868 research outputs found

    Feasibility and reliability analysis of LCC DC grids and LCC/VSC hybrid DC grids

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    Power system interconnections using high-voltage direct-current (HVDC) technologies between different areas can be an effective solution to enhance system efficiency and reliability. Particularly, the multi-terminal DC grids, that could balance and ensure resource adequacy, increase asset utilization and reduce costs. In this paper, the technical feasibility of building DC grids using the line commutated converter based (LCC) and voltage source converter based (VSC) HVDC technologies are discussed. Apart from presenting the technical challenges of building LCC DC grids and LCC/VSC hybrid DC grids, the reliability modeling and analysis of these DC grids are also presented. First, the detailed reliability model of the modular multi-level converters (MMCs) with series connected high-voltage and low-voltage bridges are developed. The active mode redundancy design is considered for the reliability model. To this end, a comprehensive whole system reliability model of the studied systems is developed. The reliability model of each subsystem is modeled in detail. Various reliability indices are calculated using this whole system reliability model. The impacts of the redundancy design of the MMCs on these indices are presented. The studies of this paper provide useful guidance for DC grid design and reliability analysis

    Control strategies of full-voltage to half-voltage operation for LCC and hybrid LCC/MMC based UHVDC systems

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    With the increasing demand of transmitting bulk-power over long-distance, the ultra high-voltage direct-current (UHVDC) transmission systems become an attractive option. Nowadays, not only the line commutated converter (LCC) based systems, but also the modular multilevel converter (MMC) based systems have reached UHVDC levels. The converter stations of UHVDC systems normally utilize two series-connected valve-groups to reduce the difficulties of device manufacturing and transportation. This high-voltage and low-voltage valve-group configuration allows the UHVDC systems to achieve a full-voltage to half-voltage operation which increases the flexibility of the systems. However, the existing research only focuses on the full-voltage to half-voltage control of LCC-UHVDC systems. The control strategies for hybrid LCC/MMC UHVDC systems are underresearched. Moreover, the approaches to reduce the load-shedding caused by the full-voltage to half-voltage control for both LCC and hybrid LCC/MMC based UHVDC systems have not been investigated. In this paper, full-voltage to half-voltage control strategies for both LCC and hybrid LCC/MMC based UHVDC systems have been proposed. Moreover, to avoid load-shedding caused by the half-voltage operation, a power rescheduling method that re-sets the power references of the half-voltage operating and full-voltage operating poles has been proposed. The proposed full-voltage to half-voltage control strategies and power rescheduling method can achieve a stable and fast control process with a minimum power loss. The proposed methods have been verified through the time-domain simulations conducted in PSCAD/EMTDC

    6-Methyl­pyridine-2(1H)-thione

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    There are two unique mol­ecules in the asymmetric unit of the title pyridine­thione derivative, C6H7NS, each of which adopts the thione rather than the mercaptan form. The rings in both mol­ecules are essentially planar, with maximum deviations from the least-squares planes through all non-H atoms of 0.021 (2) and 0.017 (2) Å. In the crystal structure, the mol­ecules form centrosymmetric cyclic dimers through inter­molecular N—H⋯S hydrogen bonds. Additional C—H(meth­yl)⋯S inter­actions generate a three-dimensional network

    Highly efficient and stable planar heterojunction solar cell based on sputtered and post-selenized Sb2Se3 thin film

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    Antimony selenide (Sb2Se3) is regarded as one of the key alternative absorber materials for conventional thin film solar cells due to its excellent optical and electrical properties. Here, we proposed a Sb2Se3 thin film solar cell fabricated using a two-step process magnetron sputtering followed by a post-selenization treatment, which enabled us to optimize the best quality of both the Sb2Se3 thin film and the Sb2Se3/CdS heterojunction interface. By tuning the selenization parameters, a Sb2Se3 thin film solar cell with high efficiency of 6.06% was achieved, the highest reported power conversion efficiency of sputtered Sb2Se3 planar heterojunction solar cells. Moreover, our device presented an outstanding open circuit voltage (VOC) of 494 mV which is superior to those reported Sb2Se3 solar cells. State and density of defects showed that proper selenization temperature could effectively passivate deep defects for the films and thus improve the device performance

    The Radiative Decay of Vector Mesons

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    In this paper, radiative decays ρ0π+πγ,π0π0γ\rho^0 \to \pi^+\pi^-\gamma, \pi^0\pi^0\gamma ,ϕK+Kγ,K0K0ˉγ\phi \to K^+K^-\gamma, K^0 \bar{K^0}\gamma are studied systematically in the U(3)_L\timesU(3)_R chiral theory of mesons. The theoretical differential spectrum with respect to photon energy and branch ratio for ρ0π+πγ\rho^0 \to \pi^+\pi^-\gamma agree well with the experimental data. Differential spectrums and branch ratios for ρ0π0π0γ,ϕK+Kγ,ϕK0K0ˉγ\rho^0 \to \pi^0\pi^0\gamma, \phi \to K^+ K^-\gamma,\phi \to K^0\bar{K^0}\gamma are predicted. The process ϕK0K0ˉγ\phi \to K^0 \bar{K^0} \gamma is relevant to precision measurment of CP-violation parameters in the kaon systerm at a ϕ\phi-factory. We give a complete estimate of the branch ratio for this decay process by including scalar resonance f0,a0f_0, a_0 poles, nonresonant smooth amplitude and an abnormal parity process with KK^* pole which hasn't been considered before. We conclude that processes with intermediate KK^* do not pose a potential background problem for ϕK0Kˉ0\phi\to K^0\bar{K}^0 CP violation experiments.Comment: Revtex file, 12 pages, 9 eps figure

    Moyal Representation of the String Field Star Product in the Presence of a B-background

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    In this paper we show that in the presence of an anti-symmetric tensor BB-background, Witten's star algebra for open string fields persists to possess the structure of a direct product of commuting Moyal pairs. The interplay between the noncommutativity due to three-string overlap and that due to the BB-background is our main concern. In each pair of noncommutative directions parallel to the BB-background, the Moyal pairs mix string modes in the two directions and are labeled, in addition to a continuous parameter, by {\it two} discrete values as well. However, the Moyal parameters are BB-dependent only for discrete pairs. We have also demonstrated the large-BB contraction of the star algebra, with one of the discrete Moyal pairs dropping out while the other giving rise to the center-of-mass noncommutative function algebra.Comment: minor notation chang

    Analysis of shared ceRNA networks and related-hub genes in rats with primary and secondary photoreceptor degeneration

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    IntroductionPhotoreceptor degenerative diseases are characterized by the progressive death of photoreceptor cells, resulting in irreversible visual impairment. However, the role of competing endogenous RNA (ceRNA) in photoreceptor degeneration is unclear. We aimed to explore the shared ceRNA regulation network and potential molecular mechanisms between primary and secondary photoreceptor degenerations.MethodsWe established animal models for both types of photoreceptor degenerations and conducted retina RNA sequencing to identify shared differentially expressed long non-coding RNAs (lncRNAs), microRNAs (miRNAs), and messenger RNAs (mRNAs). Using ceRNA regulatory principles, we constructed a shared ceRNA network and performed function enrichment and protein–protein interaction (PPI) analyses to identify hub genes and key pathways. Immune cell infiltration and drug–gene interaction analyses were conducted, and hub gene expression was validated by quantitative real-time polymerase chain reaction (qRT-PCR).ResultsWe identified 37 shared differentially expressed lncRNAs, 34 miRNAs, and 247 mRNAs and constructed a ceRNA network consisting of 3 lncRNAs, 5 miRNAs, and 109 mRNAs. Furthermore, we examined 109 common differentially expressed genes (DEGs) through functional annotation, PPI analysis, and regulatory network analysis. We discovered that these diseases shared the complement and coagulation cascades pathway. Eight hub genes were identified and enriched in the immune system process. Immune infiltration analysis revealed increased T cells and decreased B cells in both photoreceptor degenerations. The expression of hub genes was closely associated with the quantities of immune cell types. Additionally, we identified 7 immune therapeutical drugs that target the hub genes.DiscussionOur findings provide new insights and directions for understanding the common mechanisms underlying the development of photoreceptor degeneration. The hub genes and related ceRNA networks we identified may offer new perspectives for elucidating the mechanisms and hold promise for the development of innovative treatment strategies

    Xenon and Sevoflurane Provide Analgesia during Labor and Fetal Brain Protection in a Perinatal Rat Model of Hypoxia-Ischemia

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    It is not possible to identify all pregnancies at risk of neonatal hypoxic-ischemic encephalopathy (HIE). Many women use some form of analgesia during childbirth and some anesthetic agents have been shown to be neuroprotective when used as analgesics at subanesthetic concentrations. In this study we sought to understand the effects of two anesthetic agents with presumptive analgesic activity and known preconditioning-neuroprotective properties (sevoflurane or xenon), in reducing hypoxia-induced brain damage in a model of intrauterine perinatal asphyxia. The analgesic and neuroprotective effects at subanesthetic levels of sevoflurane (0.35%) or xenon (35%) were tested in a rat model of intrauterine perinatal asphyxia. Analgesic effects were measured by assessing maternal behavior and spinal cord dorsal horn neuronal activation using c-Fos. In separate experiments, intrauterine fetal asphyxia was induced four hours after gas exposure; on post-insult day 3 apoptotic cell death was measured by caspase-3 immunostaining in hippocampal neurons and correlated with the number of viable neurons on postnatal day (PND) 7. A separate cohort of pups was nurtured by a surrogate mother for 50 days when cognitive testing with Morris water maze was performed. Both anesthetic agents provided analgesia as reflected by a reduction in the number of stretching movements and decreased c-Fos expression in the dorsal horn of the spinal cord. Both agents also reduced the number of caspase-3 positive (apoptotic) neurons and increased cell viability in the hippocampus at PND7. These acute histological changes were mirrored by improved cognitive function measured remotely after birth on PND 50 compared to control group. Subanesthetic doses of sevoflurane or xenon provided both analgesia and neuroprotection in this model of intrauterine perinatal asphyxia. These data suggest that anesthetic agents with neuroprotective properties may be effective in preventing HIE and should be tested in clinical trials in the future

    The Retrohoming of Linear Group II Intron RNAs in Drosophila melanogaster Occurs by Both DNA Ligase 4–Dependent and –Independent Mechanisms

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    Mobile group II introns are bacterial retrotransposons that are thought to have invaded early eukaryotes and evolved into introns and retroelements in higher organisms. In bacteria, group II introns typically retrohome via full reverse splicing of an excised intron lariat RNA into a DNA site, where it is reverse transcribed by the intron-encoded protein. Recently, we showed that linear group II intron RNAs, which can result from hydrolytic splicing or debranching of lariat RNAs, can retrohome in eukaryotes by performing only the first step of reverse splicing, ligating their 3′ end to the downstream DNA exon. Reverse transcription then yields an intron cDNA, whose free end is linked to the upstream DNA exon by an error-prone process that yields junctions similar to those formed by non-homologous end joining (NHEJ). Here, by using Drosophila melanogaster NHEJ mutants, we show that linear intron RNA retrohoming occurs by major Lig4-dependent and minor Lig4-independent mechanisms, which appear to be related to classical and alternate NHEJ, respectively. The DNA repair polymerase θ plays a crucial role in both pathways. Surprisingly, however, mutations in Ku70, which functions in capping chromosome ends during NHEJ, have only moderate, possibly indirect effects, suggesting that both Lig4 and the alternate end-joining ligase act in some retrohoming events independently of Ku. Another potential Lig4-independent mechanism, reverse transcriptase template switching from the intron RNA to the upstream exon DNA, occurs in vitro, but gives junctions differing from the majority in vivo. Our results show that group II introns can utilize cellular NHEJ enzymes for retromobility in higher organisms, possibly exploiting mechanisms that contribute to retrotransposition and mitigate DNA damage by resident retrotransposons. Additionally, our results reveal novel activities of group II intron reverse transcriptases, with implications for retrohoming mechanisms and potential biotechnological applications
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