781 research outputs found
Free vibration of orthotropic thin plate with clamped edges
The explicit solutions for the natural frequencies and mode shapes of the orthotropic rectangular plate with four clamped edges are presented by the double finite cosine integral transform method. In the analysis procedure, the classical orthotropic rectangular thin plate is considered. Because only are the basic dynamic elasticity equations of the orthotropic thin plate adopted, it is not need prior to select the deformation function arbitrarily. Therefore, the solution developed by this paper is reasonable and theoretical. Finally, an illustrative example is given and the results are compared with those reported earlier. This method is found to be easier and effective. The results show reasonable agreement with other available results, but with a simpler and practical approach
Free vibration of orthotropic thin plate with clamped edges
The explicit solutions for the natural frequencies and mode shapes of the orthotropic rectangular plate with four clamped edges are presented by the double finite cosine integral transform method. In the analysis procedure, the classical orthotropic rectangular thin plate is considered. Because only are the basic dynamic elasticity equations of the orthotropic thin plate adopted, it is not need prior to select the deformation function arbitrarily. Therefore, the solution developed by this paper is reasonable and theoretical. Finally, an illustrative example is given and the results are compared with those reported earlier. This method is found to be easier and effective. The results show reasonable agreement with other available results, but with a simpler and practical approach
Novel Method for Measuring Structure and Semantic Similarity of XML Documents Based on Extended Adjacency Matrix
AbstractSimilarity measurement of XML documents is crucial to meet various needs of approximate searches and document classifications in XML-oriented applications. Some methods have been proposed for this purpose. Nevertheless, few methods can be elegantly exploited to depict structure and semantic information and hence to effectively measure the similarity of XML documents. In this paper, we present a new method of computing the structure and semantic similarity of XML documents based on extended adjacency matrix(EAM). Different from a general adjacency matrix, in an EAM, the structure information of not only the adjacent layers but also the ancestor-descendant layers can be stored. For measuring the similarity of two XML documents, the proposed method firstly stores the structure and semantic information in two extended adjacency matrices(M1, M2). Then it computes similarity of the two documents through cos(M1, M2) Experimental results on bench-mark data show that the method holds high efficiency and accuracy
Fractional quantum anomalous Hall phase for Raman superarray of Rydberg atoms
Rydberg atom arrays offer promising platforms for quantum simulation of
correlated quantum matter and raise great interests. This work proposes a novel
stripe-lattice model with Raman superarray of Rydberg atoms to realize bosonic
fractional quantum anomalous Hall (FQAH) phase. Two types of Rydberg states,
arranged in a supperarray configuration and with Raman-assisted dipole-exchange
couplings, are implemented to realize a minimal QAH model for hard-core bosons
populated into a topological flat band with large bulk gap under proper tunable
experimental condition. With this the bosonic FQAH phase can be further
achieved and probed feasibly. In particular, a novel quench protocol is
proposed to probe the fractionalized excitations by measuring the correlated
quench dynamics featured by fractional charge tunneling between bulk and chiral
edge modes in the open boundary.Comment: 6+5 pages, 4+1 figures, final version accepted by Adv Quantum Techno
Network pharmacology-based elucidation of the molecular mechanism underlying the anti-migraine effect of Asari Radix et Rhizoma
Purpose: To determine the molecular mechanism involved in the anti-migraine effect of Asari Radix et Rhizoma (ARR) using network pharmacology.
Methods: The compounds present in ARR were identified through information retrieval from literature and public databases, and were screened based on absorption, distribution, metabolism, excretion and toxicity. Target genes related to the selected compounds and migraine were identified or predicted from public databases. Hub genes in ARR against migraine were identified through analysis of interactions in overlapping genes between compounds and migraine target genes, based on STRING database. Gene enrichment analysis of overlapping genes was performed using Database for Annotation, Visualization and Integrated Discovery.
Results: A total of 138 compounds were selected as potential bioactive compounds in ARR. Target genes related to the selected compounds (611 genes) and migraine (278 genes) were obtained, including 71 overlapping genes. The hub genes in the anti-migraine effect of ARR were BDNF, IL6, COMT, APP and TNF. Gene enrichment analysis showed the top 10 biological processes or pathways involved in the mechanism of anti-migraine action of ARR. The tissue source of the overlapping genes was not limited to the brain. The results from gene enrichment analysis revealed that the effect of ARR on migraine was holistic, which is characteristic of traditional Chinese medicines.
Conclusion: Network pharmacology has been used to decipher the molecular mechanism involved in the action of ARR against migraine. The results provide a scientific basis for the clinical effect of ARR on migraine
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