Probing mu-term Generation Mechanism in String Models

We give a generic method to select a realistic $\mu$-term generation mechanism based on the radiative electroweak symmetry breaking scenario and study which type is hopeful within the framework of string theory. We discuss effects of the moduli F-term condensation and D-term contribution to soft scalar masses.Comment: Latex, 17 pages, 4 Postscript figure

Combination chemotherapy with anticancer agents and OK-432

Antitumor effects of the combination chemotherapy with hemolytic streptococcus preparation, OK-432, and various anticancer agents were observed on experimental tumors and human cancers. Experimental studies revealed that combined use of OK-432 with Mitomycin C, Nitrogen mustard N-Oxide or Bleomycin was remarkably effective on rodent transplantable tumors such as Ehrlich carcinoma, sarcoma-lOO and rat ascitic hepatoma AH-66. As for the mode of action of OK-432, besides a direct action on cancer cells, a host-mediated action appears to be also involved. Clinical trials were made on 14 cases with various advanced cancers, and favorable response was obtained in 5 with lung cancer. Fever was the major side effect of OK-432 and there was no evidence of bone marrow suppression.</p

Studies on the host-mediated action of the streptococcal preparation, OK-432, in cancer chemotherapy

The streptococcal preparation, OK.432, with predominant host-mediated mode of action, was studied. By giving OK-432 to mice intraperitoneally prior to transplantation of Ehrlich carcinoma, a host-mediated action to increase life-span was clearly confirmed. Pretreatment with OK-432 was also effective against the development of Rauscher leukemia. The host-mediated action of OK-432 varied with the interval between its pretreatment and the inoculation of tumor cells. The effect was most marked when the transplant was performed immediatedly after the pretreatment, and became less marked when the transplant was made one week and two weeks after pretreatment. The host-mediated action can be observed even with a single dose of pretreatment, and becomes more potent as pretreatment was given repeatedly. The host-mediated action was weakened by concomitant pretreatment with cyclophosphamide or roentgen irradiation, and the mechanisms of such action was supposed to be associated with the function of the reticulo-endothelial system.</p

Frustration and relaxation of antiferromagnetic domains reversed by magneto-electric field cooling in a Pt/Co/Au/Cr₂O₃/Pt-stacked film

Using magnetic domain observations, we investigated the reversal process of the perpendicular exchange bias polarity resulting from the antiferromagnetic Cr₂O₃ domain reversal driven by magneto-electric field cooling (MEFC). The exchange bias polarity changed from negative to positive with increasing electric field during MEFC. The relevant change in the magnetic domain revealed the stochastic appearance of the reversed magnetic domains that exhibit the positive exchange bias. The local magnetization curves suggest that the antiferromagnetic domain state after MEFC was frustrated because of energy competition between the interfacial exchange coupling and the bulk magneto-electric effect. The frustrated nature of the magnetic domain structure is supported by the training effect of the exchange bias after MEFC.Yu Shiratsuchi, Shunsuke Watanabe, Shogo Yonemura, Tatsuo Shibata, and Ryoichi Nakatani, AIP Advances 8, 125313 (2018); https://doi.org/10.1063/1.5053136

Clinical Experience Using a Real Time Autofluorescence Endoscopy System in the Gastrointestinal Tract

Autofluorescence spectra of neoplastic tissues have been reported to be significantly different from those of normal tissues when excited by blue or violet light. From this concept, a light-induced autofluorescence endoscopic imaging system for gastrointestinal mucosa (LIFE-GI; Xillix, Canada and Olympus, Japan) has been newly developed and the clinical evaluation of the prototype system has been conducted in hospitals in Canada, Netherlands and Japan