Pre-/perinatal reduced optimality and neurodevelopment at 1 month and 3 years of age : Results from the Japan Environment and Children’s Study (JECS)

Acknowledgments The authors thank the JECS participants and the JECS Group as well as Nagamasa Maeda, Mikiya Fujieda, Naomi Mitsuda, and Atsuko Mori of the Kochi Regional Centre of the JECS and Sifa Marie Joelle Muchanga of the National Center for Global Health and Medicine. The members of the JECS Group as of 2022 are as follows: Michihiro Kamijima (principal investigator, Nagoya City University, Nagoya, Japan, [email protected]), Shin Yamazaki (National Institute for Environmental Studies, Tsukuba, Japan), Yukihiro Ohya (National Center for Child Health and Development, Tokyo, Japan), Reiko Kishi (Hokkaido University, Sapporo, Japan), Nobuo Yaegashi (Tohoku University, Sendai, Japan), Koichi Hashimoto (Fukushima Medical University, Fukushima, Japan), Chisato Mori (Chiba University, Chiba, Japan), Shuichi Ito (Yokohama City University, Yokohama, Japan), Zentaro Yamagata (Universit y of Yamanashi, Chuo, Japan), Hidekuni Inadera (University of Toyama, Toyama, Japan), Takeo Nakayama (Kyoto University, Kyoto, Japan), Tomotaka Sobue (Osaka University, Suita, Japan), Masayuki Shima (Hyogo Medical University, Nishinomiya, Japan), Hiroshige Nakamura(Tottori University, Yonago, Japan), Narufumi Suganuma (Kochi University, Nankoku, Japan), Koichi Kusuhara (University of Occupational and Environmental Health, Kitakyushu, Japan), and Takahiko Katoh (Kumamoto University, Kumamoto, Japan). Funding: The Japan Environment and Children’s Study (JECS) is funded by the Ministry of the Environment (MOE) of Japan, including data collection. The present study utilized part of the JECS data. However, for this particular study “Pre-/perinatal reduced optimality and neurodevelopment at 1 month and 3 years of age – Results from the Japan Environment and Children’s Study (JECS)”, the funder had no role in study design, analysis, decision to publish, or preparation of the manuscript.Peer reviewedPublisher PD

Development of a new screening tool for neuromotor development in children aged two – the neuromotor 5 min exam 2-year-old version (N5E2)

Acknowledgement This study is a part of the project related to the Japan Environment and Children’s Study (JECS) that is conducted and funded by the Ministry of Environment of Japan.Peer reviewedPostprin

Vitamin D deficiency associated with neurodevelopmental problems in 2-year-old Japanese boys

Acknowledgements The authors thank the JECS participants, as well as Nagamasa Maeda and Mikiya Fujieda of the Kochi Regional Centre of the JECS, and Ingrid Vinsa at the Gillberg Neuropsychiatry Centre. Funding information The Japan Environment and Children's Study was funded by the Ministry of Environment, JapanPeer reviewe

Chocolate consumption and risk of gestational diabetes mellitus: the Japan Environment and Children’s Study

The association of chocolate consumption with risk of gestational diabetes has not been examined. We aimed to investigate the prospective association between chocolate consumption and risk of gestational diabetes in a large birth cohort in Japan. A total of 97 454 pregnant women with a median gestational age of 12 weeks were recruited from January 2011 to March 2014. Data on demographic information, disease history, socio-economic status, lifestyle and dietary habits were obtained at the study enrolment. Dietary intake during the past 12 months before study enrolment was assessed through a semi-quantitative FFQ. The logistic regression was used to obtain the OR of gestational diabetes in relation to chocolate consumption. Among 84 948 women eligible for the analysis, 1904 cases of gestational diabetes (2·2 %) were identified during the period of pregnancy. After controlling for potential confounding factors including age, smoking status, drinking status, education level, occupation, pre-pregnant BMI, depression, previous history of macrosomia babies, parity, physical activity and dietary factors, women in the highest quartile of chocolate consumption, compared with those in the lowest quartile, had a significantly lower risk of developing gestational diabetes (OR 0·78, 95 % CI 0·67, 0·90; P for trend = 0·002). Stratified analyses suggested that the association was not significantly modified by pre-pregnancy BMI, age, parity, smoking status or drinking status. The present prospective cohort study provided evidence that chocolate consumption was associated with a significant lower risk of gestational diabetes in Japanese women

Association between pesticide usage during pregnancy and neonatal hyperbilirubinemia requiring treatment: the Japan Environment and Children's Study (母体の妊娠中の殺虫剤・防虫剤の使用と、治療を要する新生児高ビリルビン血症との関連)

信州大学(Shinshu university)博士（医学）雑誌に発表。 / Pediatric Research 89(6) :1565-1570(2021); doi:10.1038/s41390-020-1100-6. ©　2021 Springer Nature LimitedThesis柴崎 拓実. Association between pesticide usage during pregnancy and neonatal hyperbilirubinemia requiring treatment: the Japan Environment and Children's Study (母体の妊娠中の殺虫剤・防虫剤の使用と、治療を要する新生児高ビリルビン血症との関連). 信州大学, 2021, 博士論文. 博士（医学）, 甲第1243号, 令和03年03月31日授与.doctoral thesi

Effect of pro-inflammatory diet before pregnancy on gestational age and birth weight: The Japan Environment and Children's Study

博士（医学）福島県立医科大

Impact of longer working hours on fathers’ parenting behavior when their infants are 6 months old: The Japan Environment and Children’s Study

ObjectiveLong working hours have been suggested to affect fathers’ parenting behavior, but previously reported findings have been inconsistent. This study examined the association between the working hours and parenting behavior of fathers while accounting for other factors related to their parenting behavior, using data from the Japan Environment and Children Study (JECS), a large cohort study in Japan.MethodsData from 43,159 father–mother pairs were analyzed. The mother assessed the father’s frequency of seven parenting behaviors at 6 months after delivery. Then, each behavior was classified into a high-engagement group (always and sometimes) or a low-engagement group (rarely and never). The father’s weekly working hours was obtained from his responses and was classified into six levels.ResultsLogistic regression analysis showed that after adjustment for covariates, fathers’ weekly working hours was inversely associated with the frequency of all parenting behaviors examined in this study (p for trend <0.0001). Compared with fathers working ≥0 to ≤40 h per week, those working >65 h per week showed the following adjusted odds ratios (95% confidence intervals) for low engagement in parenting behaviors: playing at home, 2.38 (2.08–2.72); changing diapers, 2.04 (1.89–2.20); and bathing the child, 2.01 (1.84–2.18).ConclusionThis study suggests that the greater time constraints imposed by longer working hours constitute a major factor that discourages fathers from engaging in childrearing behavior. Intervention targeting long working hours could contribute to measures aimed at promoting high-engagement parenting behaviors among fathers