7,174 research outputs found
Geometry dependence of the clogging transition in tilted hoppers
We report the effect of system geometry on the clogging of granular material
flowing out of flat-bottomed hoppers with variable aperture size D. For such
systems, there exists a critical aperture size Dc at which there is a
divergence in the time for a flow to clog. To better understand the origins of
Dc, we perturb the system by tilting the hopper an angle Q and mapping out a
clogging phase diagram as a function of Q and D. The clogging transition
demarcates the boundary between the freely-flowing (large D, small Q) and
clogging (small D, large Q) regimes. We investigate how the system geometry
affects Dc by mapping out this phase diagram for hoppers with either a circular
hole or a rectangular narrow slit. Additionally, we vary the grain shape,
investigating smooth spheres (glass beads), compact angular grains (beach
sand), disk-like grains (lentils), and rod-like grains (rice). We find that the
value of Dc grows with increasing Q, diverging at pi-Qr where Qr is the angle
of repose. For circular apertures, the shape of the clogging transition is the
same for all grain types. However, this is not the case for the narrow slit
apertures, where the rate of growth of the critical hole size with tilt angle
depends on the material
Bioelectrical Impedance Analysis (BIA)-derived Phase Angle (PA) is a practical aid to nutritional assessment in hospital in-patients
Background: Nutritional status can be difficult to assess. Bioelectrical impedance analysis (BIA)-derived phase angle (PA), and the plasma markers citrulline and transthyretin (pre-albumin) have the potential to assist, but the protocol of fasting and resting for BIA renders the investigation impractical for routine use, especially so in populations at high risk of malnutrition. Aims: 1- To clarify whether starving and resting are necessary for reliable measurement of PA. 2- To identify whether PA, citrulline and transthyretin correlate with nutritional status. Methods: Eighty consenting adult in-patients were recruited. Nutritional status was determined by subjective global assessment (SGA) used as gold standard. The Malnutrition Universal Screening Tool (MUST) was used and anthropometric measurements were performed. Serum was analysed for citrulline and transthyretin. PA was measured using Bodystat 4000. The PA was considered to define malnutrition when lower than reference ranges for sex and age, and severe malnutrition if more than 2 integers below the lower limit. Anthropometric measurements were categorised according to WHO reference centiles. Ordinal logistic regression estimated the strength of association of PA, citrulline and transthyretin with SGA. PA values in the different metabolic states were compared using paired t tests. Results: All 80 subjects completed the BIA and the nutritional assessments in the 3 different states; 14 declined to provide blood samples for the biochemical assays. Malnutrition was identified in 32 cases, severe malnutrition in 14 cases, the remaining 34 cases were deemed not to be malnourished. PA was strongly inversely associated with SGA (Odds Ratio [OR] per unit increase = 0.21, CI 0.12-0.37, p < 0.001). PA was not influenced by exercise (p=0.134) or food intake (p=0.184). Transthyretin was inversely associated with malnourished/severely malnourished states (OR = 0.98, 95% CI 0.97 – 0.99, p = 0.001), but had poorer predictive values than PA. There was no significant association between citrulline concentration and SGA (OR = 1.01, 95% CI 0.99-1.04, p = 0.348). Conclusions: The BIA-derived PA reliably identifies malnutrition. It is strongly associated with SGA but requires less skill and experience, and out-performs circulating transthyretin, rendering it a promising and less operator-dependent tool for assessing nutritional status in hospital patients. Our novel demonstration that fasting and bed-rest are unnecessary consolidates that position
Study of the Hindrance Effect in Sub-barrier Fusion Reactions
We have measured the fusion cross sections of the 12C(13C, p)24Na reaction
through off-line measurement of the beta-decay of 24Na using the beta-gamma
coincidence method. Our new measurements in the energy range of Ec.m. = 2.6-3.0
MeV do not show an obvious S-factor maximum but a plateau. Comparison between
this work and various models is presented.Comment: 3 pages, 3 figures, Talk at the "10th International Conference on
Nucleus-Nucleus Collisions", Beijing, 16-21 August 200
A numerical study of the development of bulk scale-free structures upon growth of self-affine aggregates
During the last decade, self-affine geometrical properties of many growing
aggregates, originated in a wide variety of processes, have been well
characterized. However, little progress has been achieved in the search of a
unified description of the underlying dynamics. Extensive numerical evidence
has been given showing that the bulk of aggregates formed upon ballistic
aggregation and random deposition with surface relaxation processes can be
broken down into a set of infinite scale invariant structures called "trees".
These two types of aggregates have been selected because it has been
established that they belong to different universality classes: those of
Kardar-Parisi-Zhang and Edward-Wilkinson, respectively. Exponents describing
the spatial and temporal scale invariance of the trees can be related to the
classical exponents describing the self-affine nature of the growing interface.
Furthermore, those exponents allows us to distinguish either the compact or
non-compact nature of the growing trees. Therefore, the measurement of the
statistic of the process of growing trees may become a useful experimental
technique for the evaluation of the self-affine properties of some aggregates.Comment: 19 pages, 5 figures, accepted for publication in Phys.Rev.
Complete Genome Sequence and Comparative Metabolic Profiling of the Prototypical Enteroaggregative Escherichia coli Strain 042
Background \ud
Escherichia coli can experience a multifaceted life, in some cases acting as a commensal while in other cases causing intestinal and/or extraintestinal disease. Several studies suggest enteroaggregative E. coli are the predominant cause of E. coli-mediated diarrhea in the developed world and are second only to Campylobacter sp. as a cause of bacterial-mediated diarrhea. Furthermore, enteroaggregative E. coli are a predominant cause of persistent diarrhea in the developing world where infection has been associated with malnourishment and growth retardation. \ud
\ud
Methods \ud
In this study we determined the complete genomic sequence of E. coli 042, the prototypical member of the enteroaggregative E. coli, which has been shown to cause disease in volunteer studies. We performed genomic and phylogenetic comparisons with other E. coli strains revealing previously uncharacterised virulence factors including a variety of secreted proteins and a capsular polysaccharide biosynthetic locus. In addition, by using Biologâ„¢ Phenotype Microarrays we have provided a full metabolic profiling of E. coli 042 and the non-pathogenic lab strain E. coli K-12. We have highlighted the genetic basis for many of the metabolic differences between E. coli 042 and E. coli K-12. \ud
\ud
Conclusion \ud
This study provides a genetic context for the vast amount of experimental and epidemiological data published thus far and provides a template for future diagnostic and intervention strategies
Nondispersive hole transport in a spin-coated dendrimer film measured by the charge-generation-layer time-of-flight method
Published versio
Highly efficient single-layer dendrimer light-emitting diodes with balanced charge transport
Published versio
Axial Vector Coupling Constant in Chiral Colour Dielectric Model
The axial vector coupling constants of the decay processes of neutron
and hyperon are calculated in SU(3) chiral colour dielectric model (CCDM).
Using these axial coupling constants of neutron and hyperon, in CCDM we
calculate the integrals of the spin dependent structure functions for proton
and neutron. Our result is similar to the results obtained by MIT bag and
Cloudy bag models.Comment: 9 pages, Latex file, no figure, to appear in Phys. Rev.
Vortex lines in the three-dimensional XY model with random phase shifts
The stability of the ordered phase of the three-dimensional XY-model with
random phase shifts is studied by considering the roughening of a single
stretched vortex line due to the disorder. It is shown that the vortex line may
be described by a directed polymer Hamiltonian with an effective random
potential that is long range correlated. A Flory argument estimates the
roughness exponent to and the energy fluctuation exponent to
, thus fulfilling the scaling relation . The
Schwartz-Edwards method as well as a numerical integration of the corresponding
Burger's equation confirm this result. Since the ordered phase of the
original XY-model is stable.Comment: 8 pages RevTeX, 3 eps-figures include
Disorder-Induced Depinning Transition
The competition in the pinning of a directed polymer by a columnar pin and a
background of random point impurities is investigated systematically using the
renormalization group method. With the aid of the mapping to the noisy-Burgers'
equation and the use of the mode-coupling method, the directed polymer is shown
to be marginally localized to an arbitrary weak columnar pin in 1+1 dimensions.
This weak localization effect is attributed to the existence of large scale,
nearly degenerate optimal paths of the randomly pinned directed polymer. The
critical behavior of the depinning transition above 1+1 dimensions is obtained
via an -expansion.Comment: 47 pages in revtex; postscript files of 6 figures include
- …