28,203 research outputs found

    Experimental Observations of Group Synchrony in a System of Chaotic Optoelectronic Oscillators

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    We experimentally demonstrate group synchrony in a network of four nonlinear optoelectronic oscillators with time-delayed coupling. We divide the nodes into two groups of two each, by giving each group different parameters and by enabling only inter-group coupling. When coupled in this fashion, the two groups display different dynamics, with no isochronal synchrony between them, but the nodes in a single group are isochronally synchronized, even though there is no intra-group coupling. We compare experimental behavior with theoretical and numerical results

    Groups of Fibonacci type revisited

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    This article concerns a class of groups of Fibonacci type introduced by Johnson and Mawdesley that includes Conway?s Fibonacci groups, the Sieradski groups, and the Gilbert-Howie groups. This class of groups provides an interesting focus for developing the theory of cyclically presented groups and, following questions by Bardakov and Vesnin and by Cavicchioli, Hegenbarth, and Repov?s, they have enjoyed renewed interest in recent years. We survey results concerning their algebraic properties, such as isomorphisms within the class, the classification of the finite groups, small cancellation properties, abelianizations, asphericity, connections with Labelled Oriented Graph groups, and the semigroups of Fibonacci type. Further, we present a new method of proving the classification of the finite groups that deals with all but three groups

    The aspherical Cavicchioli-Hegenbarth-Repovš generalized Fibonacci groups

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    The Cavicchioli–Hegenbarth–Repovš generalized Fibonacci groups are defined by the presentations Gn (m, k) = 〈x 1, … , xn | xixi+m = xi+k (1 ⩽ i ⩽ n)〉. These cyclically presented groups generalize Conway's Fibonacci groups and the Sieradski groups. Building on a theorem of Bardakov and Vesnin we classify the aspherical presentations Gn (m, k). We determine when Gn (m, k) has infinite abelianization and provide sufficient conditions for Gn (m, k) to be perfect. We conjecture that these are also necessary conditions. Combined with our asphericity theorem, a proof of this conjecture would imply a classification of the finite Cavicchioli–Hegenbarth–Repovš groups

    High-throughput measurement of dictyostelium discoideum macropinocytosis by flow cytometry

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    Large-scale non-specific fluid uptake by macropinocytosis is important for the proliferation of certain cancer cells, antigen sampling, host cell invasion and the spread of neurodegenerative diseases. The commonly used laboratory strains of the amoeba Dictyostelium discoideum have extremely high fluid uptake rates when grown in nutrient medium, over 90% of which is due to macropinocytosis. In addition, many of the known core components of mammalian macropinocytosis are also present, making it an excellent model system for studying macropinocytosis. Here, the standard technique to measure internalized fluid using fluorescent dextran as a label is adapted to a 96-well plate format, with the samples analyzed by flow cytometry using a high-throughput sampling (HTS) attachment. Cells are fed non-quenchable fluorescent dextran for a pre-determined length of time, washed by immersion in ice-cold buffer and detached using 5 mM sodium azide, which also stops exocytosis. Cells in each well are then analyzed by flow cytometry. The method can also be adapted to measure membrane uptake and phagocytosis of fluorescent beads or bacteria. This method was designed to allow measurement of fluid uptake by Dictyostelium in a high-throughput, labor and resource efficient manner. It allows simultaneous comparison of multiple strains (e.g. knockout mutants of a gene) and conditions (e.g. cells in different media or treated with different concentrations of inhibitor) in parallel and simplifies time-courses.</p

    Are UK SMEs with active websites more likely to achieve both innovation and growth?

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    Purpose: This paper examines the impact of developing more active Websites and increasing E-commerce on the relationship between innovation and growth performance in SMEs. Using the existing literature and empirical analysis the study considers the potential of engagement with the Internet to achieve the often hard to attain ambition of both innovation and growth. Design/methodology/approach: In order to examine the relationship, data is drawn from the Federation of Small Businesses (FSB) 'Lifting the Barriers to Growth Survey'. In order to establish whether the use of more sophisticated Websites is associated with being an innovative high performance business, whilst controlling for other firm and entrepreneurial characteristics, multivariate approaches in the form of multinominal logits and discriminant function analysis are utilised. Findings: The results suggest that although theoretically Websites with tools allowing interaction with customers or suppliers could benefit SMEs through a reduction in transaction costs and wider access to information, enabling them to jointly experience innovation and growth, in practice there is less evidence that this occurs. If anything those firms with active websites are more likely to be innovative, but no more likely to be both innovative and achieving growth. Implications: These results suggest that further work must be undertaken to establish whether SMEs should be encouraged to make such investments and if so what additional help is required to ensure that investments in this digital infrastructure achieves an appropriate return on investment. Originality/Value: The results are of importance to both SMEs and policy makers providing insight into the nature of potential benefits from Website development using a large dataset. A clear need to investigate further how more innovative SMEs can benefit from company Websites and ecommerce to grow is identified
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