A simple and efficient
Ru­(II)-catalyzed transfer hydro-dehalogenation
of organic halides using 2-propanol solvent as the hydride source
was reported. This methodology is applicable for hydro-dehalogenation
of a variety of aromatic halides and α-haloesters and amides
without additional ligand, and quantitative yields were achieved in
many cases. The potential synthetic application of this method was
demonstrated by efficient gram-scale transformation with catalyst
loading as low as 0.5 mol %

Jiajia Chen (187079)