7 research outputs found
<sup>1</sup>H MAS NMR Study of Cysteine-Coated Gold Nanoparticles
<sup>1</sup>H MAS NMR experiments were performed on gold
nanoparticles
coated with l-cysteine. The experiments show that l-cysteine molecules are zwitterions and support a structural model
of cysteine forming two layers. The inner layer is composed of cysteine
molecules chemisorbed to the gold surface via the sulfur atom. The
outer layer interacts with the chemisorbed layer. The <sup>1</sup>H NMR suggests that the cysteine in the outer layer exhibits large
amplitude motion about specific carbon–carbon bonds
<sup>1</sup>H MAS NMR Study of Cysteine-Coated Gold Nanoparticles
<sup>1</sup>H MAS NMR experiments were performed on gold
nanoparticles
coated with l-cysteine. The experiments show that l-cysteine molecules are zwitterions and support a structural model
of cysteine forming two layers. The inner layer is composed of cysteine
molecules chemisorbed to the gold surface via the sulfur atom. The
outer layer interacts with the chemisorbed layer. The <sup>1</sup>H NMR suggests that the cysteine in the outer layer exhibits large
amplitude motion about specific carbon–carbon bonds
<sup>1</sup>H MAS NMR Study of Cysteine-Coated Gold Nanoparticles
<sup>1</sup>H MAS NMR experiments were performed on gold
nanoparticles
coated with l-cysteine. The experiments show that l-cysteine molecules are zwitterions and support a structural model
of cysteine forming two layers. The inner layer is composed of cysteine
molecules chemisorbed to the gold surface via the sulfur atom. The
outer layer interacts with the chemisorbed layer. The <sup>1</sup>H NMR suggests that the cysteine in the outer layer exhibits large
amplitude motion about specific carbon–carbon bonds
l‑Cysteine Interaction with Au<sub>55</sub> Nanoparticle
Simulations of l-cysteine molecules attaching
on Au nanoparticles provide insight on how larger biomolecules (such
as proteins and peptides) can interact with Au nanoparticles. The
attaching mode is still in debate and of strong impact on the fundamental
research in biosensors and biomedicine. We used a density functional
theory (DFT) approach to calculate the interactions between l-cysteine molecules and the quantum sized Au nanoparticle Au<sub>55</sub>. Our results support the attaching mode recognized in solid-state
NMR studies, which indicate that a double layer of l-cysteine
molecules is the likely configuration. A strong electronic interaction
between gold and sulfur atoms establishes a strong-bonding inner layer,
while a hydrogen-bond network between zwitterion-structured cysteine
molecules stabilizes the existence of a second layer with thiol (−SH)
groups oriented outward. Such a structure has high potential for further
biofunctionalization
Boyce et al. 2018 Tables S1-S17.xlsx
Supplemental tables for "Discovery of psychoactive plant and mushroom alkaloids in ancient fungal cicada pathogens.
Boyce et al. Movie S2
<p><b>Movie
S2.</b>
Living Brood V <i>Magicicada septendecim</i>
with conidial spore infection.</p
Boyce et al. 2018 Movie S1
<p><b>Movie
S1.</b>
Living <i>Platypedia putnami</i> with
conidial and resting spore infections.</p