Nonlinear simulation of resistive ballooning modes in the Large Helical Device

Nonlinear simulations of a magnetohydrodynamic (MHD) plasma in full three-dimensional geometry of the Large Helical Device (LHD) [O. Motojima et al., Phys. Plasmas 6, 1843 (1999)] are conducted. A series of simulations shows growth of resistive ballooning instability, for which the growth rate is seen to be proportional to the one-third power of the resistivity. Nonlinear saturation of the excited mode and its slow decay are observed. Distinct ridge/valley structures in the pressure are formed in the course of the nonlinear evolution. The compressibility and the viscous heating, as well as the thermal conduction, are shown to be crucial to suppress the pressure deformations. Indication of a pressure-driven relaxation phenomenon that leads to an equilibrium with broader pressure profile is observed

Dynamics of spherical tokamak plasma on the internal reconnection event

Nonlinear magnetohydrodynamic (MHD) simulations are executed to investigate the dynamical behavior of the relaxation phenomenon observed in spherical tokamak (ST) plasma that is known as the Internal Reconnection Event (IRE). The simulation results successfully reproduce several key features of IRE, and the physical mechanisms are revealed. A sudden collapse of the pressure profile takes place as a result of a nonlinear time development of a pressure-driven instability. A magnetic reconnection induced between the internal and the external magnetic field is found to play a crucial role in determining the nature of the overall process, namely, the rapid expulsion of the plasma heat energy due to the pressure imbalance along the reconnected field lines, and the large distortion in the overall shape. The resultant deformations in overall shape of the plasma are in good agreement with the experimental observations

Sabellaria tottoriensis n. sp. (Annelida: Polychaeta: Sabellariidae) from Shallow Water off Tottori, the Sea of Japan

A new species of the genus Sabellaria Lamarck, 1812 (Annelida: Polychaeta: Sabellariidae), is described from shallow water off Tottori, the Sea of Japan. Sabellaria tottoriensis n. sp., is gregarious with tubes constructed of sand and shell debris. The new species is distinguished by the character combination of 1 or 2 pairs of nuchal spines, two forms (long and short) of opercular paleae in the middle row, with the slender blades of long ones recurved outward. Detailed morphological features of the species are described and compared with other Japanese and worldwide congeners

Burst synchronization in two pulse-coupled resonate-and-fire neuron circuits

The present paper addresses burst synchronization in out of phase observed in two pulse-coupled resonate-and-fire neuron (RFN) circuits. The RFN circuit is a silicon spiking neuron that has second-order membrane dynamics and exhibits fast subthreshold oscillation of membrane potential. Due to such dynamics, the behavior of the RFN circuit is sensitive to the timing of stimuli. We investigated the effects of the sensitivity and the mutual interaction on the dynamic behavior of two pulse-coupled RFN circuits, and will demonstrate out of phase burst synchronization and bifurcation phenomena through circuit simulations.Applications in Artificial Intelligence - ApplicationsRed de Universidades con Carreras en Informática (RedUNCI

Simultaneous Polymerization by Cationic and Anionic Catalysts

In our previous paper simultaneous cationic and anionic polymerizations have been reported to proceed in the case of the graft copolymerization of β-propiolactone with Nvinyl carbazole onto the trunk polymers containing -SO₃ Na or -COOH groups. In this paper, the simultaneous polymerization by cationic and anionic catalysts was carried out in a liquid system for homopolymerization. The cationic and anionic polymerizations were recognized to occur simultaneously at the comparative rates of both cationic and anionic polymerizations, at least in the case having one of the following conditions at ; (i) relatively heterogeneous system. (ii) the reaction medium having high dielectric constant, or (iii) relatively stable growing anionic and cationic ends

Assessing the internal structure of landslide dams subject to possible piping erosion by means of microtremor chain array and self-potential surveys

An integrated geophysical approach comprising microtremor chain array and self-potential surveys was used to assess the internal structure of landslide dams subject to possible piping erosion in selected sites in Japan and Kyrgyzstan. The non-invasive geophysical approach is cost effective, environmentally friendly and portable, and hence, it has proven to be valuable for the geotechnical assessment of landslide dams where piping can trigger failure of the dam. While the microtremor chain array survey results revealed the internal structure of the landslide dam, the self-potential survey results indicated the path of anomalous seepage zones. In the surveyed sites of long-existing landslide dams, the presence of a seepage path in the dam was confirmed by a good correlation between the areas of low phase velocity and large negative self-potential anomalies. In summary, this integrated geophysical approach could be useful for the early risk assessment of landslide dams and prediction of landslide dam failure by piping

Regulation of Oxidative Stress and Cardioprotection in Diabetes Mellitus

Analysis of the Framingham data has shown that the risk of heart failure is increased substantially among diabetic patients, while persons with the metabolic syndrome have an increased risk of both atherosclerosis and diabetes mellitus. Sleep apnea may be related to the metabolic syndrome and systemic inflammation through hypoxia, which might also cause the cardiac remodeling by increased oxidative stress. On the other hand, the renin-angiotensin system is activated in diabetes, and local angiotensin II production may lead to oxidative damage via the angiotensin II type 1 receptor. Basic and clinical data indicate that angiotensin II receptor blockers have the potential to preserve left ventricular function and prevent cardiac remodeling that is exaggerated by oxidative stress in patients with diabetes. Thus, alleviation of oxidative stress might be one possible strategy in the treatment of diabetic patients associated with sleep apnea

Altered autonomic nervous system activity as a potential etiological factor of premenstrual syndrome and premenstrual dysphoric disorder

<p>Abstract</p> <p>Background</p> <p>Premenstrual syndrome (PMS) encompasses a wide variety of cyclic and recurrent physical, emotional, and behavioral symptoms occurring during the late luteal phase of the menstrual cycle and abating shortly following the beginning of menses. Although PMS is widely recognized, its etiopathogenesis is not yet understood. The present study investigates whether the activity of the autonomic nervous system, which plays a vital role in orchestrating physiological homeostasis within the human body, is altered during the menstrual cycle of women with different degrees of premenstrual symptomatology.</p> <p>Methods</p> <p>Sixty-two women in their 20s to 40s with regular menstrual cycles participated in this study. All subjects were examined during the follicular and late luteal phases. Cycle phase was determined by the onset of menstruation and oral temperature and was verified by concentrations of ovarian hormones, estrone, and pregnanediol in a urine sample taken early in the morning. Autonomic nervous system activity was assessed by means of heart-rate variability (HRV) power spectral analysis during supine rest. The Menstrual Distress Questionnaire was used to evaluate physical, emotional, and behavioral symptoms accompanying the menstrual cycle of the subjects. The subjects were categorized in three groups, Control, PMS, and premenstrual dysphoric disorder (PMDD) groups, depending on the severity of premenstrual symptomatology.</p> <p>Results</p> <p>No intramenstrual cycle difference in any of the parameters of HRV was found in the Control group, which had no or a small increase in premenstrual symptoms. In contrast, Total power and high frequency power, which reflect overall autonomic and parasympathetic nerve activity, respectively, significantly decreased in the late luteal phase from the follicular phase in the PMS group. As for the PMDD group, which had more severe symptoms premenstrually, heart-rate fluctuation as well as all components of the power spectrum of HRV were markedly decreased regardless of the menstrual cycle compared to those of the other two groups.</p> <p>Conclusion</p> <p>Several theories have been proposed to explain the underlying mechanisms of PMS with its complex web of bio-psycho-social factors. Although causes and consequences continue to elude, the present study provides intriguing and novel findings that the altered functioning of the autonomic nervous system in the late luteal phase could be associated with diverse psychosomatic and behavioral symptoms appearing premenstrually. In addition, when symptoms become more severe (as seen in women with PMDD), the sympathovagal function might be more depressed regardless of the menstrual cycle.</p

Leisure-time, occupational, and commuting physical activity and risk of type 2 diabetes in Japanese workers: a cohort study

Table S1. Association between moderate-intensity and vigorous-intensity exercise during leisure and risk of type 2 diabetes. Table S2. Risk of type 2 diabetes associated with specific type of leisure-time exercise. (DOCX 47 kb

Platelet-rich plasma does not reduce skeletal muscle fibrosis after distraction osteogenesis

Background: Skeletal muscle fibrosis caused by an increase in collagen deposition often occurs after distraction osteogenesis. Although studies are available reporting the effects of platelet-rich plasma (PRP) on tissue healing following injury, current findings remain controversial. This study focused on determining whether PRP reduces skeletal muscle fibrosis caused by distraction osteogenesis. Methods: Tibial osteotomies were performed on 8-week-old wild type mice, and tibiae were distracted at a rate of 0.42 mm/day for 2 weeks, starting 1 week after osteotomy. Immediately after distraction was completed (3 weeks after osteotomy), PRP or phosphate buffered saline (as a sham) was injected into the gastrocnemius (GC) muscle. The GC muscles were harvested and analyzed. Results: The amount and area of collagenous tissue increased in both the PRP and control groups following distraction osteogenesis, but the changes were not significantly different between both groups at all time points (p = 0.89, 0.45, 0.33 and 0.52 at 4, 6, 8 and 10 weeks). Conclusion: From this study, our results suggest that PRP did not significantly reduce skeletal muscle fibrosis due to distraction osteogenesis