4 research outputs found
Patient screening and enrolment.
<p>*One patient did not give consent. One patient was not competent to give consent, and a suitable proxy to provide consent could not be identified within inclusion time limits. **Two patients who died within 48 h of admission were excluded from the primary outcome analysis, as specified in the protocol.</p
Survival plot with futility boundary for TKM-130803 recipients.
<p>The red line denotes the futility boundary. The points and dashed line denote the number of survivors at day 14 plotted against the number of day 14 reports.</p
Baseline demographic and clinical characteristics of trial population.
<p>Baseline demographic and clinical characteristics of trial population.</p
Ebola virus RT-PCR cycle threshold values and RNA copies/ml over time.
<p>Top row: TKM-130803 recipients. Bottom row: Observational patients. RT-PCR Ct upper limit of quantitation (LOQ) = 40. RT-qPCR lower limit of quantitation = 1,000 genome copies. The Ebola virus RT-qPCR quantification is expressed as the number of genome copies/millilitre of plasma. Black diamonds denote results for survivors. Grey circles denote results for non-survivors.</p