The Portrayal of Child Soldiers in Documentaries and Hollywood Film

People in the United States are becoming increasingly mindful of child soldiers, with film being a critical means of bringing about awareness. However, awareness can be dependent upon media representation since most individuals in the U.S. do not have direct experiences with child soldiers. The purpose of the present study is to discover how the media has portrayed child soldiers in Hollywood films and documentaries, with an emphasis on the portrayal of violence, the role of women, and the reintegration experiences of child soldiers that are shown. Through a combined qualitative and quantitative content analysis, this study explores the depictions of young children in armed forces as a way to better understand society’s perception of child soldiers. Five Hollywood films and five documentaries were selected at random from an initial pool and viewed by two coders. The coders discovered that while women were portrayed more often than expected, the unique challenges faced by female child soldiers were not represented with great accuracy. Reintegration was depicted in most films; documentaries were more likely to focus on long-term reintegration and Hollywood films were more likely to focus on short-term reintegration. Hollywood films were also more likely than documentaries to portray violent action and show changes in the attitudes and emotions among the child soldiers over time

Microdensitometric analysis of denervation effects on newt limb blastema cells

This report examines the fate of cycling cells in normal and denervated blastemas of adult newts. Cells are found to accumulate in G 1 in blastemas which are nerve independent. No stage specific accumulation different from controls is found in limbs with nerve-dependent blastemas.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/42735/1/18_2005_Article_BF01971783.pd

Different Requirement for Wnt/β-Catenin Signaling in Limb Regeneration of Larval and Adult Xenopus

BACKGROUND:In limb regeneration of amphibians, the early steps leading to blastema formation are critical for the success of regeneration, and the initiation of regeneration in an adult limb requires the presence of nerves. Xenopus laevis tadpoles can completely regenerate an amputated limb at the early limb bud stage, and the metamorphosed young adult also regenerates a limb by a nerve-dependent process that results in a spike-like structure. Blockage of Wnt/β-catenin signaling inhibits the initiation of tadpole limb regeneration, but it remains unclear whether limb regeneration in young adults also requires Wnt/β-catenin signaling. METHODOLOGY/PRINCIPAL FINDINGS:We expressed heat-shock-inducible (hs) Dkk1, a Wnt antagonist, in transgenic Xenopus to block Wnt/β-catenin signaling during forelimb regeneration in young adults. hsDkk1 did not inhibit limb regeneration in any of the young adult frogs, though it suppressed Wnt-dependent expression of genes (fgf-8 and cyclin D1). When nerve supply to the limbs was partially removed, however, hsDkk1 expression blocked limb regeneration in young adult frogs. Conversely, activation of Wnt/β-catenin signaling by a GSK-3 inhibitor rescued failure of limb-spike regeneration in young adult frogs after total removal of nerve supply. CONCLUSIONS/SIGNIFICANCE:In contrast to its essential role in tadpole limb regeneration, our results suggest that Wnt/β-catenin signaling is not absolutely essential for limb regeneration in young adults. The different requirement for Wnt/β-catenin signaling in tadpoles and young adults appears to be due to the projection of nerve axons into the limb field. Our observations suggest that nerve-derived signals and Wnt/β-catenin signaling have redundant roles in the initiation of limb regeneration. Our results demonstrate for the first time the different mechanisms of limb regeneration initiation in limb buds (tadpoles) and developed limbs (young adults) with reference to nerve-derived signals and Wnt/β-catenin signaling