5 research outputs found

    Regression analyses of radiotracer accumulation levels and intraplaque macrophage infiltration/number of apoptotic cells.

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    <p>Positive correlations were observed between the <sup>14</sup>C-FDG accumulation level and macrophage infiltration (Mac-2-positive areas) (<b>A</b>), and between the <sup>99m</sup>Tc-annexin A5 accumulation level and apoptotic cell number (TUNEL-positive cells) (<b>B</b>).</p

    Irbesartan Decreases <sup>14</sup>C-FDG and <sup>99m</sup>Tc-annexin A5 Accumulation Levels.

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    <p>The autoradiogram produced by <sup>14</sup>C signal (<b>A, B</b>) showed a significant decrease in <sup>14</sup>C-FDG uptake levels; and the autoradiogram produced by <sup>99m</sup>Tc signal (<b>C, D</b>) showed a significant decrease in <sup>99m</sup>Tc-annexin A5 accumulation level in the irbesartan-treated mice. <i>M</i> = myocardium; <i>I</i> = intima; <i>L</i> = lumen.</p

    Irbesartan Attenuates Lesion Formation and Lipid Deposition.

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    <p>Movat's pentachrome staining (<b>A, B</b>) showed a significant decrease in intimal areas; and Oil Red O staining (<b>C, D</b>) showed a significant decrease in lipid deposition area in the irbesartan-treated mice. <i>M</i> = myocardium; <i>I</i> = intima; <i>L</i> = lumen.</p

    Irbeartan Suppresses MCP-1 mRNA Expression in THP-1 Monocytes and Activates PPARγ in Reporter Cells.

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    <p>Irbesartan significantly suppressed the MCP-1 mRNA expression in THP-1 cells treated with TNF-α (A). Irbesartan significantly activated PPARγ at 3 µM and further activation was observed at higher concentrations, whereas valsartan at its highest concentration (81 µM) only slightly activated PPARγ. Values are means±SD of three separate experiments. *<i>P</i><0.05 vs valsartan-treated cells; <sup>†</sup><i>P</i><0.05 vs ARB untreated cells.</p

    Additional file 1: of The location of the bladder neck in postoperative cystography predicts continence convalescence after radical prostatectomy

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    Table S1. Perioperative characteristics of the continent and incontinent patients at 1 month. Table S2. Perioperative characteristics of the continent and incontinent patients at 3 months. Table S3. Perioperative characteristics of the continent and incontinent patients at 6 months. Table S4. Perioperative characteristics of the continent and incontinent patients at 12 months. Table S5.Comparison of perioperative clinical factors between the low- and high-BNPS ratio groups. (PPTX 51 kb
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