Design and development of a multi-functional laparoscopic device

This study presents a design of a multifunctional laparoscopic appendectomy device that includes three surgical instruments commonly used in laparoscopic appendicitis surgeries: endoloop, endobag and scissors. It collects these three independent surgical tools in a single laparoscopic appendectomy device. These days there is a trend of moving to multi-functional surgery devices during minimally invasive surgery. The main reasons behind the minimal invasive surgery are to avoid changing the devices several times during the operation, to reduce the time spent in operation, to increase the efficiency of the operation, to facilitate the follow-up of the camera and devices, and to leave trocars to be used for other surgical instruments. The multi-functional appendectomy device that, we present here, provides these benefits. The standard trocar entries are appropriate for its usage. The presented multifunctional laparoscopic appendectomy device offers more practical use in comparison to individual devices. On the other hand, development of these multi-functional surgery devices can be directly enhanced to the robotic surgery devices

Comparison of a modified anoscope and the purse-string anoscope in stapled haemorrhoidopexy

AIM: To compare the results of the anoscope of the PPH kit and a modified anoscope during stapled haemorrhoidopexy

A Retrospective Study of 39 Patients Treated With Anterior Approach of Thoracic and Lumbar Spondylodiscitis Clinical Manifestations, Anterior Surgical Treatment, and Outcome

The aim of this study is to report our 39 patients treated with anterior debridement and autologous iliac bone grafting with or without anterior instrumentation, which is the presumed treatment of choice for thoracic or lumbar spondylodiscitis.Our patients underwent surgical treatment of spondylodiscitis using anterior debridement and autologous iliac bone grafting with or without anterior instrumentation and were analyzed with a mean follow-up of 8 years (range, 2-11 years). Kaneda 2-rod system instrumentation was used in 12 patients, in total. Clinical outcomes were assessed by the Frankel grade. Radiographic fusion was characterized based on 3-dimensional computed tomography.Of the whole group, 20 patients suffered from tuberculous spondylodiscitis and 19 suffered from hematogenous spondylodiscitis. Pathogens responsible for pyogenic infection included Staphylococcus aureus (4 patients), Pseudomonas aeruginosa (3 patients), and Brucella melitensis (1 patient). Fifteen patients had thoracic involvement, 20 had lumbar involvement, and 4 had thoracolumbar junction involvement. Preoperative neurological deficits were noted in 13 of the 39 patients. In terms of Frankel grade, 8 patients have improved, 4 have remained the same, and 1 patient has worsened during the follow-up period. Imaging-documented fusion was achieved in 23 of 27 patients in the graft group (85% fusion rate) and 11 of 12 patients in the graft+Kaneda instrumentation group (91% fusion rate).There was no instrumentation failure, loosening, or graft-related complication such as slippage or fracture of the graft. This approach demonstrated a good recovery rate of neurological functions and a high fusion rate

Effect of Sildenafil on the Skeletal Muscle Regeneration: An Experimental Study

Objective: Sildenafil is a phosphodiesterase 5 (PDE5) inhibitor that induces vasodilatation and is currently used in treatment of erectile dysfunction and pulmonary hypertension. The aim of this study was to investigate the effects of sildenafil on the regenerative activity of skeletal muscle adjacent to the abdominal wall wound in rats. Material and Methods: This study was conducted in Aegean University Faculty of Medicine Animal Research Laboratory between July 2008 and August 2008, and was performed with adult female Wistar-Albino rats. A control group (n= 50) was fed on a standard laboratory diet until 12 h before surgery. The study group (n= 50) was administered sildenafil therapy (10 mg/kg once a day for 10 days) through an orogastric tube. Each rat was anesthetized, and a 4-cm-long midline laparotomy was performed. Ten animals from each group were killed at postoperative days (PODs) 4, 7, 14, 21, and 35. The abdominal incision wounds and surrounding tissues were examined histologically. Results: Regenerative capacity of the abdominal muscle in sildenafil treatment group was significantly higher than the control group and the difference was statistically significant (p <= 0.01). Conclusion: This study showed that sildenafil augmented the regenerative activity of the skeletal muscle. If this result can be reproduced by other studies, sildenafil may be beneficial therapy for degenerative muscle diseases

Effect of sildenafil on wound healing: an experimental study

We aimed to investigate the effect of sildenafil on the healing process of abdominal wall wound in rats