Agreement Between Body Mass Index and Percent Body Fat in Resistance Trained Men and Women

National health organizations report on the prevalence of obesity utilizing statistics based upon Body Mass Index (BMI), a noninvasive, anthropometric measurement used for weight classification. Though the limitations of the BMI formula are well known, it is still commonly used in clinical settings due to the ease of calculation using only weight and height (kg/m2). Dual-Energy X-Ray Absorptiometry (DXA) is a criterion method for body composition estimation. PURPOSE: The purpose of this analysis was to assess the agreement between BMI classification and measured percent body fat (PBF) via DXA in a resistance-trained (RT) population. METHODS: DXA scans of resistance-trained male and female volunteers were included in this secondary analysis. Participants were divided into BMI classification and PBF levels as defined by the American College of Sports Medicine (ACSM). These categories were collapsed further into “obese” versus “not obese” cases according to BMI and then “obese” versus “not obese” cases according to PBF. Finally, agreement was measured using Chi-square goodness-of-fit. For analysis, BMI classification was used to determine the number of expected cases and PBF level was used to determine the number of observed cases. The analysis was repeated with categories collapsed into “overweight or obese” versus “not overweight or obese” cases for both BMI and PBF. RESULTS: Male (n = 237; age: 27.7 ± 10.7y; BMI: 29.6 ± 5.6; PBF: 20.9 ± 8.4%) and female (n=95; age: 25.2 ± 8.6y; BMI: 26.2 ± 5.6; PBF: 29.7 ± 8.3%) participants were distributed into collapsed BMI categories by sex and PBF categories by sex. Chi-square goodness-of-fit analysis revealed statistical significance between BMI and PBF in both obese versus not obese cases (males: χ2= 138.7, p\u3c.001; females: χ2 = 22.2, p\u3c.001) and overweight or obese versus not overweight or obese cases (males: χ2= 60, p\u3c.001; females: χ2 = 12.2; p\u3c.001). In males, BMI overestimated overweight and obese cases. Conversely, BMI underestimated overweight and obese cases in females. CONCLUSION: These data indicate that alternative methods for classification should be developed to accurately assess body composition of resistance-trained individuals. Moreover, because RT females classified in a normal weight category may be at risk for normal weight obesity, further emphasis should be placed upon increasing lean muscle mass in active females

Effects of eight weeks of an alleged aromatase inhibiting nutritional supplement 6-OXO (androst-4-ene-3,6,17-trione) on serum hormone profiles and clinical safety markers in resistance-trained, eugonadal males

The purpose of this study was to determine the effects of 6-OXO, a purported nutritional aromatase inhibitor, in a dose dependent manner on body composition, serum hormone levels, and clinical safety markers in resistance trained males. Sixteen males were supplemented with either 300 mg or 600 mg of 6-OXO in a double-blind manner for eight weeks. Blood and urine samples were obtained at weeks 0, 1, 3, 8, and 11 (after a 3-week washout period). Blood samples were analyzed for total testosterone (TT), free testosterone (FT), dihydrotestosterone (DHT), estradiol, estriol, estrone, SHBG, leutinizing hormone (LH), follicle stimulating hormone (FSH), growth hormone (GH), cortisol, FT/estradiol (T/E). Blood and urine were also analyzed for clinical chemistry markers. Data were analyzed with two-way MANOVA. For all of the serum hormones, there were no significant differences between groups (p > 0.05). Compared to baseline, free testosterone underwent overall increases of 90% for 300 mg 6-OXO and 84% for 600 mg, respectively (p < 0.05). DHT underwent significant overall increases (p < 0.05) of 192% and 265% with 300 mg and 600 mg, respectively. T/E increased 53% and 67% for 300 mg and 600 mg 6-OXO, respectively. For estrone, 300 mg produced an overall increase of 22%, whereas 600 mg caused a 52% increase (p < 0.05). Body composition did not change with supplementation (p > 0.05) and clinical safety markers were not adversely affected with ingestion of either supplement dose (p > 0.05). While neither of the 6-OXO dosages appears to have any negative effects on clinical chemistry markers, supplementation at a daily dosage of 300 mg and 600 mg for eight weeks did not completely inhibit aromatase activity, yet significantly increased FT, DHT, and T/E

The Impact of Differing Types of Physical Activity on Weight Loss, Strength, VO2 max, and the Various Metabolic Hormones.

PURPOSE: The purpose of this investigate the impact of differing types of physical activity on weight loss, strength, VO2 max, and various metabolic hormones. METHODS: Eleven sedentary and overweight male/females participated in this study and were randomly assigned to one of two exercise groups: aerobic training (A) (N = 4, 40 ± 8.7 yrs 165 ± 8.3cm, 89 ± 16 kg), or aerobic training plus resistance training (ART) (N = 7, 43 ± 10 yrs, 171 ± 8.7 cm, 91 ± 12 kg). Training protocols for the two exercise groups consisted of 30 min of aerobic exercise five days per week at 60-70% of heart rate max and 30 minutes of aerobic exercise three days per week at 60-70% of heart rate max plus two days of moderate intensity resistance exercise per week for the (A) and (ART) groups, respectively. Baseline testing consisted of weight, hip, and waist measurements, and body composition analysis using bioelectrical impedance. Participants donated approximately 20 ml of fasting blood for the analysis of clinical chemistry profiles, WBC counts, and the hormones insulin, leptin, and cortisol. Following these assessments, VO2 max, upper-body strength, and lower-body strength was established using standard procedures. All baseline assessments were repeated at 4 and 8 weeks of the study. Statistical analyses utilized a two-way ANOVA with repeated measures for all criterion variables (p\u3c0.05). RESULTS: A significant (p \u3c 0.05) increase in upper and lower body strength was observed in both A and ART groups, however there was no significant difference between groups. A significant group x time interaction (p \u3c 0.05) was observed for body weight (ART: -1.5 ± 0.3 lbs; A: 3 ± 0.5 lbs). No significant (p \u3e 0.05) main effects for group or time were observed for the criterion variables body fat, VO2 max, and the hormones insulin, leptin, and cortisol. Furthermore, neither protocol had a significant impact on body fat or VO2 max. CONCLUSIONS: It can be concluded that aerobic exercise coupled with resistance training for 8 weeks yielded greater results in weight loss than aerobic training alone. No marked changes were noted on the affects of any type of exercise regiment on body composition, VO2 max, or the hormones leptin, insulin, and cortisol over the 8-week study

The Effects of an Energy Increasing Supplement on Markers of V02 max, Body Composition, and Anaerobic Power

Research suggests that energy increasing supplement ingestion prior to prolonged aerobic exercise (\u3e60minutes) can improve aerobic capacity (VO2 Max). Energy increasing supplements affect on reduced aerobic training periods (\u3c60\u3eminutes) lack definitive empirical evidence. PURPOSE: To investigate the potential impact of an energy increasing supplement on aerobic training, body composition and anaerobic power. METHODS: Thirty-three healthy male and female subjects (18-30yrs) participated in an equated volume supervised running workout for six weeks utilizing long slow distance. Group one (N = 17, 21 ± 3 yr) participated in long slow distance training as a Placebo group void of any dietary instructions or interventions. Group two (N = 16, 21 ± 3 yr) participated in long slow distance training and was provided with a GU Energy Gel packet and 8 oz. of water fifteen minutes prior to the workout. All subjects participated in a familiarity session (FAM), a Pre-Test (T1) and a Post-Test (T2). Each testing session consisted of a V02 Max, a 30 second Wingate and body composition assessment. Data were analyzed by a two-way ANOVA with repeated measures. Significance was set at p \u3c 0.05 and adopted throughout. RESULTS: The GU and Placebo groups experienced significant increases (p \u3c 0.001), in VO2 max, with 9.71% (4.06 ± 2.68 ml/kg/min) and 2.81% (1.26 ± 2.25 ml/kg/min) increases respectively. A significant interaction (p \u3c 0.005) in VO2 max occurred between groups, as the GU group displayed a 322% greater increase when compared to the Placebo group. Body fat percentage significantly decreased (p \u3c 0.05) in the GU (0.76 ± 2.47%) and Placebo (1.55 ± 3.21%) groups without a significant reduction in total body weight at a p \u3c 0.05 significant level. No change was observed in Wingate peak or mean power (p \u3c 0.05). CONCLUSION: The findings of this study suggest GU Energy Gel supplementation has a more profound impact on aerobic capacity when compared to a Placebo under identical training protocols. However, both GU Energy Gel and Placebo supplementation had a significant effect on aerobic capacity and body fat percentage

EFFECTS OF A PROPRIETARY BLEND RICH IN GLYCOSIDE BASED STANDARDIZED FENUGREEK SEED EXTRACT (IBPR) ON INFLAMMATORY MARKERS DURING ACUTE ECCENTRIC RESISTANCE EXERCISE IN YOUNG SUBJECTS

  Objective: To assess the efficacy of a proprietary blend rich in glycoside based standardized fenugreek seed extract (400 mg) and minor quantities of curcumin and cinnamon (25 mg each) supplementation (IBPR) on inflammatory markers related to skeletal muscle soreness using double-blind placebo control, parallel design.Methods: A total of 20 healthy non-resistance trained young male and female subjects were assigned to ingest either IBPR or matching placebo for 14 days before the eccentric exercise bout. Subjects were instructed to perform 24 sets with 10 eccentric knee extensor repetitions (with one leg at 30°/s on an isokinetic device). Subjects had their blood drawn at baseline, immediately post, 1 hr, 3 hrs, and 24 hrs post-eccentric exercise. Efficacy in terms of serum levels of anti-inflammatory cytokines interleukin-10 (IL-10), pro-inflammatory cytokines (IL-1ra, IL-1b, IL-6, and tumor necrosis factor) and safety in terms of kidney function (blood urea nitrogen (BUN), serum creatinine, BUN to creatinine ratio), and differential leukocyte count were measured. The data of each parameter were analyzed by two-way repeated measure ANOVA.Results: Significant time-dependent effects were observed in IL1b, IL6, and creatinine values from baseline whereas significant treatment dependent effect was seen in IL-1ra. IBPR was found to be safe and well tolerated.Conclusion: IBPR supplementation showed a significant anti-inflammatory efficacy on eccentric exercise-induced inflammatory markers of skeletal muscle soreness in non-resistance trained subjects

The effects of a commercially available botanical supplement on strength, body composition, power output, and hormonal profiles in resistance-trained males

<p>Abstract</p> <p>Background</p> <p>Fenugreek (<it>Trigonella foenum-graecum</it>) is a leguminous, annual plant originating in India and North Africa. In recent years Fenugreek has been touted as an ergogenic aid. The purpose of this study was to evaluate the effects of Fenugreek supplementation on strength and body composition.</p> <p>Methods</p> <p>49 Resistance trained men were matched according to body weight and randomly assigned to ingest in a double blind manner capsules containing 500 mg of a placebo (N = 23, 20 ± 1.9 years, 178 ± 6.3 cm, 85 ± 12.7 kg, 17 ± 5.6 %BF) or Fenugreek (N = 26, 21 ± 2.8 years, 178 ± 6 cm, 90 ± 18.2 kg, 19.3 ± 8.4 %BF). Subjects participated in a supervised 4-day per week periodized resistance-training program split into two upper and two lower extremity workouts per week for a total of 8-weeks. At 0, 4, and 8-weeks, subjects underwent hydrodensiometery body composition, 1-RM strength, muscle endurance, and anaerobic capacity testing. Data were analyzed using repeated measures ANOVA and are presented as mean ± SD changes from baseline after 60-days.</p> <p>Results</p> <p>No significant differences (p > 0.05) between groups were noted for training volume. Significant group × time interaction effects were observed among groups in changes in body fat (FEN: -2.3 ± 1.4%BF; PL: -0.39 ± 1.6 %BF, p < 0.001), leg press 1-RM (FEN: 84.6 ± 36.2 kg; PL: 48 ± 29.5 kg, p < 0.001), and bench press 1-RM (FEN: 9.1 ± 6.9 kg; PL: 4.3 ± 5.6 kg, p = 0.01). No significant interactions was observed among groups for Wingate power analysis (p = 0.95) or muscular endurance on bench press (p = 0.87) or leg press (p = 0.61). In addition, there were no changes among groups in any clinical safety data including lipid panel, liver function, kidney function, and/or CBC panel (p > 0.05).</p> <p>Conclusion</p> <p>It is concluded that 500 mg of this proprietary Fenugreek extraction had a significant impact on both upper- and lower-body strength and body composition in comparison to placebo in a double blind controlled trial. These changes were obtained with no clinical side effects.</p