21 research outputs found
The Chemical Compositions of the Type II Cepheids -- The BL Her and W Vir Variables
Abundance analyses from high-resolution optical spectra are presented for 19
Type II Cepheids in the Galactic field. The sample includes both short-period
(BL Her) and long-period (W Vir) stars. This is the first extensive abundance
analysis of these variables. The C, N, and O abundances with similar spreads
for the BL Her and W Vir show evidence for an atmosphere contaminated with
-process and CN-cycling products. A notable anomaly of the BL Her
stars is an overabundance of Na by a factor of about five relative to their
presumed initial abundances. This overabundance is not seen in the W Vir stars.
The abundance anomalies running from mild to extreme in W Vir stars but not
seen in the BL Her stars are attributed to dust-gas separation that provides an
atmosphere deficient in elements of high condensation temperature, notably Al,
Ca, Sc, Ti, and -process elements. Such anomalies have previously been seen
among RV Tau stars which represent a long-period extension of the variability
enjoyed by the Type II Cepheids. Comments are offered on how the contrasting
abundance anomalies of BL Her and W Vir stars may be explained in terms of the
stars' evolution from the blue horizontal branch.Comment: 41 pages including 11 figures and 4 tables; Accepted for publication
in Ap
Horizontal Branch Stars: The Interplay between Observations and Theory, and Insights into the Formation of the Galaxy
We review HB stars in a broad astrophysical context, including both variable
and non-variable stars. A reassessment of the Oosterhoff dichotomy is
presented, which provides unprecedented detail regarding its origin and
systematics. We show that the Oosterhoff dichotomy and the distribution of
globular clusters (GCs) in the HB morphology-metallicity plane both exclude,
with high statistical significance, the possibility that the Galactic halo may
have formed from the accretion of dwarf galaxies resembling present-day Milky
Way satellites such as Fornax, Sagittarius, and the LMC. A rediscussion of the
second-parameter problem is presented. A technique is proposed to estimate the
HB types of extragalactic GCs on the basis of integrated far-UV photometry. The
relationship between the absolute V magnitude of the HB at the RR Lyrae level
and metallicity, as obtained on the basis of trigonometric parallax
measurements for the star RR Lyrae, is also revisited, giving a distance
modulus to the LMC of (m-M)_0 = 18.44+/-0.11. RR Lyrae period change rates are
studied. Finally, the conductive opacities used in evolutionary calculations of
low-mass stars are investigated. [ABRIDGED]Comment: 56 pages, 22 figures. Invited review, to appear in Astrophysics and
Space Scienc
The Luminosities and Distance Scales of Type II Cepheid and RR Lyrae variables
Infrared and optical absolute magnitudes are derived for the type II Cepheids
kappa Pav and VY Pyx from revised Hipparcos parallaxes and for kappa Pav, V553
Cen and SW Tau from pulsation parallaxes. Phase-corrected JHK mags are given
for 142 RR Lyrae variables based on 2MASS data. RR Lyrae itself is overluminous
compared with LMC RR Lyraes at the classical Cepheid modulus (18.39) consistent
with a prediction of Catalan and Cortes. V553 Cen and SW Tau deviate by only
0.02 mag in the mean from the Matsunaga PL(K) relation for globular cluster
type II Cepheids with a zero-point based on the same LMC modulus. Comparing
directly these two stars with type II Cepheids in the LMC and in the Galactic
Bulge leads to an LMC modulus of 18.37\pm0.09 and a distance to the Galactic
Centre of 7.64\pm 0.21kpc. Kappa Pav may be a binary. V553 Cen and SW Tau show
that at optical wavelengths PL relations are wider for field stars than for
those in globular clusters (abridged).Comment: 29 pages, 13 figures, accepted for MNRA
Synthetic Nanoparticles for Vaccines and Immunotherapy
The immune system plays a critical role in our health. No other component of human physiology plays a decisive role in as diverse an array of maladies, from deadly diseases with which we are all familiar to equally terrible esoteric conditions: HIV, malaria, pneumococcal and influenza infections; cancer; atherosclerosis; autoimmune diseases such
as lupus, diabetes, and multiple sclerosis. The importance of understanding the function of the immune system and learning how to modulate immunity to protect against or treat disease thus cannot be overstated. Fortunately, we are entering an exciting era where the
science of immunology is defining pathways for the rational manipulation of the immune system at the cellular and molecular level, and this understanding is leading to dramatic advances in the clinic that are transforming the future of medicine.1,2 These initial advances are being made primarily through biologic drugs– recombinant proteins (especially antibodies) or patient-derived cell therapies– but exciting data from preclinical studies suggest that a marriage of approaches based in biotechnology with the materials science and chemistry of nanomaterials, especially nanoparticles, could enable more effective and safer immune engineering strategies. This review will examine these nanoparticle-based strategies to immune modulation in detail, and discuss the promise and outstanding challenges facing the field of immune engineering from a chemical biology/materials engineering perspectiveNational Institutes of Health (U.S.) (Grants AI111860, CA174795, CA172164, AI091693, and AI095109)United States. Department of Defense (W911NF-13-D-0001 and Awards W911NF-07-D-0004
Intercomparison of the Radio-Chronometric Ages of Plutonium-Certified Reference Materials with Distinct Isotopic Compositions
An intercomparison of the radio-chronometric ages of four distinct plutonium-certified reference materials varying in chemical form, isotopic composition, and period of production are presented. The cross-comparison of the different 234U/238Pu, 235U/239Pu, 236U/240Pu, and 241Am/241Pu model purification ages obtained at four independent analytical facilities covering a range of laboratory environments from bulk sample processing to clean facilities dedicated to nuclear forensic investigation of environmental samples enables a true assessment of the state-of-practice in “age dating capabilities” for nuclear materials. The analytical techniques evaluated used modern mass spectrometer instrumentation including thermal ionization mass spectrometers and inductively coupled plasma mass spectrometers for isotopic abundance measurements. Both multicollector and single collector instruments were utilized to generate the data presented here. Consensus values established in this study make it possible to use these isotopic standards as quality control standards for radio-chronometry applications. Results highlight the need for plutonium isotopic standards that are certified for 234U/238Pu, 235U/239Pu, 236U/240Pu, and 241Am/241Pu model purification ages as well as other multigenerational radio-chronometers such as 237Np/241Pu. Due to the capabilities of modern analytical instrumentation, analytical laboratories that focus on trace level analyses can obtain model ages with marginally larger uncertainties than laboratories that handle bulk samples. When isotope ratio measurement techniques like thermal ionization mass spectrometry and inductively coupled plasma mass spectrometry with comparable precision are utilized, model purification ages with similar uncertainties are obtained.JRC.G.II.6-Nuclear Safeguards and Forensic