5 research outputs found

    Π˜Π½Ρ‚Π΅Ρ€Ρ„Π΅Ρ€ΠΎΠ½ΠΎΠ²Ρ‹ΠΉ статус Ρƒ ΠΆΠ΅Π½Ρ‰ΠΈΠ½ с Ρ€Π΅Ρ†ΠΈΠ΄ΠΈΠ²ΠΈΡ€ΡƒΡŽΡ‰ΠΈΠΌ Π³Π΅Π½ΠΈΡ‚Π°Π»ΡŒΠ½Ρ‹ΠΌ гСрпСсом ΠΏΡ€ΠΈ ΠΊΠΎΠΌΠ±ΠΈΠ½ΠΈΡ€ΠΎΠ²Π°Π½Π½ΠΎΠΉ Ρ‚Π΅Ρ€Π°ΠΏΠΈΠΈ ΠΏΡ€Π΅ΠΏΠ°Ρ€Π°Ρ‚ΠΎΠΌ липосомальной РНК

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    The aim of this study was the estimation of the influence of liposomal ribonucleic acid (RNA) medicine Β«LiprinaΒ» on interferon status of women with recurrent genital herpes. In this study 60 women were included, who combined (acyclovir and Liprina, nΒ =Β 40) or monoterapy with acyclovir (nΒ =Β 20) were received. The levels of serum interferon alpha and gamma along with cervical virus elimination were estimated. The medicine Β«LiprinaΒ» increased the therapy efficiency of the women with genital herpes, that perhaps related with endogen interferon production amplification.ΠŸΡ€ΠΎΠ²Π΅Π΄Π΅Π½Π° ΠΎΡ†Π΅Π½ΠΊΠ° влияния ΠΏΡ€Π΅ΠΏΠ°Ρ€Π°Ρ‚Π° липосомальной Ρ€ΠΈΠ±ΠΎΠ½ΡƒΠΊΠ»Π΅ΠΈΠ½ΠΎΠ²ΠΎΠΉ кислоты (РНК) Β«Π›ΠΈΠΏΡ€ΠΈΠ½Π°Β» Π½Π° ΠΈΠ½Ρ‚Π΅Ρ€Ρ„Π΅Ρ€ΠΎΠ½ΠΎΠ²Ρ‹ΠΉ статус Ρƒ ΠΆΠ΅Π½Ρ‰ΠΈΠ½ с Ρ€Π΅Ρ†ΠΈΠ΄ΠΈΠ²ΠΈΡ€ΡƒΡŽΡ‰ΠΈΠΌ Π³Π΅Π½ΠΈΡ‚Π°Π»ΡŒΠ½Ρ‹ΠΌ гСрпСсом. Π‘Ρ‹Π»ΠΎ обслСдовано 60 ΠΆΠ΅Π½Ρ‰ΠΈΠ½, ΠΈΠ· ΠΊΠΎΡ‚ΠΎΡ€Ρ‹Ρ… 40 ΠΏΠΎΠ»ΡƒΡ‡Π°Π»ΠΈ ΠΊΠΎΠΌΠ±ΠΈΠ½ΠΈΡ€ΠΎΠ²Π°Π½Π½ΡƒΡŽ Ρ‚Π΅Ρ€Π°ΠΏΠΈΡŽ (Π°Ρ†ΠΈΠΊΠ»ΠΎΠ²ΠΈΡ€ ΠΈ Π»ΠΈΠΏΡ€ΠΈΠ½Π°) ΠΈ 20 β€” ΠΌΠΎΠ½ΠΎΡ‚Π΅Ρ€Π°ΠΏΠΈΡŽ Π°Ρ†ΠΈΠΊΠ»ΠΎΠ²ΠΈΡ€ΠΎΠΌ. Π˜Π·ΡƒΡ‡Π΅Π½ΠΎ ΠΈΠ·ΠΌΠ΅Π½Π΅Π½ΠΈΠ΅ сывороточных ΡƒΡ€ΠΎΠ²Π½Π΅ΠΉ ΠΈΠ½Ρ‚Π΅Ρ€Ρ„Π΅Ρ€ΠΎΠ½ΠΎΠ²-Ξ± ΠΈ -Ξ³ наряду с элиминациСй вируса ΠΈΠ· Ρ†Π΅Ρ€Π²ΠΈΠΊΠ°Π»ΡŒΠ½ΠΎΠ³ΠΎ ΠΊΠ°Π½Π°Π»Π°. Показано, Ρ‡Ρ‚ΠΎ ΠΏΡ€Π΅ΠΏΠ°Ρ€Π°Ρ‚ Β«Π›ΠΈΠΏΡ€ΠΈΠ½Π°Β» ΠΏΠΎΠ²Ρ‹ΡˆΠ°Π΅Ρ‚ ΡΡ„Ρ„Π΅ΠΊΡ‚ΠΈΠ²Π½ΠΎΡΡ‚ΡŒ Ρ‚Π΅Ρ€Π°ΠΏΠΈΠΈ ΠΏΡ€ΠΈ Π³Π΅Π½ΠΈΡ‚Π°Π»ΡŒΠ½ΠΎΠΌ гСрпСсС, Ρ‡Ρ‚ΠΎ, Π²ΠΎΠ·ΠΌΠΎΠΆΠ½ΠΎ, связано с усилСниСм Π²Ρ‹Ρ€Π°Π±ΠΎΡ‚ΠΊΠΈ эндогСнных ΠΈΠ½Ρ‚Π΅Ρ€Ρ„Π΅Ρ€ΠΎΠ½ΠΎΠ²

    Interferon status at the women with recurrent genital herpes in combined liposomal RNA treatment

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    The aim of this study was the estimation of the influence of liposomal ribonucleic acid (RNA) medicine Β«LiprinaΒ» on interferon status of women with recurrent genital herpes. In this study 60 women were included, who combined (acyclovir and Liprina, nΒ =Β 40) or monoterapy with acyclovir (nΒ =Β 20) were received. The levels of serum interferon alpha and gamma along with cervical virus elimination were estimated. The medicine Β«LiprinaΒ» increased the therapy efficiency of the women with genital herpes, that perhaps related with endogen interferon production amplification

    Small Molecule Adenosine 5β€²-Monophosphate Activated Protein Kinase (AMPK) Modulators and Human Diseases

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