Media 1: Silicon-on-insulator multimode-interference waveguide-based arrayed optical tweezers (SMART) for two-dimensional microparticle trapping and manipulation

Originally published in Optics Express on 28 January 2013 (oe-21-2-1520

The structure of three kind of herbal medicine.

<p>a. Rh2, b. EGCG, c.TMP.</p

Cell cycle analysis of T24/DDP cells treated with TMP using flow cytometry.

<p>Cells were cultured with different concentrations of TMP (a. 0 mM, b.2 mM, c.4 mM) for 48 h. G1, S and G2 indicated cell cycle phases.</p

Cell cycle analysis of Pumc-91/ADM cells treated with TMP using flow cytometry.

<p>Cells were cultured with different concentrations of TMP (a. 0 mM, b.2 mM, c.4 mM) for 48 h. G1, S and G2 indicated cell cycle phases.</p

Identified peptides sequences of two elevated peaks.

<p>Identified peptides sequences of two elevated peaks.</p

The expression of MRP1, GST, BCL-2, LRP and TOPO-II at the protein levels examined by western blot in Pumc-91/ADM and T24/DDP cells.

<p>a. electrophoregram. 1——Pumc-91/ADM TMP0, 2——Pumc-91/ADM TMP4, 3——T24/DDP TMP0, 4——T24/DDP TMP4. b, c. bar graph. *p<0.01 compared with the control group.</p

Effect of EGCG, Rh2 and TMP on ADM cytotoxicity in Pumc-91/ADM cells.

<p>Effect of EGCG, Rh2 and TMP on ADM cytotoxicity in Pumc-91/ADM cells.</p

Effect of TMP on DDP cytotoxicity in T24/DDP cells.

<p>Effect of TMP on DDP cytotoxicity in T24/DDP cells.</p

The changes trend between the differently expressed peaks and glycemic control.

<p>(A) Association between m/z 2756.1, m/z 3223.2 and fasting plasma glucose. (B) Association between m/z 2756.1, m/z 3223.2 and glycosylated haemoglobin A1c.</p

Analysis and comparison of urinary peptide peaks based on fasting plasma glucose of type 2 diabetes mellitus.

<p>(A) The distribution of the average peak area from the three groups and arrows indicating peaks that had statistically significant difference among three groups (p<0.05). (B) The peak area distributions of m/z 2756.1and m/z 3223.2 in all samples. Throughout comparison between two groups of the three, m/z 2756.1 and m/z 3223.2 had no significant difference (p>0.05) between GM1 and GM2.</p