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Lagrangian perturbations and the matter bispectrum I: fourth-order model for non-linear clustering
We investigate the Lagrangian perturbation theory of a homogeneous and
isotropic universe in the non-relativistic limit, and derive the solutions up
to the fourth order. These solutions are needed for example for the
next-to-leading order correction of the (resummed) Lagrangian matter
bispectrum, which we study in an accompanying paper. We focus on flat
cosmologies with a vanishing cosmological constant, and provide an in-depth
description of two complementary approaches used in the current literature.
Both approaches are solved with two different sets of initial conditions---both
appropriate for modelling the large-scale structure. Afterwards we consider
only the fastest growing mode solution, which is not affected by either of
these choices of initial conditions. Under the reasonable approximation that
the linear density contrast is evaluated at the initial Lagrangian position of
the fluid particle, we obtain the nth-order displacement field in the so-called
initial position limit: the nth order displacement field consists of 3(n-1)
integrals over n linear density contrasts, and obeys self-similarity. Then, we
find exact relations between the series in Lagrangian and Eulerian perturbation
theory, leading to identical predictions for the density contrast and the
peculiar-velocity divergence up to the fourth order.Comment: 31 pages, matches published version in JCAP, added an extra section
which discusses and motivates the choice of initial conditions, extended the
title for the sake of precisio
A formal theory for spatial representation and reasoning in biomedical ontologies
Objective: The objective of this paper is to demonstrate how a
formal spatial theory can be used as an important tool for
disambiguating the spatial information embodied in biomedical
ontologies and for enhancing their automatic reasoning capabilities.
Method and Materials: This paper presents a formal theory of parthood
and location relations among individuals, called Basic Inclusion
Theory (BIT). Since biomedical ontologies are comprised of assertions
about classes of individuals (rather than assertions about individuals),
we define parthood and location relations among classes in the
extended theory BIT+Cl (Basic Inclusion Theory for Classes). We
then demonstrate the usefulness of this formal theory for making
the logical structure of spatial information more precise in two
ontologies concerned with human anatomy: the Foundational Model of
Anatomy (FMA) and GALEN.
Results: We find that in both the FMA and GALEN, class-level spatial
relations with different logical properties are not always explicitly
distinguished. As a result, the spatial information included in
these biomedical ontologies is often ambiguous and the possibilities
for implementing consistent automatic reasoning within or across
ontologies are limited.
Conclusion: Precise formal characterizations of all spatial relations
assumed by a biomedical ontology are necessary to ensure that the
information embodied in the ontology can be fully and coherently
utilized in a computational environment. This paper can be seen as
an important beginning step toward achieving this goal, but much
more work is along these lines is required
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