3 research outputs found

    A legalização do aborto na Argentina: proteção dos direitos das mulheres, meninas e pessoas que gestam

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    A luta pela legalização do aborto enquanto direito das mulheres e demais pessoas que gestam é parte da luta por direitos sexuais e reprodutivos e tem como principais articuladores os movimentos feministas. No sul global, observamos um descompasso no que se refere à garantia desse direito. Países com realidades parecidas e que vivenciaram a retomada dos movimentos de mulheres na última década não tiveram o mesmo êxito e, por vezes, sofreram retrocessos. Diferente do Brasil, por exemplo, a Argentina viveu uma importante vitória em 2020, a lei de interrupção voluntária da gravidez. A partir dos resultados parciais da pesquisa intitulada “As legalidades e ilegalidades do direito ao aborto na América Latina e Caribe”, que atualmente vem se aprofundando na análise da exitosa experiência argentina da legalização do direito ao aborto, objetivamos discutir alguns elementos que ajudem a desvelar quais foram as forças e argumentos recorridos na luta por esse direito, expressados por vezes nas lutas dos movimentos supracitados, bem como obter um panorama da legislação outrora conservadora e a atual, que considera a diversidade de mulheres, meninas e pessoas que gestam naquele país

    Physico-chemical characterization and antibacterial activity of inclusion complexes of Hyptis martiusii Benth essential oil in β-cyclodextrin

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    Bezerra, Daniel Pereira. Fundação Gonçalo Moniz. Centro de Pesquisas Gonçalo Moniz. Salvador, BA, Brasil. a Pharmacy Department, Federal University of Sergipe, Sergipe, Brazil b Department of Biological Chemistry, Regional University of Cariri, Crato, Ceará, Brazil c Physiology Department, Federal University of Sergipe, Sergipe, Brazil d Gonçalo Muniz Research Center, Oswaldo Cruz Foundation, Bahia, Brazil e Department of Mineralogy and Geotectonics, Institute of Geosciences, University of SãoPaulo-SP, BrazilSubmitted by Ana Maria Fiscina Sampaio ([email protected]) on 2018-04-23T13:36:40Z No. of bitstreams: 1 Andrade TA Physico-chemical....pdf: 3585852 bytes, checksum: 8a7e1bcbe17cb62a62c347459f8804ba (MD5)Approved for entry into archive by Ana Maria Fiscina Sampaio ([email protected]) on 2018-04-23T13:48:34Z (GMT) No. of bitstreams: 1 Andrade TA Physico-chemical....pdf: 3585852 bytes, checksum: 8a7e1bcbe17cb62a62c347459f8804ba (MD5)Made available in DSpace on 2018-04-23T13:48:34Z (GMT). No. of bitstreams: 1 Andrade TA Physico-chemical....pdf: 3585852 bytes, checksum: 8a7e1bcbe17cb62a62c347459f8804ba (MD5) Previous issue date: 2017Conselho Nacional de Desenvolvimento Científico e Tecnológico/CNPq/Brazil and Fundação de Amparo à Pesquisa do Estado de Sergipe/FAPITEC-SE.Múltipla – ver em NotasCyclodextrins (CDs) have been used as important pharmaceutical excipients for improve the physicochemical properties of the drugs of low solubility as the essential oil of Hyptis martiusii. This oil is important therapeutically, but the low solubility and bioavailability compromises your use. Therein, the aim of this study was to obtain and to characterize physico-chemically the samples obtained by physical mixture (PM), paste complexation (PC) and slurry complexation (SC) of the essential oil Hyptis martiusii (EOHM) in β-CD, and to compare the antibacterial and modulatory-antibiotic activity of products obtained and oil free. The physicochemical characterization was performed by differential scanning calorimetry (DSC), thermogravimetry/derivative thermogravimetry (TG/DTG), scanning electron microscopy (SEM), X-ray diffraction (XRD) and Karl Fischer titration. Additionally, the antibacterial tests were performed by microdilution technique. Thus, it was observed that the PM method showed low complexing capacity, unlike PC and SC in which it was observed the formation of inclusion complexes. In addition, the second stage of the TG/DTG curves showed that SC was the best method inclusion with mass loss of 6.9% over the PC that was 6.0%. The XRD results corroborate with the results above suggesting the formation of new solid phase and the SEM photomicrographs showed the porous surface of the samples PC and SC. The essential oil alone demonstrated an antibacterial and modulatory effect against the S. aureus and the Gram negative strain, respectively. However, the β-CD and the inclusion complex did not demonstrate any biological activity in the performed antibacterial assays
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