95 research outputs found

    Authentic Leadership: A Historical Perspective

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    The purpose of this paper is to interpret the historical meanings conveyed by Barnard's classic works and use them for theorizing about authenticity of leaders in executive roles. Our analysis employs an interpretative logic for meanings of historical ideas proposed by Bevir. As an outcome of this analysis, we identify the conditions that contribute to the failure, crisis, tragedy, and/or success of leader authenticity. In addition, we discuss practical and research implications of the proposed framework.Yeshttps://us.sagepub.com/en-us/nam/manuscript-submission-guideline

    Systems genetics identifies a role for Cacna2d1 regulation in elevated intraocular pressure and glaucoma susceptibility

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    Glaucoma is a multi-factorial blinding disease in which genetic factors play an important role. Elevated intraocular pressure is a highly heritable risk factor for primary open angle glaucoma and currently the only target for glaucoma therapy. Our study helps to better understand underlying genetic and molecular mechanisms that regulate intraocular pressure, and identifies a new candidate gene, Cacna2d1, that modulates intraocular pressure and a promising therapeutic, pregabalin, which binds to CACNA2D1 protein and lowers intraocular pressure significantly. Because our study utilizes a genetically diverse population of mice with kno

    The effect of friction stir processing on the microstructure and mechanical properties of an aluminum lithium alloy

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    The article of record as published may be found at http://dx.doi.org/10.1007/s11661-008-9698-8Friction stir processing (FSP) was conducted on a wrought plate of AA2099 to refine and homogenize the microstructure and enhance the through-thickness ductility and fracture resistance. Optical microscopy (OM), orientation imaging microscopy (OIM), and transmission electron microscopy (TEM) methods were employed to evaluate microstructure and micro- texture in as-received material and in material subjected to FSP as well as postprocessing heat treatments. Hardness and orientation-dependent tensile test data were combined with anticlastic bending fatigue data to characterize the as-received, processed, and processed and heat-treated conditions of the material.Defense Advanced Research Projects Agency (DARPA)Office of Naval Research (ONR)Contract no. N00014-06-WR-2-0196 (ONR
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