Pd-Catalyzed Cross-Coupling of Potassium Alkenyltrifluoroborates with 2‑Chloroacetates and 2‑Chloroacetamides

A protocol for the stereocontrolled synthesis of (<i>E</i>)- and (<i>Z</i>)-β,γ-unsaturated esters and amides is reported. 2-Chloroacetates as well as secondary and tertiary 2-chloroacetamides were successfully employed as electrophiles in the Suzuki–Miyaura cross-coupling reaction with potassium (<i>E</i>)- and (<i>Z</i>)-alkenyltrifluoroborates, affording the corresponding products in high yield

Kinetic growth curve of the <i>Trichomonas vaginalis</i> 30236 isolate after exposure to EOP at 500 μg/mL for 1 h, 6 h, 12 h, 24 h, 48 h, 72 h and 96 h.

<p>Data represent mean ± standard deviation of at least three experiments, all in triplicate. Different letters indicate a significant difference (p < 0.05).</p

CHO-K1 cell viability after treatment with different concentrations of EOP.

<p>Cell proliferation in CHO-K1 was investigated by the MTT assay, and metronidazole was used as a positive control. Data are expressed as the mean ± SEM of the viabilities of CHO-K1 cells in three independent experiments. (*) indicates a difference between the treatments in CHO-K1 cells. The differences were considered significant at p < 0.05. VC = vehicle control; MTZ = metronidazole.</p

Volatile compounds identified by gas chromatography followed by mass spectrometry (GC-MS) of the Brazilian red propolis essential oil.

<p>Volatile compounds identified by gas chromatography followed by mass spectrometry (GC-MS) of the Brazilian red propolis essential oil.</p

Anti-rCP40 total IgG (4A), IgG1 (4B) and IgG2a (4C) levels in immunized mice treated with EOP and recombinant endoglycosidase CP40 from <i>C</i>. <i>pseudotuberculosis</i> (rCP40), either separately or together.

<p>Measurements were taken on day 0 and then 21 and 42 days post-immunization. Data represent means ± standard deviations of IgG levels in the sera collected from 6 animals/group. Different letters in the same experimental day indicate a significant difference (p < 0.05).</p