741 research outputs found
Prevalence of methicillin-resistant Staphylococcus aureus among large commercial pig herds in South Africa
The prevalence of nasal carrier status of methicillin-resistant Staphylococcus aureus (MRSA) in pigs has been described elsewhere, but is unknown in South Africa. To address concerns that exist regarding the zoonotic risk that carriers pose to workers, the herd-level prevalence of MRSA was determined among 25 large (> 500 sows) commercial pig herds in South Africa, representing 45% of the large commercial herds in the country. From each herd, the nasal contents of 18 finisher pigs were sampled at the abattoir, pooled into three and selectively cultured to determine the presence of MRSA. A herd was classified as MRSA-positive if one or more of the three pooled samples cultured positive. Three of the 25 herds tested positive for MRSA, equating to a 12% herd prevalence (95% CI: 7% – 23%) among South African commercial piggeries. The prevalence of nasal MRSA carriers among large commercial pig herds in South Africa was low compared to what has been reported elsewhere and suggests a relatively low zoonotic MRSA risk to workers in South African commercial piggeries and abattoirs
Маргінеси „чужої” мови в романі Джені Ерпенбек „Словник”
Запропонована розвідка є однією із численних спроб постколоніальних феміністичних студій відповісти на питання, чи може підпорядковане промовляти. Йдеться про сучасну німецьку жіночу прозу Дженні Ерпенбек, зокрема її роман „Словник”, та визначення статусу жінки з комплексом дотичних до нього проблем у ході вписування жіночого, почасти автобіографічного досвіду, в національну історію тоталітарного минулого на прикладі запропонованого роману. Так, автобіографічні рефлексії письменниці щодо нацистського та соціалістичного режимів насилля презентують жінку як суб’єкта, що говорить, залишаючись поза структурою мови. Процес пригадування задля пошуків істини розкриває механізми поглинання мови ідеологічним міфом. Відтак духовний простір жінки залишається на маргінесах мови, суспільства, історії.The present study is based on the women’s autobiographic experience to tell the self- and national history of the totalitarian regime. The study seeks some the most important postcolonial aspects of the female existence in the mirror of the ideological language. To recognize the problem of language and violence is to show the mechanism of the women’s removing to the linguistic margins. In agree with the main postcolonial tendencies the article concludes such actual theories to prove these aspects: the term of the contemporal myth by R. Barthes, the discourse of language and violence in the feministic theory of L. Terel, the conception of the female language in the work of E. Showalter, the multicultural points of view of G.Ch. Spivak, the Strenger’s identity of B. Valdenfels
Seroprevalence and factors associated with Coxiella burnetii exposure in goats in Moretele
Infection with Coxiella burnetii causes significant economic impact and poses zoonotic risk to
people exposed to livestock, yet few studies in South Africa have assessed seroprevalence of
C. burnetii infection and no information is available for goats. Very little information is available
regarding risk factors and outcomes of C. burnetii infection in peri-urban farming areas where
widespread mixing of ruminants occurs. This study estimated the seroprevalence of C. burnetii
infection among communally farmed goats in an area adjacent to the densely populated
Gauteng province. Sera were collected from 216 goats in 39 herds, and questionnaires were
completed to establish management practices as potential risk factors. C. burnetii antibody
testing was done by ELISA. Thirty two out of 216 goats tested positive for C. burnetii antibodies
and the overall seroprevalence, adjusted for sampling weights and clustering, was 18.4% (95%
confidence interval [CI]: 12.2% – 23.5%). The intraclass correlation coefficient was 0.06,
indicating low-to-moderate clustering. Multiple logistic regression showed age was
significantly associated with seropositivity, with higher seroprevalence in animals ≥ 19 months
old (26%) than animals ≤ 6 months old (6%) (odds ratio [OR]: 6.6; p = 0.010). We concluded
C. burnetii infection is common in goats in Moretele and a potential cause of abortion in goats
and poses the potential zoonotic disease risk.http://www.ojvr.orgProduction Animal Studie
Parallel multicentre randomised trial of a clinical trial question prompt list in patients considering participation in phase 3 cancer treatment trials
Accepted 9 February 2017Objective: To evaluate the effect of a clinical trial question prompt list in patients considering enrolment in cancer treatment trials. Setting: Tertiary cancer referral hospitals in three state capital cities in Australia. Participants: 88 patients with cancer attending three cancer centres in Australia, who were considering enrolment in phase 3 treatment trials, were invited to enrol in an unblinded randomised trial of provision of a clinical trial question prompt list (QPL) before consenting to enrol in the treatment trial. Interventions: We developed and pilot tested a targeted QPL for patients with cancer considering clinical trial participation (the clinical trial QPL). Consenting patients were randomised to receive the clinical trial QPL or not before further discussion with their oncologist and/or trial nurse about the treatment trial. Primary and secondary outcomes: Questionnaires were completed at baseline and within 3â €..weeks of deciding on treatment trial participation. Main outcome measure: scores on the Quality of Informed Consent questionnaire (QuIC). Results: 88 patients of 130 sought for the study were enrolled (43 males), and 45 received the clinical trial QPL. 49% of trials were chemotherapy interventions for patients with advanced disease, 35% and 16% were surgical adjuvant and radiation adjuvant trials respectively. 70 patients completed all relevant questionnaires. 28 of 43 patients in the control arm compared with 39 of 45 patients receiving the clinical trial QPL completed the QuIC (p=0.0124). There were no significant differences in the QuIC scores between the randomised groups (QuIC part A p=0.08 and QuIC part B p=0.92). There were no differences in patient satisfaction with decisions or in anxiety levels between the randomised groups. Conclusions: Use of a question prompt list did not significantly change the QuIC scores in this randomised trial. ANZCTR 12606000214538 prospectively registered 31/5/2006. Trial registration number: Results, ACTRN12606000214538.Martin H N Tattersall, Michael Jefford, Andrew Martin, Ian Olver, John F Thompson, Richard F Brown, Phyllis N Buto
Temporal and spatial history of Rift Valley fever in South Africa : 1950 to 2011
Several outbreaks of Rift Valley fever (RVF) have been documented in South Africa since it first
occurred in the country in 1950. However, there is no comprehensive account of the timing,
location and extent of all known outbreaks. As part of a study investigating the epidemiology
of RVF in South Africa, a full history of outbreaks was compiled using references to the disease
in South Africa from scientific literature, annual reports, disease reports and animal disease
databases. The geographic location and temporal occurrence of each outbreak were recorded
as accurately as allowed by the available records. The result was a better and more complete
picture than has hitherto been available of the spatial and temporal distribution of RVF in
South Africa for the period between 1950 and 2011. Several smaller outbreaks which had not
been described previously in literature were documented. Extensive outbreaks occurred in
the central interior of the country (Free State, Eastern Cape and Northern Cape provinces),
interspersed with smaller outbreaks or long intervening periods of absence, whilst smaller
outbreaks occurred in the eastern part of the country (KwaZulu-Natal, Mpumalanga and
Gauteng).Scan this QR
code with your
smart phone or
mobile device
to read online.N.J.P. (University of Pretoria) performed the study and wrote
the article. P.N.T. (University of Pretoria) was the academic
study leader for the MSc degree of which this report formed
part and assisted in study design, data analysis and writing
of the article.http://www.ojvr.orgam2013ab2013ab201
Approaches to increase recovery of bacterial and fungal abortion agents in domestic ruminants
DATA AVAILABILITY : All relevant data are within the paper.Abortions in domestic ruminants cause significant economic losses to farmers. Determining
the cause of an abortion is important for control efforts, but it can be challenging. All available
diagnostic methods in the bacteriology laboratory should be employed in every case due to
the many limiting factors (autolysis, lack of history, range of samples) that complicate the
investigation process. The purpose of this study was to determine whether the recovery of
diagnostically significant isolates from domestic ruminant abortion cases could be increased
through the use of a combination of the existing aerobic culture and Brucella selective method
with methods that are commonly recommended in the literature reporting abortion
investigations. These methods are examination of wet preparations and impression smears
stained by the modified Ziehl–Neelsen method, anaerobic, microaerophilic, Leptospira,
Mycoplasma and fungal culture. Samples of placenta and aborted foetuses from 135 routine
clinical abortion cases of cattle (n = 88), sheep (n = 25) and goats (n = 22) were analysed by the
new combination of methods. In 46 cases, bacteria were identified as aetiological agents and
in one case a fungus. Isolation of Brucella species increased to 7.4% over two years compared
with the previous 10 years (7.3%), as well as Campylobacter jejuni (n = 2) and Rhizopus species
(n = 1). Salmonella species (5.9%) and Trueperella pyogenes (4.4%) were also isolated more often.
In conclusion, the approach was effective in removing test selection bias in the bacteriology
laboratory. The importance of performing an in-depth study on the products of abortion by
means of an extensive, combination of conventional culture methods was emphasised by
increased isolation of Brucella abortus and isolation of C. jejuni. The combination of methods
that yielded the most clinically relevant isolates was aerobic, microaerophilic, Brucella and
fungal cultures.AGRISeta and Red Meat Research and Development South Africa.http://www.ojvr.org/index.php/ojvram2024Production Animal StudiesVeterinary Tropical DiseasesSDG-03:Good heatlh and well-bein
The effect of unrestricted milk feeding on the growth and health of Jersey calves
This study was conducted to determine the effect of feeding high milk volumes on the
growth rate, health and cross-sucking behaviour in group-fed Jersey calves. Three-day-old
heifers (n = 120) in a seasonal calving dairy herd were randomly assigned to one of 6
treatment groups. Three groups received high milk volumes (HMV), consisting of ad libitum
milk or milk replacer feeding twice a day, while 3 groups received restricted milk volumes
(RMV), consisting of 2 twice daily, during the pre-weaning period. After a pre-weaning
period during which feeding was reduced to once daily, all calves were weaned at 42 days
and monitored until 60 days of age.Adjusting for birth mass, birth date,damparity and sire,
average daily mass gain (ADG), both pre-weaning (days 0–42) and overall (days 0–60), was
higher inHMVthan inRMVcalves (P<0.001).After weaning, growth rates showed no differences
and at 60 days of age the HMV calves maintained a 6.74 kg advantage in mean
body mass (P < 0.001). The mean intake of dry starter feed was higher in RMV than in
HMVcalves. Overall feed conversion rate ofHMVcalves was 9.6%better thanRMVcalves.
However, the variable cost per kg mass gain was 12 % higher for HMV calves. In the
RMV groups 75 % of calves showed cross-sucking behaviour pre-weaning and 18 %
post-weaning, whereas in HMV calves the proportions were 2 % and 7 %, respectively.
There was no significant effect of milk volume on the incidence of diarrhoea.We conclude
that the feeding of high volumes of milk to Jersey calves has a positive effect on growth rate,
without compromising health or reducing solid feed intake after weaning. However, the
higher cost of such a feeding system may limit its implementation.http://www.journals.co.za/ej/ejour_savet.htm
The effect of preconditioning on production and antibiotic use in a South African beef feedlot
CONTEXT : There is pressure on production veterinarians to reduce the use of antibiotics in intensive beef production systems.
AIMS : The present study investigated whether preconditioning – the process whereby weaned calves destined for the feedlot are prepared over a period of time – reduced antibiotic treatment events, and improved health and production of calves in a South African feedlot.
METHODS : Preconditioned calves (n = 301) and control calves (n = 332) were sourced from the same origin on two occasions, and arrived at the feedlot on the same day. Bovine respiratory disease (BRD) was defined as the ‘pulling’ of clinically sick calves from feedlot pens, followed by the standard protocol for treatment of BRD (including antibiotic treatment). Outcome variables related to health were BRD overall incidence (pulling), BRD re-pulling and lung lesion scores. Production outcome variables measured were carcass weight, carcass average daily gain (ADG) and days on feed (DOF). Initial carcass weight was estimated from shrunk liveweight in order to estimate the effect of preconditioning on carcass gain, the most economically relevant outcome. Statistical analyses were done using multiple linear, logistic and Cox regression. Predictor variables were preconditioning vs control, gender, starting weight, DOF, pulling for BRD and carcass ADG.
KEY RESULTS : A lower proportion of preconditioned calves were pulled and a lower proportion of pulled calves were re-pulled for BRD compared with control calves (8 vs 17% and 8 vs 16%, respectively, P < 0.01). A higher proportion of preconditioned calves compared with control calves were market ready at 90 DOF (89 vs 67%, P < 0.01). In the multivariable models preconditioning was associated with a 200 g/d increase in carcass growth rate (P < 0.01) and with a 17.7 kg increase in overall carcass gain (P < 0.01) after adjusting for gender and DOF.
CONCLUSIONS : Preconditioning reduced the incidence and severity of BRD and feedlot standing time and improved production of calves in South African feedlots.
IMPLICATIONS : Preconditioning has the potential to add value to the beef feedlot by reducing the formation of antimicrobial resistance while improving the profitability of the feedlot.Red Meat Research and Development South Africa (RMRD-SA)http://www.publish.csiro.au/anhj2021Production Animal Studie
Patterns of rabies cases in South Africa between 1993 and 2019, including the role of wildlife
DATA AVAILABILITY STATEMENT : The data that support the findings of this study are openly available in DALRRD. (2019). Rabies Data South Africa from http://www.daff.gov.za/daffweb3/Branches/Agricultural-Production-Health-Food-Safety/Animal-Health/Epidemiology/diseasedatabase], reference number [17].Rabies is a global viral zoonosis endemic to South Africa, resulting in fatal encephalitis in warm-blooded animals, including humans. The loss of human lives and economic losses in rural areas through loss of livestock are substantial. A review was conducted of all confirmed animal rabies cases in South Africa from 1993 to 2019, with a total of 11 701 cases identified to species level to assess the role that wildlife plays in the epidemiology of rabies. A spatio-temporal cluster analysis using a discrete Poisson space-time probability model, accounting for underlying estimated dog and livestock densities, identified 13 significant clusters (p < .05). These included four long-term clusters lasting more than 8 years in duration and seven short-term clusters lasting less than 2 years, with the remaining two clusters being of intermediate length. Outside of these endemic clusters, wildlife outbreaks in the remainder of South Africa were often less than one and a half years in duration most likely due to the rapid decline of wildlife vectors, especially jackals associated with rabies infection. Domestic dogs accounted for 59.8% of cases, with domestic cats (3.2%), livestock (21.1%) and wildlife (15.8%) making up the remainder of the cases. Yellow mongoose (Cynictis penicillata) was the most frequently affected wildlife species, followed by bat-eared fox (Otocyon megalotis), black-backed jackal (Canis mesomelas), meerkat (Suricata suricatta) and aardwolf (Proteles cristatus). Rabies in wildlife species followed different spatial distributions: black-backed jackal cases were more common in the north-western parts of South Africa, yellow mongoose cases more frequent in central South Africa, and bat-eared fox and aardwolf cases were more frequent in southern and western South Africa. Clusters often spanned several provinces, showing the importance of coordinated rabies control campaigns across administrative boundaries, and high-risk areas were highlighted for rabies in South Africa.The South African Veterinary Association Wildlife Group.http://wileyonlinelibrary.com/journal/tbedhj2023Centre for Veterinary Wildlife StudiesProduction Animal StudiesVeterinary Tropical Disease
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