Clinical effects of platelet-rich fibrin (PRF) following surgical extraction of lower third molar

Objective: The purpose of this study was to assess the effect of platelet-rich fibrin (PRF) on postoperative pain, analgesic consumption, soft tissue healing and socket complications following the extraction of mandibular third molars. Methods: A total number of 50 impacted third molars were surgically removed from 47 patients (13 males and 34 females; with a mean age of 25.24 ± 7.04 years). PRF clots were placed in the extraction sockets of patients included in the study group, while the sockets remained empty in the control group. The variables assessed were pain, analgesic consumption, soft tissue healing and socket complications encountered during the first postoperative week. Results: In the study group, a significantly less pain was recorded in the fifth, sixth and seventh postoperative days (P = 0.041, 0.031 and 0.005 respectively). Patients included in the study group also significantly consumed less analgesics for the second, third, sixth and seventh postoperative days (P = 0.019, 0.039, 0.045 and 0.020 respectively). PRF significantly reduced the incidence of alveolar osteitis (P = 0.037) but not the infected or inflamed sockets (P = 1.00 and 0.312 respectively). No significant difference was observed between PRF and control groups regarding soft tissue healing (P = 0.187). Conclusion: PRF could reduce alveolar osteitis, pain, and analgesic consumption following removal of impacted mandibular third molars

Efficacy of nano-hydroxyapatite coating on osseointegration of early loaded dental implants

Background and Objectives:  The success rates of dental implants have been reported as a challenge, especially for early loading in the posterior maxilla area. The surfaces of dental implants are generally modified in an attempt to improve osseointegration. In which Unitite implants with Nano hydroxyapatite coating affect the healing process acceleration, high hydrophilicity, increased bone formation (BIC - Bone Implant Contact ), and the quality improvement of the new bone formed (BAFO - Bone Area Fraction Occupancy), keeping the original implant microtopography. This study aimed to evaluate the efficacy of Nano hydroxyapatite coating osseointegration of early loaded dental implants in the posterior maxilla. Patients and Methods: A clinical trial was carried out on ten patients need  twelve  implants with early loading   were treated in the oral and Maxillofacial Surgery Department, Faculty of Dentistry, Mansoura University ;  A root-form implant is the most frequently used type of dental implant today. The basis for dental implants is osseointegration, the HAnano® coating associated with its microtopography generate an increase in the titanium surface energy, making the implant highly hydrophilic, which guarantees the presence of blood and its components in the healing chamber