Bariatric surgery for prospective living kidney donors with obesity?

Peer Reviewedhttps://deepblue.lib.umich.edu/bitstream/2027.42/151374/1/ajt15260_am.pdfhttps://deepblue.lib.umich.edu/bitstream/2027.42/151374/2/ajt15260.pd

Update on Transanal NOTES for Rectal Cancer: Transitioning to Human Trials

The feasibility of natural orifice translumenal endoscopic surgery (NOTES) resection for rectal cancer has been demonstrated in both survival swine and fresh human cadaveric models. In preparation for transitioning to human application, our group has performed transanal NOTES rectal resection in a large series of human cadavers. This experience both solidified the feasibility of resection and allowed optimization of technique prior to clinical application. Improvement in specimen length and operative time was demonstrated with increased experience and newer platforms. This extensive laboratory experience has paved the way for successful clinical translation resulting in an ongoing clinical trial. To date, based on published reports, 4 human subjects have undergone successful hybrid transanal NOTES resection of rectal cancer. While promising, instrument limitations continue to hinder a pure transanal approach. Careful patient selection and continued development of new endoscopic and flexible-tip instruments are imperative prior to pure NOTES clinical application

Genetic studies for flower yield and component traits in Chrysanthemum morifolium Ramat

Study on genetic variability, character association and path analysis was carried out with sixty chrysan-themum genotypes keeping in mind of their applicability in future crop improvement programmes. High phenotypic and genotypic coefficient of variation were found for the character such as number of flower per plant, number of branches per plant, number of primary branches, number of secondary branches, plant spread and plant height. High heritability coupled with high expected genetic advance was observed for number of flower per plant, number of secondary branches and branches per plant. In general, genotypic correlation coefficients were found to be higher than the phenotypic correlations for most of the characters. Number of flowers per plant showed highly positive significant correlation at both genotypic and phenotypic level with plant spread (0.977,0.974), number of primary branches (0.952,0,828), number of branches per plant (0.956, 0.950), number of flower per spray (0.932, 0.821) and number of secondary branches (0.770, 0.744). Path analysis revealed that plant spread, number of primary branch-es, number of flower per spray and number of branches per plant had highest positive and direct effects on number of flowers per plant at genotypic and phenotypic levels. Thus, the useful cultivars can be used as parents in hybridization programme to obtain admirable progenie

Genetic studies for flower yield and component traits in Chrysanthemum morifolium Ramat

Study on genetic variability, character association and path analysis was carried out with sixty chrysan-themum genotypes keeping in mind of their applicability in future crop improvement programmes. High phenotypic and genotypic coefficient of variation were found for the character such as number of flower per plant, number of branches per plant, number of primary branches, number of secondary branches, plant spread and plant height. High heritability coupled with high expected genetic advance was observed for number of flower per plant, number of secondary branches and branches per plant. In general, genotypic correlation coefficients were found to be higher than the phenotypic correlations for most of the characters. Number of flowers per plant showed highly positive significant correlation at both genotypic and phenotypic level with plant spread (0.977,0.974), number of primary branches (0.952,0,828), number of branches per plant (0.956, 0.950), number of flower per spray (0.932, 0.821) and number of secondary branches (0.770, 0.744). Path analysis revealed that plant spread, number of primary branch-es, number of flower per spray and number of branches per plant had highest positive and direct effects on number of flowers per plant at genotypic and phenotypic levels. Thus, the useful cultivars can be used as parents in hybridization programme to obtain admirable progenie

A strengths-based case management service for people with serious mental illness in Israel: A randomized controlled trial

Case management services for people with serious mental illness are generally found to be effective, but controlled and randomized studies assessing such services are scarce. The aim of the present study was to assess the effectiveness of a new strengths-based case management (SBCM) service in Israel, using a randomized controlled approach. The sample consisted of 1276 individuals with serious mental illness, who consume psychiatric rehabilitation services (PRS) in the community, and were randomly assigned to receive or not to receive the SBCM service in addition to treatment-as-usual PRS. Quality of life, goal setting and attainment, unmet needs, self-efficacy, interpersonal relationships, symptom severity, and service utilization were assessed by clients at onset and after 20 months. Results show that SBCM participants improved in self-efficacy, unmet needs, and general quality of life, and set more goals than the control group. SBCM participants also consumed fewer services at follow-up. Results suggest that SBCM services are effective in helping individuals with serious mental illness set personal goals and use PRS in a better and more focused manner

Current Recommendations on Diagnosis and Management of Right-Sided Diverticulitis

We present the case of a 52-year-old female with recurrent symptomatic ascending colon diverticulitis who ultimately underwent elective laparoscopic right hemicolectomy. The following is a case report and literature review pertaining to right colonic diverticular disease

Intraoperative blood pressure changes as a risk factor for anastomotic leakage in colorectal surgery

Anastomotic leakage is a serious complication after colorectal surgery. Pre- and intraoperative factors may contribute to failure of colorectal anastomosis. In this study we have tried to determine risk factors for anastomotic leakage, with special emphasis on intraoperative blood pressure changes. During a 24-month period, patients receiving a colorectal anastomosis were prospectively evaluated. For each patient preoperative characteristics, intraoperative adverse events and surgical outcome data were collected. Blood pressure changes were calculated as a relative decrease (> 25% and > 40%) from preoperative baseline values. During the study period, 285 patients underwent colorectal surgery with an anastomosis. Fifteen patients developed an anastomotic leakage (5.3%). All patients who developed a leakage had a left-sided procedure (P 40% decrease in diastolic blood pressure (P = 0.049)] were identified as univariate risk factors for anastomotic leakage. The development of an anastomotic leakage after colorectal surgery is related to surgical, patient and anaesthetic risk factors. A high preoperative diastolic blood pressure and profound intraoperative hypotension combined with complex surgery, marked by a blood loss of a parts per thousand yen250 mL and the occurrence of intraoperative adverse events, is associated with an increased risk of developing anastomotic leakag