Temporal dynamics of Chaoborus larvae (Diptera : Chaoboridae) in the tropical ecosystem (lake Ayamé I ; Côte d’Ivoire).

Chaoborus larvae are voracious predators of zooplankton able to change their specific composition and size structure. Thus they appear as competitors of fish. They also represent food for planktophage fish. The temporal dynamics of Chaoborus larvae was studied (from january to october 1997) in the fishery of Bakro (5°33’N and 3°15’W) situated in lake Ayamé I (Côte d’Ivoire). Two peaks of density were observed : the most pronouced in March (end of the major dry season) with 747 ind./m2, and another, less pronouced in June (end of the major rainy season), with 280 ind./m2. Differences between densities may well be explained by the advent of the rainy season which leads to a decline in trophic resources (zooplankton) and exposes Chaoborus larvae to predation by fish.Key-words : Chaoborus larvae, Dynamics, lake Ayamé I, Côte d’Ivoire,West Africa

Copy Number Variation in CNP267 Region May Be Associated with Hip Bone Size

Osteoporotic hip fracture (HF) is a serious global public health problem associated with high morbidity and mortality. Hip bone size (BS) has been identified as one of key measurable risk factors for HF, independent of bone mineral density (BMD). Hip BS is highly genetically determined, but genetic factors underlying BS variation are still poorly defined. Here, we performed an initial genome-wide copy number variation (CNV) association analysis for hip BS in 1,627 Chinese Han subjects using Affymetrix GeneChip Human Mapping SNP 6.0 Array and a follow-up replicate study in 2,286 unrelated US Caucasians sample. We found that a copy number polymorphism (CNP267) located at chromosome 2q12.2 was significantly associated with hip BS in both initial Chinese and replicate Caucasian samples with p values of 4.73E-03 and 5.66E-03, respectively. An important candidate gene, four and a half LIM domains 2 (FHL2), was detected at the downstream of CNP267, which plays important roles in bone metabolism by binding to several bone formation regulator, such as insulin-like growth factor-binding protein 5 (IGFBP-5) and androgen receptor (AR). Our findings suggest that CNP267 region may be associated with hip BS which might influence the FHL2 gene downstream