2 research outputs found
Resuscitation outcomes comparing year 2000 with year 2005 ALS guidelines in a pig model of cardiac arrest
Background: Ventricutar fibrillation remains the leading cause of death
in western societies. International organizations publish guidelines to
follow in case of cardiac arrest. The aim of the present study is to
assess whether the newly published guidelines record similar
resuscitation success with the 2000 Advanced Life Support Guidelines on
Resuscitation in a swine mode( of cardiac arrest.
Methods and results: Nineteen landrace/large white pigs were used.
Ventricular fibrillation was induced with the use of a transvenous
pacing wire inserted into the right ventricle. The animals were
randomized into two groups. In Group A, 10 animals were resuscitated
using the 2000 guidelines, whereas in Group B, 9 animals were
resuscitated using the 2005 guidelines. Both algorithms recorded similar
successful resuscitation rates, as 60% of the animals in Group A and
44.5% in Group B were successfulty resuscitated. However, animals in
Group A restored a rhythm, compatible with a pulse, quicker than those
in Group B (p = 0.002). Coronary perfusion pressure (CPP) was not
adversely affected by three defibrillation attempts in Group A.
Conclusions: Both algorithms’ resulted in comparable resuscitation
success, however, guidelines 2000 resulted in faster resuscitation
times. These preliminary results merit further investigation. (c) 2006
Elsevier Ireland Ltd. All rights reserved