Resurrecting the exponential and inverse power-law potentials in non-canonical inflation

We study inflation within the framework of non-canonical scalar field. In this scenario, we obtain the inflationary observables such as the scalar spectral index, the tensor-to-scalar ratio, the running of the scalar spectral index as well as the equilateral non-Gaussianity parameter. Then, we apply these results for the exponential and inverse power-law potentials. Our investigation shows that although the predictions of these potentials in the standard canonical inflation are completely ruled out by the Planck 2015 observations, their results in non-canonical scenario can lie inside the allowed regions of the Planck 2015 data. We also find that in non-canonical inflation, the predictions of the aforementioned potentials for the running of the scalar spectral index and the equilateral non-Gaussianity parameter are in well agreement with the Planck 2015 results. Furthermore, we show that in the context of non-canonical inflation, the graceful exit problem of the exponential and inverse power-law potentials is resolved.Comment: 18 pages, 3 figure

Clique polynomials of 22-connected K5K_{5}-free chordal graphs

In this paper, we give a generalization of the author's previous result about real rootedness of clique polynomials of connected $K_{4}$-free chordal graphs to the class of $2$-connected $K_{5}$-free chordal graphs. The main idea is based on the graph-theoretical interpretation of the second derivative of clique polynomials. Finally, we conclude the paper with several interesting open questions and conjectures

Inflation Based on the Tsallis Entropy

We study the inflationary scenario in the Tsallis entropy-based cosmology. The Friedmann equations in this setup can be derived by using the first law of thermodynamics. To derive the relations of the power spectra of the scalar and tensor perturbations in this setup, we reconstruct an $f(R)$ gravity model which is thermodynamically equivalent to our model in the slow-roll approximation. In this way, we find the inflationary observables, including the scalar spectral index and the tensor-to-scalar ratio in our scenario. Then, we investigate two different potentials in our scenario, including the quadratic potential and the potential associated with the natural inflation in which the inflaton is an axion or a pseudo-Nambu-Goldstone boson. We examine their observational viability in light of the Planck 2018 CMB data. We show that although the results of these potentials are in tension with the observations in the standard inflationary setting, their consistency with the observations can be significantly improved within the setup of the Tsallis entropy-based inflation. Moreover, we place constraints on the parameters of the considered inflationary models by using the Planck 2018 data.Comment: 25 pages, 2 figure

Evaluation of the changes in the expression levels of miR-141 and SHP gene in prostate cancer specimens

Introduction: Primary screening tests currently used for prostate cancer (PCa), don’t have sufficient sensitivity and specificity. Therefore, early diagnosis and management of treatment is one of the challenges faced by physicians. Today, more familiar with the signaling pathways involved in the pathogenesis of cancers, several molecules have been introduced as diagnostic biomarker or drug design. The androgen receptor is one of the most important pathways involved in the pathogenesis of PCa. The miR-141, as a member of the miR-200 family has a regulatory role by targeting the Small heterodimer partner (SHP , NR0B2) at the downstream of this molecular pathway. Objective: The aim of this study was to investigate changes in the expression of miR-141 and SHP in tissue samples of PCa patients compared to benign prosttic hyperplasia (BPH) tissues. Method: In this study, changes in expression of miR-141 and SHP at the RNA level were performed using qRT-PCR technique on 68 prostate tissues containing, 26 localized PCa, 4 metastatic PCa, 30 BPH and 8 tumor-adjacent normal tissues. Also, the analysis of the results was investigated using REST software. Changes in SHP expression at protein level were investigated in 20 Paraffin-embedded tissue blocks containing 10 PCa and 10 BPH using immunohistochemistry (IHC). Results: The findings of this study showed that miR-141 increased in metastatic samples compared with localized samples (P <0.001, 31.17-fold change). Tumor samples showed a lower expression level of SHP compared with BPH tissues at mRNA and protein level (p = 0.014, 4.7 fold change) and (p = 0.02, 1.8 fold change), respectively. Conclusion: According to our results, it can be concluded that miR-141 plays a role in the pathogenesis of PCa through the androgen receptor signaling pathway and the SHP regulation. Also, miR-141 has a high potential for diagnosis of PCa as a prognostic biomarker. Keywords: Prostate cancer, SHP gene, miR-141, Biomarke

Disciplinary power, subjectivity and liberalism: a Foucauldian approach to the study of democracy and authoritarianism

In his work, Discipline and Punish: The Birth of the Prison, Michel Foucault enhances discipline from a simple and straightforward concept to one of the fundamental and constitutional elements of economic and political modernity. While Foucauldian scholars have dedicated a fair amount of research to explore the role of discipline in the advent of economic modernity, the role of discipline in the emergence of modern political forms in general and liberalism, in particular, has remained relatively undertheorized. In this thesis, I attempt to fill this lacuna by providing a Foucauldian account of the relationships between discipline and liberalism. I argue that discipline has contributed to the possibility of liberal politics by constructing self-governed political subjectivities. After analyzing the role that discipline has played in the emergence and success of liberal politics in Western societies, I examine the implications of this analysis for societies that are governed by authoritarian regimes. By taking Iran as a case study, I show how the failure of disciplinary projects in shaping self-governed political subjects has contributed to the persistence of authoritarianism in this country

Numerical investigation on the effects of single-mode microwave treatment on rock breakage system

[EN] In this study, a rock model which consists of a conceptual block (host rock and ore sample) is numerically modeled by using the finite element method. The rock model is subjected to several single-mode microwave treatments with different power levels, distances from the antenna, and exposure times in order to calculate and compare the corresponding effects including temperature distribution and mechanical stress/damage profiles. The main objective of the present study is to analyze the distribution of temperature and mechanical stress at the boundary of two different attached rocks when exposed to microwaves. This enables comparing the intensity of the distribution with respect to the applied microwave input operating parameters and, consequently, understanding rock preconditioning. The results of the present study verify that an increase in temperature by microwave treatment facilitates the rock weakening process. Also, a more efficient selection of the distance from the antenna and the power level can maximize the overall impact of the microwave treatment on rock preconditioning which ultimately helps with the rock breakage mechanism.Financial support for this work from the Natural Sciences and Engineering Research Council (NSERC) of Canada, the McGill Engineering Doctoral Award (MEDA) Award is gratefully acknowledged.Teimoori, K.; Hassani, F.; Sasmito, A.; Madiseh, A. (2019). Numerical investigation on the effects of single-mode microwave treatment on rock breakage system. En AMPERE 2019. 17th International Conference on Microwave and High Frequency Heating. Editorial Universitat Politècnica de València. 270-278. https://doi.org/10.4995/AMPERE2019.2019.9646OCS27027

Experimental Investigations of Microwave Effects on Rock Breakage Using SEM Analysis

[EN] Preconditioning of hard rocks by microwave energy has recently been considered a potentially effective technology in mechanical rock breakage for civil and mining engineering. To obtain the amount of mechanical damage that a single-mode microwave treatment produces in rocks, it is necessary to analyze and evaluate the thermal cracking process by microwave heating at different power levels, exposure times, and distances from the antenna. The current study employs the scanning electron microscopy imaging technique to capture images from surfaces of irradiated rock specimens and to compare them with a nontreated specimen. To evaluate and quantify the amount of cracking (i.e. crack density, crack size, etc.) in a rock specimen after microwave irradiation with different microwave input operating parameters, the following steps were evaluated. First, several experiments of single-mode microwave treatments with different operating parameters were performed on rectangular specimens of basalt. Then, cylindrical core samples with a dimension of r = 0.5 cm, h = 2cm, were drilled from the center of the irradiated specimens and prepared for image processing. The results of the present study show that there are significant differences between the number of microcracks present in samples irradiated at different power levels and distances from the antenna. Also, longer exposure times result in more severe cracks.Financial support for this work from the Natural Sciences and Engineering Research Council of Canada (NSERC), De Beers Group, Argex, Metso and the McGill Engineering Doctoral Award (MEDA) Award is gratefully acknowledged.Teimoori, K.; Hassani, F.; Sasmito, A.; Madiseh, A. (2019). Experimental Investigations of Microwave Effects on Rock Breakage Using SEM Analysis. En AMPERE 2019. 17th International Conference on Microwave and High Frequency Heating. Editorial Universitat Politècnica de València. 1-8. https://doi.org/10.4995/AMPERE2019.2019.96471

Delayed Graft Function

www.NUmonthly.co