Mesenteric Panniculitis in Sjögren’s Syndrome: A New Systemic Manifestation to Consider?

The association between mesenteric panniculitis and Sjögren's syndrome, although rare, is starting to be recognized. Usually, mesenteric panniculitis is symptomatic, presenting with either general or gastrointestinal symptoms. Sjögren's syndrome is an autoimmune disease that typically affects secretory glands, but may have serious systemic involvement. We report the case of a 77-year-old patient in whom accidental discovery of asymptomatic mesenteric panniculitis on computed tomography led to the diagnosis of Sjögren's syndrome with several systemic manifestations

Adenopatia supraclavicular como forma de apresentação de cancro da próstata metastizado

Prostate cancer in its advanced form usually metastasizes to the bone or pelvic ganglia. The involvement of the supraclavicular lymph nodes is rare (0.4% to 1% of all cases)1. Its presentation as a supraclavicular lymphadenopathy is even more unusual with only a few cases described in the literature2-7. In this context, we describe the case of a 62 year old man presenting with a left supraclavicular mass without any other signs or associated symptoms. After all the workup, we established the diagnosis of widely metastasized prostate adenocarcinoma. We bring forward this case as an example of a rare form of presentation of prostate cancer and we use it as a base for discussing an approach to isolated peripheral lymphadenopathy.A neoplasia da próstata na sua forma avançada tem geralmente metastização óssea ou para gânglios pélvicos. O envolvimento de gânglios supraclaviculares é raro (0,4-1% de todos os casos)1 e a sua apresentação como adenopatia supraclavicular é ainda mais rara, com apenas alguns casos descritos na literatura2-7. Neste contexto, apresentamos o caso de um homem de 62 anos, saudável, com tumefação de novo na fossa supraclavicular esquerda, sem sintomas associados. Após a investigação estabeleceu-se o diagnóstico de adenocarcinoma da próstata em fase avançada, com metastização disseminada. Alertamos para uma forma rara de apresentação de adenocarcinoma da próstata e discutimos a abordagem diagnóstica em casos de adenopatias isoladas