Community Radio Broadcasting and Positioning

Community radio in Australia comprises 340 independent not-for-profit organisations filling niche market segments. However, they often strongly compete with high profile mainstream commercial sophisticated broadcasting companies. For community radio to successfully compete means developing a clear market position to assist their program development, management system and promotion format. This paper explores the status of community radio organisations in Australia and examines the market research process adopted by one organisation to test and validate its market position. Both listeners and non-listeners of the station were sampled. Analysis indicated that for the community radio broadcaster they were well positioned by the cognitive understanding of their constituent members. This paper presents, tests and affirms the market position held by the organisation and the results provide affirmation to the programming content and broadcast structure. In addition it assists in filling a research gap as it relates to positioning and community radio organisations.Griffith Business School, Department of MarketingFull Tex

Marketing of Higher Education: Australia's New Export Phenomenon

Griffith Business School, Department of MarketingNo Full Tex

Functional Significance of the Interaction between the mRNA-binding Protein, Nab2, and the Nuclear Pore-associated Protein, Mlp1, in mRNA Export*S⃞

Nuclear export of mRNA requires several key mRNA-binding proteins that recognize and remodel the mRNA and target it for export via interactions with the nuclear pore complex. In Saccharomyces cerevisiae, the shuttling heterogeneous nuclear ribonucleoprotein, Nab2, which is essential for mRNA export, specifically recognizes poly(A) RNA and binds to the nuclear pore-associated protein, myosin-like protein 1 (Mlp1), which functions in mRNA export and quality control. Specifically, the N-terminal domain of Nab2 (Nab2-N; residues 1–97) interacts directly with the C-terminal globular domain of Mlp1 (CT-Mlp1: residues 1490–1875). Recent structural and binding studies focused on Nab2-N have shown that Nab2-N contains a hydrophobic patch centered on Phe73 that is critical for interaction with Mlp1. Engineered amino acid changes within this patch disrupt the Nab2/Mlp1 interaction in vitro. Given the importance of Nab2 and Mlp1 to mRNA export, we have examined the Nab2/Mlp1 interaction in greater detail and analyzed the functional consequences of disrupting the interaction in vivo. We find that the Nab2-binding domain of Mlp1 (Mlp1-NBD) maps to a 183-residue region (residues 1586–1768) within CT-Mlp1, binds directly to Nab2 with micromolar affinity, and confers nuclear accumulation of poly(A) RNA. Furthermore, we show that cells expressing a Nab2 F73D mutant that cannot interact with Mlp1 exhibit nuclear accumulation of poly(A) RNA and that this nab2 F73D mutant genetically interacts with alleles of two essential mRNA export genes, MEX67 and YRA1. These data provide in vivo evidence for a model of mRNA export in which Nab2 is important for targeting mRNAs to the nuclear pore for export