10 research outputs found

    A thick photoresist process for advanced wafer level packaging applications using JSR THB-151N negative tone UV photoresist

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    10.1088/0960-1317/16/9/012Journal of Micromechanics and Microengineering1691841-1846JMMI

    Bed of nails: Fine pitch wafer-level packaging interconnects for high performance nano devices

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    Proceedings of 7th Electronics Packaging Technology Conference, EPTC 20052658-66

    Bed of Nails - 100 microns pitch wafer level interconnections process

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    Proceedings of 6th Electronics Packaging Technology Conference, EPTC 2004444-44

    Ensuring good quality rna for quantitative real-time pcr isolated from renal proximal tubular cells using laser capture microdissection

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    10.1186/1756-0500-7-62BMC Research Notes716

    A novel test strategy for fine pitch wafer-level packaged devices

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    10.1109/TADVP.2007.898617IEEE Transactions on Advanced Packaging303439-447ITAP

    On the use of fuzzy inference systems for assessment and decision making problems

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    The Fuzzy Inference System (FIS) is a popular paradigm for undertaking assessment/measurement and decision problems. In practical applications, it is important to ensure the monotonicity property between the attributes (inputs) and the measuring index (output) of an FIS-based assessment/ measurement model. In this chapter, the sufficient conditions for an FIS-based model to satisfy the monotonicity property are first investigated. Then, an FIS-based Risk Priority Number (RPN) model for Failure Mode and Effect Analysis (FMEA) is examined. Specifically, an FMEA framework with a monotonicity-preserving FIS-based RPN model that fulfils the sufficient conditions is proposed. A case study pertaining to the use of the proposed FMEA framework in the semiconductor industry is presented. The results obtained are discussed and analyzed

    CISH and susceptibility to infectious diseases.

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    BACKGROUND: The interleukin-2-mediated immune response is critical for host defense against infectious pathogens. Cytokine-inducible SRC homology 2 (SH2) domain protein (CISH), a suppressor of cytokine signaling, controls interleukin-2 signaling. METHODS: Using a case-control design, we tested for an association between CISH polymorphisms and susceptibility to major infectious diseases (bacteremia, tuberculosis, and severe malaria) in blood samples from 8402 persons in Gambia, Hong Kong, Kenya, Malawi, and Vietnam. We had previously tested 20 other immune-related genes in one or more of these sample collections. RESULTS: We observed associations between variant alleles of multiple CISH polymorphisms and increased susceptibility to each infectious disease in each of the study populations. When all five single-nucleotide polymorphisms (SNPs) (at positions -639, -292, -163, +1320, and +3415 [all relative to CISH]) within the CISH-associated locus were considered together in a multiple-SNP score, we found an association between CISH genetic variants and susceptibility to bacteremia, malaria, and tuberculosis (P=3.8x10(-11) for all comparisons), with -292 accounting for most of the association signal (P=4.58x10(-7)). Peripheral-blood mononuclear cells obtained from adult subjects carrying the -292 variant, as compared with wild-type cells, showed a muted response to the stimulation of interleukin-2 production--that is, 25 to 40% less CISH expression. CONCLUSIONS: Variants of CISH are associated with susceptibility to diseases caused by diverse infectious pathogens, suggesting that negative regulators of cytokine signaling have a role in immunity against various infectious diseases. The overall risk of one of these infectious diseases was increased by at least 18% among persons carrying the variant CISH alleles
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