Requirements for digitized aircraft spotting (Ouija) board for use on U.S. Navy aircraft carriers

This thesis will evaluate system and process elements to initiate requirements modeling necessary for the next generation Digitized Aircraft Spotting (Ouija) Board for use on U.S. Navy aircraft carriers to track and plan aircraft movement. The research will examine and evaluate the feasibility and suitability of transforming the existing two-dimensional static board to an electronic, dynamic display that will enhance situational awareness by using sensors and system information from various sources to display a comprehensive operational picture of the current flight and hangar decks aboard aircraft carriers. The authors will evaluate the current processes and make recommendations on elements the new system would display. These elements include what information is displayed, which external systems feed information to the display, and how intelligent agents could be used to transform the static display to a powerful decision support tool. Optimally, the Aircraft Handler will use this system to effectively manage the Flight and Hangar decks to support the projection of air power from U.S. aircraft carriers.http://archive.org/details/requirementsford109454447Lieutenant Commander, United States NavyLieutenant Commander, United States Navy ReserveApproved for public release; distribution is unlimited

Experimental Study of Operating Wireless Peer-To-Peer Collaborative Networks

Proceedings of the Tenth International Conference on Telecommunication Systems Modeling and Analysis October 3-6, 2002 Monterey, CaliforniaThe implications of using peer-to-peer communications within an urban environment are significant for Military applications. From a networking perspective, the use of wireless technologies to support the collaboration may have impacts on bandwidth and spectrum utilization. This paper explores the effects of wireless peer-to-peer (P2P) network behavior on the performance of collaboration support applications. The results achieved during the limited objective experiment conducted by the Naval Postgraduate School demonstrate significant affects of roaming on application sharing performance and integration with clientserver applications. We discuss the wireless network operation challenges leading to the solutions for scaling up application sharing and improving collaborators self-organizing behavior

A Limited Objective Experiment on Wireless Peer-To-Peer Collaborative Networking

The implications of using peer-to-peer communications within an urban environment are significant for military applications. From a networking perspective, the use of wireless technologies to support collaborative communications may have impacts on bandwidth and spectrum utilization. This paper explores the effects of wireless peer-to-peer (P2P) network behavior on the performance of collaboration support applications. The results achieved during the limited objective experiment conducted by the Naval Postgraduate School demonstrate significant effects of roaming on application-sharing performance and integration with client-server applications. The authors discuss the wireless network operation challenges leading to the solutions for scaling up application-sharing and improving collaborators' self-organizing behavior

Protection against Hemorrhagic Colitis in an Animal Model by Oral Immunization with Isogeneic Rabbit Enteropathogenic Escherichia coli Attenuated by Truncating Intimin

Strains of Shiga toxin (Stx)-producing Escherichia coli, also called enterohemorrhagic E. coli (EHEC), are important food-borne pathogens for humans. Most EHEC strains intimately adhere to the intestinal mucosa in a characteristic attaching and effacing (A/E) pattern, which is mediated by the bacterial adhesin intimin. Subsequent release of Stx1 and/or Stx2 leads to the frequent development of hemorrhagic colitis and, less commonly, to hemolytic-uremic syndrome. The aim of the present study was to develop an attenuated A/E E. coli strain for use as a vaccine against EHEC infection encoding a truncated intimin lacking adhesive capacity, but which would still express somatic antigens, other products of the locus of enterocyte effacement pathogenicity island, and an immunogenic remnant of the intimin molecule. A single-nucleotide deletion was generated in the eae gene in the prototype rabbit A/E E. coli strain RDEC-1 (O15:H−), which resulted in truncation of intimin by 81 C-terminal residues (860 to 939 amino acids) containing a disulfide loop. Inoculation of rabbits with large doses of the truncated intimin mutant (RDEC-1Δeae(860-939)) was well tolerated, as observed by the absence of clinical signs of disease or evidence of intestinal A/E lesions. The efficacy of RDEC-1Δeae(860-939) as a vaccine was evaluated by orogastric inoculation of rabbits with RDEC-1Δeae(860-939) followed by challenge with the virulent strain RDEC-H19A, an Stx1-producing derivative of wild-type RDEC-1 capable of inducing hemorrhagic colitis in rabbits. Following RDEC-H19A challenge, nonimmunized control rabbits exhibited characteristic weight loss with watery to bloody diarrhea and demonstrated intimate bacterial attachment, effacement of microvilli, submucosal edema, mucosal heterophile infiltrates, and Shiga toxin-induced vascular lesions. In contrast, the RDEC-1Δeae(860-939)-immunized rabbits showed no clinical signs of disease, maintained normal weight gain, had reduced fecal shedding of challenge organisms, and showed an absence of gross or microscopic lesions in the intestinal mucosa. Serum antibodies specific to intimin were detected among rabbits immunized with RDEC-1Δeae(860-939), indicating that truncation of the intimin functional domain not only attenuated bacterial virulence, but also retained at least some of the immunogenicity of native intimin. Although it is not possible to gauge the exact contribution of residual intimin immunity to protection, this attenuation strategy for A/E E. coli strains shows promise for the development of effective vaccines to prevent EHEC infection in humans and animals