Multiple linear regression analysis of epicardial fat area (EFA) and adipokines.

<p>Multiple linear regression analysis of epicardial fat area (EFA) and adipokines.</p

Patient characteristics.

<p>Patient characteristics.</p

Correlations between serum irisin and adipokines (adiponectin, leptin) level and the findings of BIA method or CT scan.

<p>A-C: Relationships between body fat mass and serum irisin and adipokines level (leptin (A), adiponectin (B), and irisin (C)). D-F: Relationships between epicardial fat area (EFA) and serum irisin and adipokines level (leptin (D), adiponectin (E), and irisin (F)).</p

Correlation matrix between fat volume and biochemical data.

<p>Correlation matrix between fat volume and biochemical data.</p

Correlation matrix between clinical data and serum irisin and adipokines (adiponectin and leptin) concentration.

<p>Correlation matrix between clinical data and serum irisin and adipokines (adiponectin and leptin) concentration.</p

Sex differences of various parameters.

<p>Sex differences of various parameters.</p

Measurement of fat area by CT scan.

<p>A: Measurement of epicardial fat area (EFA). Two representative cases are shown. The image is shown at the position where the heart becomes a long axis image with respect to the apex of the heart in the axial section image with ROI. The heart surrounded by ROI and the epicardial fat area (EFA, cm²) was measured by a semi-automated method with CT value defined as -150 to -50 HU. Fat is identified as brown color. EFA is estimated as 4.14 cm² and 22.9 cm², respectively. B: Measurement of subcutaneous and visceral fat area. The areas of abdominal visceral fat (VFA, cm², brown color), and subcutaneous fat (SFA, cm², blue color) were determined at the cross-sectional image of the umbilicus. Fat was measured by a semi-automated method with CT value defined as -150 to -50 HU.</p

Relationships between various serum adipokine level.

<p>Relationships between various serum adipokine level.</p

Correlations between serum irisin and adipokines (adiponectin, leptin) concentration and clinical data.

<p>A-C: Relationship between age and serum irisin and adipokines level (irisin (A), adiponectin (B), leptin (C)). D-F: Relationship between BMI and serum adipokines level (irisin (D), adiponectin (E), leptin (F)).</p

Correlations between epicardial fat area (EFA) and clinical data.

<p>Relationship between epicardial fat area (EFA) and BMI (A), triglyceride (TG, B), HbA1C (C), HOMA-IR (D), body fat mass (E), and body fat percentage (F).</p