Operations and Maintenance of Unspared Compressor Trains and their Auxiliary Systems

TutorialThis tutorial provides general guidance on the topic of operations and maintenance of unspared compressor trains and their auxiliary systems. It is targeted towards entry level engineers working in the operations and maintenance field. The tutorial will be divided into two major sections. The first section covers ‘online’ checks and inspections including vibration monitoring, auxiliary system monitoring, regular visual inspections, online preventative maintenance, documentation maintenance, and performance monitoring. The second section covers the efforts associated with turn-around and maintenance (planned or un-planned). This includes details on maintenance intervals, preparation and planning for outages and peripheral system checks during an outage

US Cosmic Visions: New Ideas in Dark Matter 2017: Community Report

This white paper summarizes the workshop "U.S. Cosmic Visions: New Ideas in Dark Matter" held at University of Maryland on March 23-25, 2017.Comment: 102 pages + reference

Characterizing smoking-induced transcriptional heterogeneity in the human bronchial epithelium at single-cell resolution

The human bronchial epithelium is composed of multiple distinct cell types that cooperate to defend against environmental insults. While studies have shown that smoking alters bronchial epithelial function and morphology, its precise effects on specific cell types and overall tissue composition are unclear. We used single-cell RNA sequencing to profile bronchial epithelial cells from six never and six current smokers. Unsupervised analyses led to the characterization of a set of toxin metabolism genes that localized to smoker ciliated cells, tissue remodeling associated with a loss of club cells and extensive goblet cell hyperplasia, and a previously unidentified peri-goblet epithelial subpopulation in smokers who expressed a marker of bronchial premalignant lesions. Our data demonstrate that smoke exposure drives a complex landscape of cellular alterations that may prime the human bronchial epithelium for disease