Role-play and Use Case Cards for Requirements Review

This paper presents a technique that uses role-play and index cards to review use cases and to assist in making use case development more accessible and better guided. The technique is based on the established CRC card technique used for object-oriented design. In our technique, essential use cases are recorded on index cards, and role-play is used for development and review. The paper presents the technique, and outlines our experience in applying it

Counting Protocols for Reliable End-to-End Transmission

AbstractWe present and analyze the performance of two newcounting protocols. Counting protocols use bounded headers yet provide a reliable FIFO channel in a computer network in which packets may be lost or delivered out of order. Using the classic alternating bit protocol as a basis, we derive two counting protocols: (i) theone-bit protocolwhich uses one bit headers and sends one packet per message under ideal conditions, but performs extremely poorly in networks with realistic loss rates and (ii) themode protocolwhich uses multiple-bit headers and whose performance improves as more bits are used in the header

Multiple dispatch in practice

Multiple dispatch uses the run time types of more than one argument to a method call to determine which method body to run. While several languages over the last 20 years have provided multiple dispatch, most object-oriented languages still support only single dispatch — forcing programmers to implement multiple dispatch manually when required. This paper presents an empirical study of the use of multiple dispatch in practice, considering six languages that support multiple dispatch, and also investigating the potential for multiple dispatch in Java programs. We hope that this study will help programmers understand the uses and abuses of multiple dispatch; virtual machine implementors optimise multiple dispatch; and language designers to evaluate the choice of providing multiple dispatch in new programming languages

On the differences between correct student solutions.

ABSTRACT We know that students solve problems in different ways, but we know little about the kinds of variation, or the degree of variation between these student generated solutions. In this paper, we propose a taxonomy that classifies the variation between correct student solutions in objective terms, and we show how the application of the taxonomy provides instructors with additional insight about the differences between student solutions. This taxonomy may be used to inform instructors in selecting examples of code for teaching purposes, and provides the possibility of automatically applying the taxonomy to existing solution sets

Integrated genomic characterization of pancreatic ductal adenocarcinoma

We performed integrated genomic, transcriptomic, and proteomic profiling of 150 pancreatic ductal adenocarcinoma (PDAC) specimens, including samples with characteristic low neoplastic cellularity. Deep whole-exome sequencing revealed recurrent somatic mutations in KRAS, TP53, CDKN2A, SMAD4, RNF43, ARID1A, TGFβR2, GNAS, RREB1, and PBRM1. KRAS wild-type tumors harbored alterations in other oncogenic drivers, including GNAS, BRAF, CTNNB1, and additional RAS pathway genes. A subset of tumors harbored multiple KRAS mutations, with some showing evidence of biallelic mutations. Protein profiling identified a favorable prognosis subset with low epithelial-mesenchymal transition and high MTOR pathway scores. Associations of non-coding RNAs with tumor-specific mRNA subtypes were also identified. Our integrated multi-platform analysis reveals a complex molecular landscape of PDAC and provides a roadmap for precision medicine