Offspring of parents with recurrent depression: which features of parent depression index risk for offspring psychopathology?

Background: Parental depression is associated with an increased risk of psychiatric disorder in offspring, although outcomes vary. At present relatively little is known about how differences in episode timing, severity, and course of recurrentdepression relate to risk in children. The aim of this study was to consider the offspring of parents with recurrentdepression and examine whether a recent episode of parental depressionindexesrisk for offspringpsychopathology over and above these other parental depressionfeatures. <p/>Methods: Three hundred and thirty seven recurrently depressed parents and their offspring (aged 9–17) were interviewed as part of an ongoing study, the ‘Early Prediction of Adolescent Depression Study’. The Child and Adolescent Psychiatric Assessment was used to assess two child outcomes; presence of a DSM-IV psychiatric disorder and number of DSM-IV child-rated depression symptoms. <p/>Results: Children whose parents had experienced a recent episode of depression reported significantly more depression symptoms, and odds of child psychiatric disorder were doubled relative to children whose parents had not experienced a recent episode of depression. Past severity of parental depression was also significantly associated with child depression symptoms. <p/>Limitations: Statistical analyses preclude causal conclusions pertaining to parental depression influences on offspringpsychopathology; several features of parental depression were recalled retrospectively. <p/>Conclusions: This study suggests that particular features of parental depression, specifically past depression severity and presence of a recent episode, may be important indicators of risk for child psychiatric disorder and depressive symptoms

'The risks of playing it safe': a prospective longitudinal study of response to reward in the adolescent offspring of depressed parents

BACKGROUND Alterations in reward processing may represent an early vulnerability factor for the development of depressive disorder. Depression in adults is associated with reward hyposensitivity and diminished reward seeking may also be a feature of depression in children and adolescents. We examined the role of reward responding in predicting depressive symptoms, functional impairment and new-onset depressive disorder over time in the adolescent offspring of depressed parents. In addition, we examined group differences in reward responding between currently depressed adolescents, psychiatric and healthy controls, and also cross-sectional associations between reward responding and measures of positive social/environmental functioning. Method We conducted a 1-year longitudinal study of adolescents at familial risk for depression (n = 197; age range 10-18 years). Reward responding and self-reported social/environmental functioning were assessed at baseline. Clinical interviews determined diagnostic status at baseline and at follow-up. Reports of depressive symptoms and functional impairment were also obtained. RESULTS Low reward seeking predicted depressive symptoms and new-onset depressive disorder at the 1-year follow-up in individuals free from depressive disorder at baseline, independently of baseline depressive symptoms. Reduced reward seeking also predicted functional impairment. Adolescents with current depressive disorder were less reward seeking (i.e. bet less at favourable odds) than adolescents free from psychopathology and those with externalizing disorders. Reward seeking showed positive associations with social and environmental functioning (extra-curricular activities, humour, friendships) and was negatively associated with anhedonia. There were no group differences in impulsivity, decision making or psychomotor slowing. CONCLUSIONS Reward seeking predicts depression severity and onset in adolescents at elevated risk of depression. Adaptive reward responses may be amenable to change through modification of existing preventive psychological interventions

Affective bias and current, past and future adolescent depression: A familial high risk study.

Affective bias is a common feature of depressive disorder. However, a lack of longitudinal studies means that the temporal relationship between affective bias and depression is not well understood. One group where studies of affective bias may be particularly warranted is the adolescent offspring of depressed parents, given observations of high rates of depression and a severe and impairing course of disorder in this group

Secrecy fairness aware NOMA for untrusted users

Spectrally-efficient secure non-orthogonal multiple access (NOMA) has recently attained a substantial research interest for fifth generation development. This work explores crucial security issue in NOMA which is stemmed from utilizing the decoding concept of successive interference cancellation. Considering untrusted users, we design a novel secure NOMA transmission protocol to maximize secrecy fairness among users. A new decoding order for two users' NOMA is proposed that provides positive secrecy rate to both users. Observing the objective of maximizing secrecy fairness between users under given power budget constraint, the problem is formulated as minimizing the maximum secrecy outage probability (SOP) between users. In particular, closed-form expressions of SOP for both users are derived to analyze secrecy performance. SOP minimization problems are solved using pseudoconvexity concept, and optimized power allocation (PA) for each user is obtained. Asymptotic expressions of SOPs, and optimal PAs minimizing these approximations are obtained to get deeper insights. Further, globally-optimized power control solution from secrecy fairness perspective is obtained at a low computational complexity and, asymptotic approximation is obtained to gain analytical insights. Numerical results validate the correctness of analysis, and present insights on optimal solutions. Finally, we present insights on global-optimal PA by which fairness is ensured and gains of about 55.12%, 69.30%, and 19.11%, respectively are achieved, compared to fixed PA and individual users' optimal PAs

Decoding Orders and Power Allocation for Untrusted NOMA: A Secrecy Perspective

The amalgamation of non-orthogonal multiple access (NOMA) and physical layer security is a significant research interest for providing spectrally-efficient secure fifth-generation networks. Observing the secrecy issue among multiplexed NOMA users, which is stemmed from successive interference cancellation based decoding at receivers, we focus on safeguarding untrusted NOMA. Considering the problem of each user's privacy from each other, the appropriate secure decoding order and power allocation (PA) for users are investigated. Specifically, a decoding order strategy is proposed which is efficient in providing positive secrecy at all NOMA users. An algorithm is also provided through which all the feasible secure decoding orders in accordance with the proposed decoding order strategy can be obtained. Further, in order to maximize the sum secrecy rate of the system, the joint solution of decoding order and PA is obtained numerically. Also, a sub-optimal decoding order solution is proposed. Lastly, numerical results present useful insights on the impact of key system parameters and demonstrate that average secrecy rate performance gain of about 27 dB is obtained by the jointly optimized solution over different relevant schemes

Untrusted NOMA with Imperfect SIC: Outage Performance Analysis and Optimization

Non-orthogonal multiple access (NOMA) has come to the fore as a spectral-efficient technique for fifth-generation and beyond communication networks. We consider the downlink of a NOMA system with untrusted users. In order to consider a more realistic scenario, imperfect successive interference cancellation is assumed at the receivers during the decoding process. Since pair outage probability (POP) ensures a minimum rate guarantee to each user, it behaves as a measure of the quality of service for the pair of users. With the objective of designing a reliable communication protocol, we derive the closed-form expression of POP. Further, we find the optimal power allocation that minimizes the POP. Lastly, numerical results have been presented which validate the exactness of the analysis, and reveal the effect of various key parameters on achieved pair outage performance. In addition, we benchmark optimal power allocation against equal and fixed power allocations with respect to POP. The results indicate that optimal power allocation results in improved communication reliability

Explaining risk for suicidal ideation in adolescent offspring of mothers with depression

Background. It is well-established that offspring of depressed mothers are at increased risk for suicidal ideation. However, pathways involved in the transmission of risk for suicidal ideation from depressed mothers to offspring are poorly understood. The aim of this study was to examine the contribution of potential mediators of this association, in-cluding maternal suicide attempt, offspring psychiatric disorder and the parent–child relationship. Method. Data were utilized from a population-based birth cohort (ALSPAC). Three distinct classes of maternal depres-sion symptoms across the first 11 years of the child’s life had already been identified (minimal, moderate, chronic-severe). Offspring suicidal ideation was assessed at age 16 years. Data were analysed using structural equation modelling. Results. There was evidence for increased risk of suicidal ideation in offspring of mothers with chronic-severe depression symptoms compared to offspring of mothers with minimal symptoms (odds ratio 3.04, 95 % confidence interval 2.19– 4.21). The majority of this association was explained through maternal suicide attempt and offspring psychiatric dis-order. There was also evidence for an independent indirect effect via the parent–child relationship in middle childhood. There was no longer evidence of a direct effect of maternal depression on offspring suicidal ideation after accounting for all three mediators. The pattern of results was similar when examining mechanisms for maternal moderate depression symptoms. Conclusions. Findings highlight that suicide prevention efforts in offspring of depressed mothers should be particularly targeted at both offspring with a psychiatric disorder and offspring whose mothers have made a suicide attempt. Interventions aimed at improving the parent–child relationship may also be beneficial

Exploring symbolic violence in the everyday : misrecognition, condescension, consent and complicity

The empirical material for the article was collected during a project funded by FAS (now FORTE), the Swedish Research Council for Health, Working Life and Welfare.In this paper, we draw on Pierre Bourdieu's concepts of 'misrecognition', 'condescension' and 'consent and complicity' to demonstrate how domination and violence are reproduced in everyday interactions, social practices, institutional processes and dispositions. Importantly, this constitutes symbolic violence, which removes the victim's agency and voice. Indeed, we argue that as symbolic violence is impervious, insidious and invisible, it also simultaneously legitimises and sustains other forms of violence as well. Understanding symbolic violence together with traditional discourses of violence is important because it provides a richer insight into the 'workings' of violence, and provides new ways of conceptualising violence across a number of social fields and new strategies for intervention. Symbolic violence is a valuable tool for understanding contentious debates on the disclosure of violence, women leaving or staying in abusive relationships or returning to their abusers. While we focus only on violence against women, we recognise that the gendered nature of violence produces its own sets of vulnerabilities against men and marginalised groups, such as LGBT. The paper draws on empirical research conducted in Sweden in 2003. Sweden is an interesting case study because despite its progressive gender equality policies, there has been no marked decrease in violence towards women by men.PostprintPeer reviewe

Synchronous imaging of coherent plasma fluctuations

A new method for imaging high frequency plasma fluctuations is described. A phase locked loop and field programmable gate array are used to generate gating triggers for an intensified CCD camera. A reference signal from another diagnostic such as a magnetic probe ensures that the triggers are synchronous with the fluctuation being imaged. The synchronous imaging technique allows effective frame rates exceeding millions per second, good signal to noise through the accumulation of multiple exposures per frame, and produces high resolution images without generating excessive quantities of data. The technique can be used to image modes in the MHz range opening up the possibility of spectrally filtered high resolution imaging of MHD instabilities that produce sufficient light fluctuations. Some examples of projection images of plasma fluctuations on the H-1NF heliac obtained using this approach are presented here.This work was supported by the Education Investment Fund under the Super Science Initiative of the Australian Government. S.R.H. wishes to thank AINSE Ltd. for providing financial assistance to enable this work on H-1NF to be conducted. J.H. and B.B. acknowledge support from the Australian Research Council Discovery, Grant Nos. DP110104833 and DP0666440, respectively

Examining Temporal Variation of the Fermi Coupling Constant using SNe Ia Light Curves

In standard model, the Fermi coupling constant, $G_F$, sets the strength of electroweak decay. We attempt an approach to constrain the temporal variation of the Fermi coupling constant $G_F$. To probe it, Type Ia supernovae (SNe Ia) light curves are being used as a source of reliable primordial nucleosynthesis events across the redshifts. We utilized studies suggesting that in the initial phase after the SNe Ia explosion, the electroweak decay of $^{56}Ni \rightarrow ^{56}Co \rightarrow ^{56}Fe$ is the key contributor to powering the SNe Ia light curve. We hence used the Pan-STARRS supernovae catalog having 1169 supernovae light curves in $g$, $r$, $i$, and $z$ spectral filters. The post-peak decrease in the apparent magnitude of light curves (in the rest frame of SNe) was related to the electroweak decay rate of primordial nucleosynthesis. Further, the decay rate relates to $G_F$. To keep the analysis independent of the cosmological model, we used the Hubble parameter measurement and a non-parametric statistical method, the Gaussian Process. Our study suggests a small yet finite temporal variation of $G_F$ and puts a strong upper bound on the present value of the fractional change in the Fermi coupling constant i.e; $\dfrac{\dot G_F}{G_F}\big\rvert_{z=0} \approx 10^{-11} yr^{-1}$ using datasets spread over a redshift range $0<z<0.75$.Comment: 14 pages, 7 figures, 1 tabl