405 research outputs found
<Abstract of Published Report>Association of Extracellular-Superoxide Dismutase Phenotype with the Endothelial Constitutive Nitric Oxide Synthase Polymorphism.
<Abstract of annual report>Interactions between Human Extracellular Superoxide Dismutase C and Sulfated Polysaccharides.
Association of extracellular-superoxide dismutase phenotype with the endothelial constitutive nitric oxide synthase polymorphism
AbstractThe distribution of extracellular-superoxide dismutase (EC-SOD) levels in healthy Australian subjects was consistent with two distinct phenotypes in which the smaller group of subjects (3.3%) had 15-fold higher levels. The EC-SOD levels in individuals homozygous for endothelial constitutive nitric oxide synthase 4a (ecNOS4a), a rare allele for ecNOS repeat polymorphism at intron 4, were significantly lower than those in ecNOS4A/a and ecNOS4A/A subjects. Furthermore, NO levels were negatively correlated with the EC-SOD levels in common EC-SOD phenotype subjects. Whilst the mechanism remains speculative, it is possible that there is a significant interaction between EC-SOD and ecNOS, or that common factor(s), either genetic or environmental, influence both of them
<Abstract of Published Report>Nitric oxide and its decomposed derivatives decrease the binding of extracellular-superoxide dismutase to the endothelial cell surface.
<Abstract of Published Report>Inhibitory Effect of Nitric Oxide on the Induction of Cytochrome P450 3A4 mRNA by 1,25-Dihydroxyvitamin D_3in Caco-2 cells.
<Abstract of Published Report>The Students\u27 Awareness about Practical Training in a Hospital Pharmacy.
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