Salicylaldehyde and dihydroisobenzofuran derivatives from the marine fungus <i>Zopfiella marina</i>

<p>Two salicylaldehyde derivatives (<b>1</b> and <b>2</b>), a hydroxymethylphenol (<b>3</b>), five dihydroisobenzofuran (<b>4</b>–<b>8</b>) derivatives, and a 5-chloro-3-deoxyisoochracinic acid (<b>9</b>), together with a known 3-deoxyisoochracinic acid (<b>10</b>) were isolated from the marine fungus <i>Zopfiella marina</i> BCC 18240 (or NBRC 30420). The structures of these compounds were elucidated by extensive spectroscopic analysis. Compound <b>1</b> showed weak antituberculous activity against <i>Mycobacterium tuberculosis</i> H37Ra, and antibacterial activity against <i>Bacillus cereus</i> with MIC values of 25 and 12.5 μg/mL, respectively.</p