The Internal Proper Motions Of Stars In The Open Cluster M35

Relative proper motions, based on 108 orbits of Hubble Space Telescope Fine Guidance Sensor data extending from 1992 to 2006, are reported for 74 stars in the open cluster M35 (NGC 2168). A subset of 22 of these objects are then used to compute the cluster's internal proper motion dispersions in both right ascension and declination. We find that these dispersions are equal to within their measurement errors. The average one-dimensional dispersion is 0.018 +/- 0.002 arcsec century(-1). When combined with the M35 radial velocity dispersion of 0.65 +/- 0.10 km s(-1) found by Geller et al., this produces a cluster distance of 762 +/- 145 pc. Using isochrone fits to the cluster main sequence, this distance suggests that M35 has an age of about 133 Myr. Although this age is consistent with that typically found for M35, the formal error in the dynamical distance of +/- 19% can accommodate ages between 65 Myr and 201 Myr.McDonald Observator

Long-term results of cyclosporine-steroid therapy in 131 non-matched cadaveric renal transplants.

One-hundred-and-twenty-eight recipients of 131 consecutive, non-matched cadaver renal allografts were treated with cyclosporine and steroids. They have been followed for 4 to 6 yr. Cumulative patient survival at 1-yr was 92.2% and at 6yr it is 77.8%. Cumulative graft survival at 1-yr was 79.4% and at 6 yr it is 50.0%. After the high-risk 1st yr, the rate of graft loss was even and similar to that reported after the 1st yr for grafts treated with azathioprine and steroids. This indicates that cyclosporine nephrotoxicity has not had an obvious adverse effect on the survival of chronically functioning grafts. The results were better with primary grafting versus retransplantation, but were not significantly influenced by age, diabetes mellitus, or a delayed switch in patients from cyclosporine to azathioprine. We have concluded that cyclosporine-steroid therapy is safe and effective for long-term use after cadaveric renal transplantation

Mini black holes at the LHC : discovery through di-jet suppression, mono-jet emission and a supersonic boom in the quark-gluon plasma in ALICE, ATLAS and CMS

We examine experimental signatures of TeV-mass black hole formation in heavy ion collisions at the LHC. We find that the black hole production results in a complete disappearance of all very high p_T (> 500 GeV) back-to-back correlated di-jets of total mass M > M_f ~ 1 TeV. We show that the subsequent Hawking-decay produces multiple hard mono-jets and discuss their detection. We study the possibility of cold black hole remnant (BHR) formation of mass ~ M_f and the experimental distinguishability of scenarios with BHRs and those with complete black hole decay. Finally we point out that a Heckler-Kapusta-Hawking plasma may form from the emitted mono-jets. In this context we present new simulation data of Mach shocks and of the evolution of initial conditions until the freeze-out

Sense of Place: American Regional Cultures

Despite the homogenization of American life, areas of strong regional consciousness still persist in the United States, and there is a growing interest in regionalism among the public and among academics. In response to that interest ten folklorists here describe and interpret a variety of American regional cultures in the twentieth century. Their book is the first to deal specifically with regional culture and the first to employ the perspective of folklore in the study of regional identity and consciousness. The authors range widely over the United States, from the Eastern Shore to the Pacific Northwest, from the Southern Mountains to the Great Plains. They look at a variety of cultural expressions and practices—legends, anecdotes, songs, foodways, architecture, and crafts. Tying their work together is a common consideration of how regional culture shapes and is shaped by the consciousness of living in a special place. In exploring this dimension of regional culture the authors consider the influence of natural environment and historical experience on the development of regional culture, the role of ethnicity in regional consciousness, the tensions between insiders and outsiders that stem from a sense of regional identity, and the changes in culture in response to social and economic change. With its focus on cultural manifestations and its folkloristic perspective this book provides a fresh and needed contribution to regional studies. Writ¬ten in a clear, readable style, it will appeal to general readers interested in American regions and their cultures. At the same time the research and analytical approach make it useful not only to folklorists but to cultural geographers, anthropologists, and other scholars of regional studies. Barbara Allen is chair of the Department of American Studies at the University of Notre Dame. Thomas J. Schlereth is professor of American studies at the University of Notre Dame. Presents valuable work on parts of the U.S. that are somewhat sparsely represented in folklore publications. —Choice Reinforces what we may have already expected—that the folk region lies in the mind and spirit as much as in physical boundaries. —South Bend Tribunehttps://uknowledge.uky.edu/upk_folklore/1008/thumbnail.jp

Phage ϕC2 mediates transduction of Tn6215, encoding erythromycin resistance, between Clostridium difficile strains

UNLABELLED: In this work, we show that Clostridium difficile phage ϕC2 transduces erm(B), which confers erythromycin resistance, from a donor to a recipient strain at a frequency of 10(-6) per PFU. The transductants were lysogenic for ϕC2 and contained the erm(B) gene in a novel transposon, Tn6215. This element is 13,008 bp in length and contains 17 putative open reading frames (ORFs). It could also be transferred at a lower frequency by filter mating. IMPORTANCE: Clostridium difficile is a major human pathogen that causes diarrhea that can be persistent and difficult to resolve using antibiotics. C. difficile is potentially zoonotic and has been detected in animals, food, and environmental samples. C. difficile genomes contain large portions of horizontally acquired genetic elements. The conjugative elements have been reasonably well studied, but transduction has not yet been demonstrated. Here, we show for the first time transduction as a mechanism for the transfer of a novel genetic element in C. difficile. Transduction may also be a useful tool for the genetic manipulation of C. difficile.Peer reviewe

The habitability of stagnant-lid Earths around dwarf stars

The habitability of a planet depends on various factors, such as delivery of water during the formation, the co-evolution of the interior and the atmosphere, as well as the stellar irradiation which changes in time. Since an unknown number of rocky exoplanets may operate in a one-plate convective regime, i.e., without plate tectonics, we aim at understanding under which conditions planets in such a stagnant-lid regime may support habitable surface conditions. Understanding the interaction of the planetary interior and outgassing of volatiles with the atmosphere in combination with the evolution of the host star is crucial to determine the potential habitability. M-dwarf stars in particular possess a high-luminosity pre-main sequence phase which endangers the habitability of planets around them via water loss. We therefore explore the potential of secondary outgassing from the planetary interior to rebuild a water reservoir allowing for habitability at a later stage. We compute the boundaries of the habitable zone around M, K, G, and F-dwarf stars using a 1D cloud-free radiative-convective climate model accounting for the outgassing history of CO2 and H2O from an interior evolution and outgassing model for different interior compositions and stellar luminosity evolutions. The outer edge of the habitable zone strongly depends on the amount of CO2 outgassed from the interior, while the inner edge is mainly determined via the stellar irradiation, as soon as a sufficiently large water reservoir has been outgassed. A build-up of a secondary water reservoir for planets around M-dwarf stars is possible even after severe water loss during the high luminosity pre-main sequence phase as long as some water has been retained within the mantle. Earth-like stagnant-lid planets allow for habitable surface conditions within a continuous habitable zone that is dependent on interior composition.Comment: 15 pages, accepted by A&A, abstract shortene

Valuing Breastfeeding: Health Care Professionals’ Experiences of Delivering a Conditional Cash Transfer Scheme for Breastfeeding in Areas With Low Breastfeeding Rates

Alongside a randomized controlled trial testing the effectiveness of offering a cash transfer scheme (shopping vouchers) to mothers in areas with low breastfeeding rates, qualitative interviews were conducted with health care professionals delivering the scheme to explore their experiences. Health care professionals (n = 34; mainly midwives and health visitors) were interviewed in depth. Transcripts from recorded interviews were analyzed using a Framework Analysis approach. There was widespread acceptance of the scheme by health care professionals, with prior concerns regarding bribery and coercion being quickly allayed. Health care professionals reported that the scheme fitted in well with their routine ways of promoting and endorsing breastfeeding. They described their experiences of women’s positive reaction toward the scheme and how the scheme encouraged breastfeeding and gave breastfeeding higher value. Health care professionals reported that the incentives helped them engage women and promote and support breastfeeding in areas with low breastfeeding rates

VA Accountability Act of 2015 (H.R. 1994), as Reported to the House

[Excerpt] This report describes the VA Accountability Act of 2015 (H.R. 1994) as reported to the House by the Committee on Veterans Affairs on July 23 2015 and compares it to current law where appropriate. A press account has reported that Chairman Jeff Miller may meet with all committee members to seek views of the minority before floor action. As a result of this meeting, it is possible that the final bill that will go to the House floor may have some provisions that differ from those that the Committee reported. This report provides a section-by-section description of the act

2-D and 3-D Radiation Transfer Models of High-Mass Star Formation

2-D and 3-D radiation transfer models of forming stars generally produce bluer 1-10 micron colors than 1-D models of the same evolutionary state and envelope mass. Therefore, 1-D models of the shortwave radiation will generally estimate a lower envelope mass and later evolutionary state than multidimensional models. 1-D models are probably reasonable for very young sources, or longwave analysis (wavelengths > 100 microns). In our 3-D models of high-mass stars in clumpy molecular clouds, we find no correlation between the depth of the 10 micron silicate feature and the longwave (> 100 micron) SED (which sets the envelope mass), even when the average optical extinction of the envelope is >100 magnitudes. This is in agreement with the observations of Faison et al. (1998) of several UltraCompact HII (UCHII) regions, suggesting that many of these sources are more evolved than embedded protostars. We have calculated a large grid of 2-D models and find substantial overlap between different evolutionary states in the mid-IR color-color diagrams. We have developed a model fitter to work in conjunction with the grid to analyze large datasets. This grid and fitter will be expanded and tested in 2005 and released to the public in 2006.Comment: 10 pages, 8 figures, to appear in the proceedings of IAU Symp 227, Massive Star Birth: A Crossroads of Astrophysics, (Cesaroni R., Churchwell E., Felli M., Walmsley C. editors