Additional file 2: Table S1. of Effect of propofol on microRNA expression in rat primary embryonic neural stem cells

Gene list based on different search strategies. A total of 420 different genes that related to propofol exposure were selected when duplicates were excluded and their expression data were downloaded from the GEO Profiles. (XLSX 27 kb

Impacts of the “transport subsidy initiative on poor TB patients” in Rural China: A Patient-Cohort Based Longitudinal Study in Rural China

<div><p>Objective</p><p>To describe the financial burden on TB patients for transportation during treatment, and to evaluate the impacts of the “transportation subsidy initiative on poor TB patients” in rural China for improving poor patients’ access to TB treatment.</p> <p>Methods</p><p>A Case-cohort of 429 TB patients was investigated through questionnaire interviews in four counties of two provinces in China. Information on the financial burden for transportation during TB diagnosis and treatment was collected. Qualitative in-depth interviews with 26 TB patients were carried out to understand their perceptions of transportation subsidy initiative.</p> <p>Results</p><p>The mean transportation cost of TB medical care was 97 CNY (70 CNY in median), varying from 0 to 700 CNY. About 51% of the patients spent more than 10 CNY per round trip to the TB dispensary. Of the 429 TB patients investigated, 139 had received transportation subsidies after getting TB diagnosis; 15/139 (10.9%) showed dissatisfaction, mainly because the subsidy amount being insufficient. The income of patients receiving transportation subsidies was significantly lower than those not receiving the subsidies (<i>p</i><0.05). The impression that an appropriate transportation subsidy enables patients to complete the required visits during their TB treatment was obtained after observation of over 80% of the patients.</p> <p>Conclusion</p><p>The transportation subsidy plays an important role in reducing financial burden on poor TB patients for the completion of treatment. However, the coverage was limited and the amount of subsidy was not enough under the present policy. Considering the poverty of rural TB patients, a universal coverage and a rational amount of transportation subsidy should be proposed.</p> </div

Additional file 4: Table S4. of Effect of propofol on microRNA expression in rat primary embryonic neural stem cells

Predicted miRs of validated genes. By searching the four databases (miRWalk, miRanda, miRDB and TargetScan), 248 and 346 miRNAs were predicted to target the 3′ UTRs of EGR2 and ARC, respectively. (XLSX 42 kb

Additional file 1: of Comparison of glycemic control and β-cell function in new onset T2DM patients with PCOS of metformin and saxagliptin monotherapy or combination treatment

Flow diagram of participants. Chart showing the number of participants who were randomly assigned, those who received the intended treatment, and those who were analyzed for the primary outcome. (EPS 1314 kb

Additional file 2: Table S1. of Effect of propofol on microRNA expression in rat primary embryonic neural stem cells

Gene list based on different search strategies. A total of 420 different genes that related to propofol exposure were selected when duplicates were excluded and their expression data were downloaded from the GEO Profiles. (XLSX 27 kb

Assessment of urine CCL2 as a potential diagnostic biomarker for acute kidney injury and septic acute kidney injury in intensive care unit patients

Acute kidney injury (AKI) is a prevalent and serious condition in the intensive care unit (ICU), associated with significant morbidity and mortality. Septic acute kidney injury (SAKI) contributes substantially to AKI cases in the ICU. However, current diagnostic methods have limitations, necessitating the exploration of novel biomarkers. In this study, we investigated the potential of plasma and urine CCL2 levels as diagnostic markers for AKI and SAKI in 216 ICU patients. Our findings revealed significant differences in plasma (p p p p p < 0.0001). These results suggest that urine CCL2 levels hold promise as early biomarkers for AKI and SAKI, offering valuable insights for timely intervention and improved management of ICU patients.</p

Proportion of TB patients spending less than 10CNY on transportation

<p>Proportion of TB patients spending less than 10CNY on transportation</p

Additional file 3: Table S2. of Effect of propofol on microRNA expression in rat primary embryonic neural stem cells

GO_BP of the different expressive genes. The genes were predicted to be involved in 124 biological functions. (XLSX 34 kb

Tuning the Spectroscopic, Electrochemical, and Single-Crystal Conductance Properties of a Series of Rhenium-Containing Bithiazoles with Different Donor/Acceptor Hybrids

The first Re­(I)–bithiazole complexes are structurally reported. Complexes with the general formula <i>fac</i>-[ReL­(CO)₃Cl] have been designed and prepared successfully, where the bidentate chelating ligand L is one of a family of linear bithiazole based aromatic heterocyclic fluorescent compounds bearing different donor/acceptor tails (proton, bromo, thienyl, dibenzo­[<i>b</i>,<i>d</i>]­thienyl, phenylcarbazolyl, and triphenylamino). X-ray single-crystal structures of five <i>fac</i>-[ReL­(CO)₃Cl] complexes indicate that the bithiazole cores have the same cis coplanar configuration, while the trans configuration can only be observed in the free ligands. Furthermore, density functional theory computational studies on different molecular conformations as well as spectral, electrochemical, and solid-state conductance properties for related compounds before and after the metal ion complexation have been carried out for full comparisons

Tuning the Spectroscopic, Electrochemical, and Single-Crystal Conductance Properties of a Series of Rhenium-Containing Bithiazoles with Different Donor/Acceptor Hybrids

The first Re­(I)–bithiazole complexes are structurally reported. Complexes with the general formula <i>fac</i>-[ReL­(CO)₃Cl] have been designed and prepared successfully, where the bidentate chelating ligand L is one of a family of linear bithiazole based aromatic heterocyclic fluorescent compounds bearing different donor/acceptor tails (proton, bromo, thienyl, dibenzo­[<i>b</i>,<i>d</i>]­thienyl, phenylcarbazolyl, and triphenylamino). X-ray single-crystal structures of five <i>fac</i>-[ReL­(CO)₃Cl] complexes indicate that the bithiazole cores have the same cis coplanar configuration, while the trans configuration can only be observed in the free ligands. Furthermore, density functional theory computational studies on different molecular conformations as well as spectral, electrochemical, and solid-state conductance properties for related compounds before and after the metal ion complexation have been carried out for full comparisons