Multivariable Scaling for the Anomalous Hall Effect

We derive a general scaling relation for the anomalous Hall effect in ferromagnetic metals involving multiple competing scattering mechanisms, described by a quadratic hypersurface in the space spanned by the partial resistivities. We also present experimental findings, which show strong deviation from previously found scaling forms when different scattering mechanism compete in strength but can be nicely explained by our theory

Evidence of the side jump mechanism in the anomalous Hall effect in paramagnets

Persistent confusion has existed between the intrinsic (Berry curvature) and the side jump mechanisms of anomalous Hall effect (AHE) in ferromagnets. We provide unambiguous identification of the side jump mechanism, in addition to the skew scattering contribution in epitaxial paramagnetic Ni$_{34}$Cu$_{66}$ thin films, in which the intrinsic contribution is by definition excluded. Furthermore, the temperature dependence of the AHE further reveals that the side jump mechanism is dominated by the elastic scattering

A magnetic γ-Fe\u3csub\u3e2\u3c/sub\u3eO\u3csub\u3e3\u3c/sub\u3e@PANI@TiO\u3csub\u3e2\u3c/sub\u3e core–shell nanocomposite for arsenic removal \u3ci\u3evia\u3c/i\u3e a coupled visible-light-induced photocatalytic oxidation– adsorption process†

Arsenic polluted groundwater impairs human health and poses severe threats to drinking water supplies and ecosystems. Hence, an efficient method of simultaneous oxidation of As(III) to As(V), and removal of As(V) from water has triggered increasing attention. In this study, a magnetic γ-Fe2O3 core–shell heterojunction nanocomposite was synthesized by means of hydrothermal crystallization of TiO2 on the surface of the magnetic core–shell loaded with polyaniline (γ-Fe2O3@PANI@TiO2). As an efficient photocatalyst coupled with adsorption, γ-Fe2O3@PANI@TiO2 has a high light utilization and good adsorption capacity. Notably, the nanocomposite has excellent stability at various initial pH values with good reusability. Among the co-existing ions investigated, PO43- has the greatest competitive reaction. The photocatalytic oxidation of As(III) on γ-Fe2O3@PANI@TiO2 is dominated by the synergy of several active substances, with superoxide free radicals and photogenerated holes being the major players

Efficient Transposition of the piggyBac (PB) Transposon in Mammalian Cells and Mice

SummaryTransposable elements have been routinely used for genetic manipulation in lower organisms, including generating transgenic animals and insertional mutagenesis. In contrast, the usage of transposons in mice and other vertebrate systems is still limited due to the lack of an efficient transposition system. We have tested the ability of piggyBac (PB), a DNA transposon from the cabbage looper moth Trichoplusia ni, to transpose in mammalian systems. We show that PB elements carrying multiple genes can efficiently transpose in human and mouse cell lines and also in mice. PB permits the expression of the marker genes it carried. During germline transposition, PB could excise precisely from original insertion sites and transpose into the mouse genome at diverse locations, preferably transcription units. These data provide a first and critical step toward a highly efficient transposon system for a variety of genetic manipulations including transgenesis and insertional mutagenesis in mice and other vertebrates

Hemodynamic changes after transcatheter aortic valve implantation during sequential follow-ups in patients with bicuspid aortic valve compared with tricuspid aortic valve

Background: To investigate the individual sequential hemodynamic changes after transcatheter aortic valve implantation (TAVI), especially for patients with bicuspid aortic valve (BAV), in comparison with tricuspid aortic valve (TAV). Methods: The study population comprised 85 patients with severe aortic stenosis who underwent TAVI for BAV (n = 49) or TAV (n = 36) with at least two serial echocardiographic follow-ups. Doppler echocardiography was scheduled to be performed at discharge and 1, 3, 6 months and 1 year after the procedure. D peak transvalvular velocities and D mean transvalvular gradients were calculated as the difference at follow-up time points and discharge. Paravalvular leak (PVL) was assessed as another indicator for prosthesis performance. Results: Comparisons between patients with BAV and TAV revealed similar gradient performances (1.00 [–2.00, 2.00] vs. 1.00 [–0.25, 5.00] mm Hg, p = 0.57 at 1 month; –0.71 ± 7.52 vs. 1.55 ± 3.97 mm Hg, p = 0.21 at 3 months; 0.96 ± 7.81 vs. 1.53 ± 5.85 mm Hg, p = 0.79 at 6 months; 1.00 [–0.50, 2.25] vs. 3.00 [–0.50, 7.50] mm Hg, p = 0.07 at 1 year). Moreover, the incidence of ≥ mild PVL was not significantly different in patients with BAV and TAV during follow-up (34.88% vs. 19.35%, p = 0.14 at 1 month; 45.83% vs. 27.27%, p = 0.19 at 3 months; 30.00% vs. 23.53%, p = 0.89 at 6 months; 30.00% vs. 17.65%, p = 0.56 at 1 year). Conclusions: TAVI is effective and applicable in BAV anatomy with sustained and acceptable mid- -term prosthesis hemodynamic performance. (Cardiol J 2017; 24, 4: 350–357

Comparison of the Inhibitory Potential of Bavachalcone and Corylin against UDP-Glucuronosyltransferases

Bavachalcone and corylin are two major bioactive compounds isolated from Psoralea corylifolia L., which has been widely used as traditional Chinese medicine for many years. As two antibiotic or anticancer drugs, bavachalcone and corylin are used in combination with other drugs; thus it is necessary to evaluate potential pharmacokinetic herb-drug interactions (HDI) of the two bioactive compounds. The aim of the present study was to compare the effects of liver UDP-glucuronosyltransferase (UGT) 1A1, UGT1A3, UGT1A7, UGT1A8, UGT 1A10, and UGT2B4 inhibited by bavachalcone and corylin. 4-Methylumbelliferone (4-MU) was used as a nonspecific “probe” substrate. Bavachalcone had stronger inhibition on UGT1A1 and UGT1A7 than corylin which did not inhibit UGT1A1, UGT1A3, UGT1A7, UGT1A8, UGT1A10, and UGT2B4. Data fitting using Dixon and Lineweaver-Burk plots demonstrated the noncompetitive inhibition of bavachalcone against UGT1A1 and UGT1A7-mediated 4-MU glucuronidation reaction. The values of inhibition kinetic parameters (Ki) were 5.41 μM and 4.51 μM for UGT1A1 and UGT1A7, respectively. The results of present study suggested that there was a possibility of UGT1A1 and UGT1A7 inhibition-based herb-drug interaction associated with bavachalcone and provided the basis for further in vivo studies to investigate the HDI potential between bavachalcone and UGT substrates

Developments of a 2D Position Sensitive Neutron Detector

Chinese Spallation Neutron Source (CSNS), one project of the 12th five-year-plan scheme of China, is under construction in Guangdong province. Three neutron spectrometers will be installed at the first phase of the project, where two-dimensional position sensitive thermal neutron detectors are required. Before the construction of the neutron detector, a prototype of two-dimensional 200 mmx200 mm Multi-wire Proportional Chamber (MWPC) with the flowing gas of Ar/CO2 (90/10) has been constructed and tested with the 55Fe X-Ray using part of the electronics in 2009, which showed a good performance. Following the test in 2009, the neutron detector has been constructed with the complete electronics and filled with the 6atm.3He + 2.5atm.C3H8 gas mixture in 2010. The neutron detector has been primarily tested with an Am/Be source. In this paper, some new developments of the neutron detector including the design of the high pressure chamber, the optimization of the gas purifying system and the gas filling process will be reported. The results and discussion are also presented in this paper.Comment: 5 page