Non-Spinning Black Holes in Alternative Theories of Gravity

We study two large classes of alternative theories, modifying the action through algebraic, quadratic curvature invariants coupled to scalar fields. We find one class that admits solutions that solve the vacuum Einstein equations and another that does not. In the latter, we find a deformation to the Schwarzschild metric that solves the modified field equations in the small coupling approximation. We calculate the event horizon shift, the innermost stable circular orbit shift, and corrections to gravitational waves, mapping them to the parametrized post-Einsteinian framework.Comment: 7 pages, submitted to PR

Dynamics of a deformable self-propelled particle under external forcing

We investigate dynamics of a self-propelled deformable particle under external field in two dimensions based on the model equations for the center of mass and a tensor variable characterizing deformations. We consider two kinds of external force. One is a gravitational-like force which enters additively in the time-evolution equation for the center of mass. The other is an electric-like force supposing that a dipole moment is induced in the particle. This force is added to the equation for the deformation tensor. It is shown that a rich variety of dynamics appears by changing the strength of the forces and the migration velocity of self-propelled particle

Viral Vector Malaria Vaccines Induce High-Level T Cell and Antibody Responses in West African Children and Infants.

Heterologous prime-boosting with viral vectors encoding the pre-erythrocytic antigen thrombospondin-related adhesion protein fused to a multiple epitope string (ME-TRAP) induces CD8+ T cell-mediated immunity to malaria sporozoite challenge in European malaria-naive and Kenyan semi-immune adults. This approach has yet to be evaluated in children and infants. We assessed this vaccine strategy among 138 Gambian and Burkinabe children in four cohorts: 2- to 6-year olds in The Gambia, 5- to 17-month-olds in Burkina Faso, and 5- to 12-month-olds and 10-week-olds in The Gambia. We assessed induction of cellular immunity, taking into account the distinctive hematological status of young infants, and characterized the antibody response to vaccination. T cell responses peaked 7 days after boosting with modified vaccinia virus Ankara (MVA), with highest responses in infants aged 10 weeks at priming. Incorporating lymphocyte count into the calculation of T cell responses facilitated a more physiologically relevant comparison of cellular immunity across different age groups. Both CD8+ and CD4+ T cells secreted cytokines. Induced antibodies were up to 20-fold higher in all groups compared with Gambian and United Kingdom (UK) adults, with comparable or higher avidity. This immunization regimen elicited strong immune responses, particularly in young infants, supporting future evaluation of efficacy in this key target age group for a malaria vaccine

Higher gametocyte production and mosquito infectivity in chronic compared to incident Plasmodium falciparum infections.

Plasmodium falciparum gametocyte kinetics and infectivity may differ between chronic and incident infections. In the current study, we assess parasite kinetics and infectivity to mosquitoes among children (aged 5-10 years) from Burkina Faso with (a) incident infections following parasite clearance (n = 48) and (b) chronic asymptomatic infections (n = 60). In the incident infection cohort, 92% (44/48) of children develop symptoms within 35 days, compared to 23% (14/60) in the chronic cohort. All individuals with chronic infection carried gametocytes or developed them during follow-up, whereas only 35% (17/48) in the incident cohort produce gametocytes before becoming symptomatic and receiving treatment. Parasite multiplication rate (PMR) and the relative abundance of ap2-g and gexp-5 transcripts are positively associated with gametocyte production. Antibody responses are higher and PMR lower in chronic infections. The presence of symptoms and sexual stage immune responses are associated with reductions in gametocyte infectivity to mosquitoes. We observe that most incident infections require treatment before the density of mature gametocytes is sufficient to infect mosquitoes. In contrast, chronic, asymptomatic infections represent a significant source of mosquito infections. Our observations support the notion that malaria transmission reduction may be expedited by enhanced case management, involving both symptom-screening and infection detection

Geodesic flows on real forms of complex semi-simple Lie groups of rigid body type

The geodesic flows are studied on real forms of complex semi-simple Lie groups with respect to a left-invariant (pseudo-)Riemannian metric of rigid body type. The Williamson types of the isolated relative equilibria on generic adjoint orbits are determined

The U(n) free rigid body rigid body: Integrability and stability analysis of the equilibria

A natural extension of the free rigid body dynamics to the unitary group U(n) is considered. The dynamics is described by the Euler equation on the Lie algebra u(n), which has a bi-Hamiltonian structure, and it can be reduced onto the adjoint orbits, as in the case of the SO(n). The complete integrability and the stability of the isolated equilibria on the generic orbits are considered by using the method of Bolsinov and Oshemkov. In particular, it is shown that all the isolated equilibria on generic orbits are Lyapunov stable

Some local questions for hyperbolic systems with non-regular time dependent coefficients

International audienceIn this note we investigate local properties for microlocally symmetrizable hyperbolic systems with just time dependent coefficients. Thanks to Paley-Wiener theorem, we establish finite propagation speed by showing precise estimates on the evolution of the support of the solution in terms of suitable norms of the coefficients of the operator and of the symmetrizer. From this result, local existence and uniqueness follow by quite standard methods. Our argument relies on the use of Fourier transform, and it cannot be extended to operators whose coefficients depend also on the space variables. On the other hand, it works under very mild regularity assumptions on the coefficients of the operator and of the symmetrizer