Letter to the Editor

The paper by Alfons, Croux and Gelper (2013), Sparse least trimmed squares regression for analyzing high-dimensional large data sets, considered a combination of least trimmed squares (LTS) and lasso penalty for robust and sparse high-dimensional regression. In a recent paper [She and Owen (2011)], a method for outlier detection based on a sparsity penalty on the mean shift parameter was proposed (designated by "SO" in the following). This work is mentioned in Alfons et al. as being an "entirely different approach." Certainly the problem studied by Alfons et al. is novel and interesting.Comment: Published in at http://dx.doi.org/10.1214/13-AOAS640 the Annals of Applied Statistics (http://www.imstat.org/aoas/) by the Institute of Mathematical Statistics (http://www.imstat.org

Estudio gramatical aplicado a un texto turístico alemán : rutas turísticas por Alemania recomendadas por la UNESCO

Universidad de Sevilla. Grado en Turism

3-(3,4-Dimeth­oxy­phen­yl)-4-(2-meth­oxy­anilino)furan-2(5H)-one

In the title compound, C19H19NO5, the furan­one unit makes a dihedral angle of 30.93 (6)° with the benzene ring and a dihedral angle of 9.51 (6)° with the aniline ring. In the crystal, inter­molecular C—H⋯O hydrogen bonds and C—H⋯π contacts link the mol­ecules into sheets. A weak intramolecular hydrogen bond is also observed

A novel multi-party semiquantum private comparison protocol of size relationship with d-dimensional single-particle states

By using d-level single-particle states, the first multi-party semiquantum private comparison (MSQPC) protocol which can judge the size relationship of private inputs from more than two classical users within one execution of protocol is put forward. This protocol requires the help of one quantum third party (TP) and one classical TP, both of whom are allowed to misbehave on their own but cannot conspire with anyone else. Neither quantum entanglement swapping nor unitary operations are necessary for implementing this protocol. TPs are only required to perform d-dimensional single-particle measurements. The correctness analysis validates the accuracy of the compared results. The security analysis verifies that both the outside attacks and the participant attacks can be resisted.Comment: 19 pages, 2 figures, 2 table

Bioengineering Investigations of Pulmonary Vascular Function in Pulmonary Hypertension: In Vivo, In Vitro and Modeling Studies

Pulmonary hypertension (PH) is characterized by chronic high blood pressure in the pulmonary arteries (PAs) and is an important cause of morbidity and mortality in children and adults. During the development of PH, the pulmonary circulation displays significant arterial remodeling, which yields changes in mechanical behavior and subsequently, of pulmonary vascular function (PVF). Recent clinical findings suggest that knowing the change in PVF is important for accurate prognosis of PH and its severity, and may be relevant in developing treatment strategies. One clinical effort has focused on the measurement of pulmonary vascular input impedance, which can provide comprehensive characterization of PH and the mechanical properties and behavior of proximal PAs; these properties strongly affect the impedance and right ventricular afterload. In this dissertation, the measurement uncertainty in the pulmonary vascular input impedance estimated from pulsed-wave Doppler-measured velocity and pressure measurements is examined to provide the guidance for the use of impedance in clinical studies. To examine the mechanical properties of proximal PAs, in vitro studies on the arterial remodeling including mechanical and histological aspects due to chronic hypoxia in the proximal PAs of both adult rat and neonatal calf models of PH are performed to seek mechanobiological relation of the proximal PAs. Combining in vitro and in vivo arterial geometry data from main PA (MPA) of neonatal calves, the in vivo stretch distribution and collagen engagement in MPAs are examined and the impact of residual stretch and arterial remodeling is then investigated. Finally, an approach is proposed to quantify the appropriateness of constitutive models for proximal PAs by comparing the predicted and measured pressure-diameter curves in calf MPAs. With the constitutive model, the relation between the collagen contribution to the pressure loading at the physiological conditions and the PH disease state can be established, and such concept can be applied to clinical studies for the diagnosis of PH. Overall, these investigations of PVF in PH from in vivo, in vitro and modeling studies can provide a better understanding of functional changes of the entire pulmonary circulation, which in turn will be useful to the diagnosis and treatment of PH

(Z)-2-Acetamido-3-(4-chloro­phen­yl)acrylic acid

In the title compound, C11H10ClNO3, the mol­ecule consists of a benzene ring and an acetamido­acrylic acid unit on opposite sides of the C=C double bond. In the crystal, inter­molecular O—H⋯O and N—H⋯O hydrogen bonds assemble the mol­ecules into infinite two-dimensional ribbons. These ribbons are linked into a network by inter­molecular C—H⋯π contacts

(Z)-2-Hydr­oxy-3-(4-methoxy­phen­yl)acrylic acid

In the structure of the title compound, C10H10O4, inversion dimers linked by pairs of O—H⋯O hydrogen bonds link the carboxylic acid groups. Further O—H⋯O links cross-link the dimers into sheets running along the b-axis direction