Scheme depicting the most salient features of dysphonia in HD and their relationship to motor symptoms.

<p>Scheme depicting the most salient features of dysphonia in HD and their relationship to motor symptoms.</p

Selected pairs of the phonatory measures with classification boundary separating HD and HC subjects.

<p>Selected pairs of the phonatory measures with classification boundary separating HD and HC subjects.</p

Overview of the phonatory measurements applied to sustained vowel phonations.

<p>Overview of the phonatory measurements applied to sustained vowel phonations.</p

Results of voice analyses in HD and HC subjects.

*<p><i>p</i><0.05;</p>**<p><i>p</i><0.01;</p>***<p><i>p</i><0.001.</p><p>MPT = maximum phonation time, MPT_VB = maximum phonation time until first break, NVB = number of voice breaks, DUV = degree of voicelessness, F0 SD = variability of fundamental frequency, RPDE = recurrence period density entropy, PPE = pitch period entropy, HNR = harmonics-to-noise ratio, DFA = detrended fluctuation analysis, MFCC = mel-frequency cepstral coefficient.</p