2,669 research outputs found

    Men and women from the STRIDE clinical trial: An assessment of stimulant abstinence symptom severity at residential treatment entry

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    Background and Objectives Gender‐specific factors associated with stimulant abstinence severity were examined in a stimulant abusing or dependent residential treatment sample (N = 302). Method Bivariate statistics tested gender differences in stimulant abstinence symptoms, measured by participant‐reported experiences of early withdrawal. Multivariate linear regression examined gender and other predictors of stimulant abstinence symptom severity. Results Women compared to men reported greater stimulant abstinence symptom severity. Anxiety disorders and individual anxiety‐related abstinence symptoms accounted for this difference. African American race/ethnicity was predictive of lower stimulant abstinence severity. Discussion and Conclusions Women were more sensitive to anxiety‐related stimulant withdrawal symptoms. Scientific Significance Clinics that address anxiety‐related abstinence symptoms, which more commonly occur in women, may improve treatment outcome. (Am J Addict 2015;XX:XX –XX

    Digging for Dark Matter: Spectral Analysis and Discovery Potential of Paleo-Detectors

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    Paleo-detectors are a recently proposed method for the direct detection of Dark Matter (DM). In such detectors, one would search for the persistent damage features left by DM--nucleus interactions in ancient minerals. Initial sensitivity projections have shown that paleo-detectors could probe much of the remaining Weakly Interacting Massive Particle (WIMP) parameter space. In this paper, we improve upon the cut-and-count approach previously used to estimate the sensitivity by performing a full spectral analysis of the background- and DM-induced signal spectra. We consider two scenarios for the systematic errors on the background spectra: i) systematic errors on the normalization only, and ii) systematic errors on the shape of the backgrounds. We find that the projected sensitivity is rather robust to imperfect knowledge of the backgrounds. Finally, we study how well the parameters of the true WIMP model could be reconstructed in the hypothetical case of a WIMP discovery.Comment: 14 pages, 5 figures, code available at https://github.com/tedwards2412/paleo_detectors/ . v2: Added additional analysis theory details, matches version published in PR

    Economic pressure, parent personality and child development: an interactionist analysis

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    "Der gegenwärtige ökonomische Abschwung in den USA und auf der ganzen Welt hat wieder die Aufmerksamkeit auf die Prozesse gelenkt, durch die Familien und Kinder durch ökonomische Härten belastet sind. Diese Studie betrachtet die Reaktionen auf ökonomische Härten in einer Stichprobe von Erwachsenen, die zum ersten Mal vor 20 Jahren befragt wurden, als sie noch Jugendliche waren. Insgesamt 271 der ursprünglichen G2 Jugendlichen (Durchschnittsalter M = 25.6 Jahre) nahmen an dieser Studie zusammen mit ihren kleinen Kindern (G3, Durchschnittsalter M = 2.31 Jahre zum ersten Erhebungszeitpunkt) und, in 81% der Fälle, zusammen mit dem anderen Elternteil des Kindes. Die Datenanalysen folgten einem interaktionistischen Modell und gingen davon aus, dass positive Persönlichkeitseigenschaften im Jugendalter der G2 weniger ökonomische Belastungen im Erwachsenenalter vorhersagen würden. Gleichzeitig wurde erwartet, dass diese positiven Persönlichkeitseigenschaften die negativen Familienprozesse aufhalten würden, die eine kompetente Entwicklung in G3 wahrscheinlich behindern. Die Befunde waren mit dem Selektionsaspekt im interaktionistischen Modell konsistent. Das Model sagte darüber hinaus vorher, dass ökonomischen Belastungen und andere familienbezogene Stressprozesse die Entwicklung von G3 über die frühere G2 Persönlichkeit beeinflussten. Der Sozialisationsaspekt im interaktionistischen Modell erhielt also auch Unterstützung. Die Befunde sprechen dafür, dass die Beziehung zwischen den ökonomischen Bedingungen und der Entwicklung von Kindern einen dynamischen Prozess aus Selektion und Sozialisation darstellt, der über Zeit und über Generationen zum Tragen kommt." (Autorenreferat)"The current economic downturn in the U.S. and around the world has refocused attention on the processes through which families and children are affected by economic hardship. This study examines the response to economic pressure of a cohort of youth first studied 20 years ago as adolescents and now grown to adulthood. A total of 271 of the original G2 adolescents (M age = 25.6 years) participated in the study with their young child (G3, M age = 2.31 years at the first time of assessment) and the child's other parent in 81% of the cases. Data analyses were guided by the interactionist model which proposed that positive G2 personality attributes during adolescence would predict lower economic pressure during adulthood and would diminish the negative family processes related to economic pressure expected to disrupt competent G3 development. The findings were consistent with this social selection aspect of the interactionist model. The model also predicted that economic pressure and other aspects of the related family stress process would affect G3 development net of earlier G2 personality. This social causation aspect of the interactionist model also received support. The findings suggest that the relationship between economic conditions and child development reflect a dynamic process of selection and causation that plays out over time and generations." (author's abstract

    Medical Student Performance on the National Board of Medical Examiners Emergency Medicine Advanced Clinical Examination and the National Emergency Medicine M4 Exams

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    In April 2013, the National Board of Medical Examiners (NBME) released an Advanced Clinical Examination (ACE) in emergency medicine (EM). In addition to this new resource, CDEM (Clerkship Directors in EM) provides two online, high-quality, internally validated examinations. National usage statistics are available for all three examinations, however, it is currently unknown how students entering an EM residency perform as compared to the entire national cohort. This information may help educators interpret examination scores of both EM-bound and non-EM-bound students. Objectives The objective of this study was to compare EM clerkship examination performance between students who matched into an EM residency in 2014 to students who did not. We made comparisons were made using the EM-ACE and both versions of the National fourth year medical student (M4) EM examinations. Method In this retrospective multi-institutional cohort study, the EM-ACE and either Version 1 (V1) or 2 (V2) of the National EM M4 examination was given to students taking a fourth-year EM rotation at five institutions between April 2013 to February 2014. We collected examination performance, including the scaled EM-ACE score, and percent correct on the EM M4 exams, and 2014 NRMP Match status. Student t-tests were performed on the examination averages of students who matched in EM as compared with those who did not. Results A total of 606 students from five different institutions took both the EM-ACE and one of the EM M4 exams; 94 (15.5%) students matched in EM in the 2014 Match. The mean score for EM-bound students on the EM-ACE, V1 and V2 of the EM M4 exams were 70.9 (n=47, SD=9.0), 84.4 (n=36, SD=5.2), and 83.3 (n=11, SD=6.9), respectively. Mean scores for non-EM-bound students were 68.0 (n=256, SD=9.7), 82.9 (n=243, SD=6.5), and 74.5 (n=13, SD=5.9). There was a significant difference in mean scores in EM-bound and non-EM-bound student for the EM-ACE (p=0.05) and V2 (p<0.01) but not V1 (p=0.18) of the National EM M4 examination. Conclusion Students who successfully matched in EM performed better on all three exams at the end of their EM clerkship
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