Stepwise regression analysis of variables influencing CPAP adherence.

<p>Abbreviations: CPAP, continuous positive airway pressure; AHI, apnea-hypopnea index;</p><p>CPAP adherence: CPAP use ≥4 h/night.</p><p>Significant level for p value: <0.05.</p><p>Area under the ROC: 0.607.</p

Baseline characteristics of adherent and non-adherent patients.^*

<p>*Results presented as mean (standard deviation) unless otherwise indicated.</p><p>Adherent patients: continuous positive airway pressure (CPAP) use ≥4 h/night.</p><p>Non-adherent patients: CPAP refused or abandoned, or CPAP use<4 h/night.</p><p>Significant level for p value: <0.05.</p

Flow diagram of subjects during the study.

<p>Abbreviations: CPAP: continuous positive airway pressure; IRSR, Institut de Recherche en Santé Respiratoire des Pays de la Loire.</p

Multivariate adjusted Odds Ratio (OR) (95% confidence interval [CI]) for hypertension associated with sleep duration in the whole obstructive sleep apnea (OSA) group and in the 2 categories of OSA severity.

<p>SDB, sleep-disordered breathing.</p><p>OR were adjusted for age, gender, obesity, diabetes, depression, current smoking, use of thyroid hormones, excessive daytime sleepiness, poor sleep, time spent in slow wave sleep, overall arousal index, time in bed, and study site.</p><p>* p<0.05.</p><p>**p<0.01.</p><p>Multivariate adjusted Odds Ratio (OR) (95% confidence interval [CI]) for hypertension associated with sleep duration in the whole obstructive sleep apnea (OSA) group and in the 2 categories of OSA severity.</p

Multivariate adjusted odds ratio (OR) (95% confidence interval [CI]) for hypertension associated with sleep-disordered breathing or sleep duration.

<p>OSA, obstructive sleep apnea.</p><p>Model 1 included OSA severity or sleep duration adjusted for age, gender, obesity, diabetes, depression, current smoking, use of thyroid hormones, excessive daytime sleepiness, poor sleep, time spent in slow wave sleep, overall arousal index, time in bed, and study site.</p><p>Model 2 included OSA severity or sleep duration adjusted for age, gender, obesity, diabetes, depression, current smoking, use of thyroid hormones, excessive daytime sleepiness, poor sleep, time spent in slow wave sleep, overall arousal index, sleep latency, and study site.</p><p>Model 3 included OSA severity or sleep duration adjusted for age, gender, obesity, diabetes, depression, current smoking, use of thyroid hormones, excessive daytime sleepiness, poor sleep, time spent in slow wave sleep, overall arousal index, wake time after sleep onset, and study site.</p><p>Adjusted OR were all statistically significant with p value <0.01</p>†<p>Tested by the Cochrane-Armitage trend test.</p><p>Multivariate adjusted odds ratio (OR) (95% confidence interval [CI]) for hypertension associated with sleep-disordered breathing or sleep duration.</p

Characteristics of the study population.

<p>Data are expressed as mean (SD) or percentages.</p><p>HTN, hypertension; BMI, body mass index; EDS, excessive daytime sleepiness; WASO, wake time after sleep onset; REM, rapid eye movement; SW, slow wave.</p><p>Characteristics of the study population.</p