7 research outputs found

    <sup>1</sup>H MAS NMR Study of Cysteine-Coated Gold Nanoparticles

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    <sup>1</sup>H MAS NMR experiments were performed on gold nanoparticles coated with l-cysteine. The experiments show that l-cysteine molecules are zwitterions and support a structural model of cysteine forming two layers. The inner layer is composed of cysteine molecules chemisorbed to the gold surface via the sulfur atom. The outer layer interacts with the chemisorbed layer. The <sup>1</sup>H NMR suggests that the cysteine in the outer layer exhibits large amplitude motion about specific carbon–carbon bonds

    <sup>1</sup>H MAS NMR Study of Cysteine-Coated Gold Nanoparticles

    No full text
    <sup>1</sup>H MAS NMR experiments were performed on gold nanoparticles coated with l-cysteine. The experiments show that l-cysteine molecules are zwitterions and support a structural model of cysteine forming two layers. The inner layer is composed of cysteine molecules chemisorbed to the gold surface via the sulfur atom. The outer layer interacts with the chemisorbed layer. The <sup>1</sup>H NMR suggests that the cysteine in the outer layer exhibits large amplitude motion about specific carbon–carbon bonds

    <sup>1</sup>H MAS NMR Study of Cysteine-Coated Gold Nanoparticles

    No full text
    <sup>1</sup>H MAS NMR experiments were performed on gold nanoparticles coated with l-cysteine. The experiments show that l-cysteine molecules are zwitterions and support a structural model of cysteine forming two layers. The inner layer is composed of cysteine molecules chemisorbed to the gold surface via the sulfur atom. The outer layer interacts with the chemisorbed layer. The <sup>1</sup>H NMR suggests that the cysteine in the outer layer exhibits large amplitude motion about specific carbon–carbon bonds

    l‑Cysteine Interaction with Au<sub>55</sub> Nanoparticle

    No full text
    Simulations of l-cysteine molecules attaching on Au nanoparticles provide insight on how larger biomolecules (such as proteins and peptides) can interact with Au nanoparticles. The attaching mode is still in debate and of strong impact on the fundamental research in biosensors and biomedicine. We used a density functional theory (DFT) approach to calculate the interactions between l-cysteine molecules and the quantum sized Au nanoparticle Au<sub>55</sub>. Our results support the attaching mode recognized in solid-state NMR studies, which indicate that a double layer of l-cysteine molecules is the likely configuration. A strong electronic interaction between gold and sulfur atoms establishes a strong-bonding inner layer, while a hydrogen-bond network between zwitterion-structured cysteine molecules stabilizes the existence of a second layer with thiol (−SH) groups oriented outward. Such a structure has high potential for further biofunctionalization
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