sj-mp4-1-lan-10.1177_00236772231169344 - Supplemental material for Urinary bladder catheterisation of female pigs: Influence of bladder content and <i>Escherichia coli</i> urinary tract infection on procedural outcome

Supplemental material, sj-mp4-1-lan-10.1177_00236772231169344 for Urinary bladder catheterisation of female pigs: Influence of bladder content and Escherichia coli urinary tract infection on procedural outcome by Kristian Stærk, Louise Langhorn, Bo Halle and Thomas Emil Andersen in Laboratory Animals</p

Systemic thioridazine in combination with dicloxacillin against early aortic graft infections caused by <i>Staphylococcus aureus</i> in a porcine model: <i>In vivo</i> results do not reproduce the <i>in vitro</i> synergistic activity - Fig 2

<p><b>Changes in weight <b>(A)</b>, temperature <b>(B)</b>, white blood cell count (WBC) <b>(C)</b>, haemoglobin (HGB) <b>(D)</b>, and haptoglobin <b>(E)</b> of each treatment group during the experimental period are displayed as mean values with standard deviation bars at predefined time points.</b> Graft implantation and inoculation was at day -7 and the dotted grey line indicates treatment initiation at day 0. Dicloxacillin (DCX); Thioridazine (TDZ)</p

Primary bacteriological endpoints.

<p>Primary bacteriological endpoints.</p

<i>In vitro</i> viability assay: The effect of thioridazine (TDZ) and dicloxacillin (DCX), alone and in combination, on survival of MSSA (ATCC 29213) over time.

<p>Control: No drug.</p

Baseline characteristics, listed for all pigs and by treatment group.

<p>Baseline characteristics, listed for all pigs and by treatment group.</p

Mixed model analysis of longitudinal continuous outcomes.

<p>Mixed model analysis of longitudinal continuous outcomes.</p