year history of a 1.5-cm asymptomatic erythematous nodule on his left leg (Fig 1). Two smaller erythematous lesions appeared more recently in close vicinity to the first lesion. Personal and family history for skin cancer was negative

The importance of gray color as a dermoscopic clue in facial pigmented lesion evaluation: a case report

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Successful treatment of two invasive squamous cell carcinomas with topical 5% imiquimod cream in elderly patients

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Problematic lesions in the elderly

As the population continues to age, clinicians and dermatologists are increasingly faced with geriatric patients presenting with a range of dermatologic manifestations, including benign and malignant skin tumors. Knowledge of epidemiologic and morphologic features, including dermoscopy of common and benign melanocytic and nonmelanocytic skin tumors, provides the basis for a better understanding and management of problematic skin tumors in this age group. This article provides an overview of common and problematic skin lesions in elderly patients and addresses epidemiologic, clinical, and dermoscopic clues that aid the differential diagnosis and management of challenging skin lesions

Dermoscopy of cutaneous sarcoidosis

The clinical variability of cutaneous sarcoidosis (CS) often makes its correct diagnosis challenging. Although traditionally employed for the diagnosis of skin tumors, during the past years dermoscopy also gained increasing interest as an aid in the clinical diagnosis of inflammatory and infectious skin manifestations in general dermatology

Twenty nevi on the arms: a simple rule to identify patients younger than 50 years of age at higher risk for melanoma

13Patients with a high total nevus count (TNC) merit a total-body examination, but a simple strategy to identify these high-risk individuals is essentially missing. The aim of this study was to investigate the correlation between the number of melanocytic nevi on both arms and the TNC, and to evaluate patient variables that may have an effect on this association. In this multicenter, cross-sectional study, 2175 patients were examined and the mean number of arm nevi in relation to TNC was calculated. A mean value of fewer than 10 arm nevi was found in patients with TNC lower than 51 and a mean value of greater than 19 arm nevi was scored in patients with TNC greater than 50. These values remained unchanged after adjustment for various patient variables. In relation to TNC greater than 50, the presence of 20 or more arm nevi had specificity and negative predictive values of 95.2 and 89.6%, respectively. The sensitivity was 65.5% in patients younger than 50 years of age and 37.5% in the older age group. The number of arm nevi was significantly higher in individuals with a history of melanoma and in those with a melanoma detected during the study period. The presence of 20 or more nevi on the arms is an independent predictor of a high TNC and risk of melanoma. This sign thus represents a simple and rapid screening tool for either the primary care physician or the dermatologist to help identify high-risk patients.nonenoneArgenziano, Giuseppe; Giacomel, Jason; Zalaudek, Iris; Apalla, Zoe; Blum, Andreas; De Simone, Paola; Lallas, Aimilios; Longo, Caterina; Moscarella, Elvira; Tiodorovic-Zivkovic, Danica; Tiodorovic, Jelica; Jovanovic, Dragan L; Kittler, HaraldArgenziano, Giuseppe; Giacomel, Jason; Zalaudek, Iris; Apalla, Zoe; Blum, Andreas; De Simone, Paola; Lallas, Aimilios; Longo, Caterina; Moscarella, Elvira; Tiodorovic-Zivkovic, Danica; Tiodorovic, Jelica; Jovanovic, Dragan L; Kittler, Haral