Results from RHIC with Implications for LHC

Results from the PHENIX experiment at RHIC in p-p and Au+Au collisions are reviewed from the perspective of measurements in p-p collisions at the CERN-ISR which serve as a basis for many of the techniques used. Issues such as J/Psi suppression and hydrodynamical flow in A+A collisions require data from LHC-Ions for an improved understanding. Suppression of high pT particles in Au+Au collisions, first observed at RHIC, also has unresolved mysteries such as the equality of the suppression of inclusive pi0 (from light quarks and gluons) and direct-single electrons (from the decay of heavy quarks) in the transverse momentum range 4< pT < 9 GeV/c. This disfavors a radiative explanation of suppression and leads to a fundamental question of whether the Higgs boson gives mass to fermions. Observation of an exponential distribution of direct photons in central Au+Au collisions for 1< pT <2 GeV/c where hard-processes are negligible and with no similar exponential distribution in p-p collisions indicates thermal photon emission from the medium at RHIC, making PHENIX at the moment ``the hottest experiment in Physics''.Comment: Invited lectures at the International School of Subnuclear Physics, 47th Course, "The most unexpected at LHC and the status of High Energy Frontier'', Erice, Sicily, Italy, August 29-September 7. 2009. 32 pages, 22 figure

Debye screening in strongly coupled N=4 supersymmetric Yang-Mills plasma

Using the AdS/CFT correspondence, we examine the behavior of correlators of Polyakov loops and other operators in N=4 supersymmetric Yang-Mills theory at non-zero temperature. The implications for Debye screening in this strongly coupled non-Abelian plasma, and comparisons with available results for thermal QCD, are discussed.Comment: 21 pages, 5 figures, significantly expanded discussion of Polyakov loop correlator and static quark-antiquark potentia

A fundamental test of the Higgs Yukawa coupling at RHIC in A+A collisions

Searches for the intermediate boson, $W^{\pm}$, the heavy quantum of the Weak Interaction, via its semi-leptonic decay, $W\to e +\nu$, in the 1970's instead discovered unexpectedly large hadron production at high $p_T$, notably $\pi^0$, which provided a huge background of $e^{\pm}$ from internal and external conversions. Methods developed at the CERN ISR which led to the discovery of direct-single-$e^{\pm}$ in 1974, later determined to be from the semi-leptonic decay of charm which had not yet been discovered, were used by PHENIX at RHIC to make precision measurements of heavy quark production in p-p and Au+Au collisions, leading to the puzzle of apparent equal suppression of light and heavy quarks in the QGP. If the Higgs mechanism gives mass to gauge bosons but not to fermions, then a proposal that all 6 quarks are nearly massless in a QGP, which would resolve the puzzle, can not be excluded. This proposal can be tested with future measurements of heavy quark correlations in A+A collisionsComment: 12 pages, 16 figures, 26th Winter Workshop on Nuclear Dynamics, Ocho Rios, Jamaica WI, January 2-9, 2010. Corrected citation of 1974 direct single lepton discover

Serum Metabolomics in a Helicobacter hepaticus Mouse Model of Inflammatory Bowel Disease Reveal Important Changes in the Microbiome, Serum Peptides, and Intermediary Metabolism

Inflammatory bowel disease (IBD) is a chronic relapsing inflammatory disorder of the bowel. The etiology remains unknown, but IBD is immune-driven and multiple factors including genetic, environmental, and microbiological components play a role. Recombinase-activating gene-2-deficient (Rag2–/–) mice infected with Helicobacter hepaticus (H. hepaticus) have been developed as an animal model to imitate naturally occurring inflammatory events and associated key features of chronic inflammatory responses in humans. In this study, we have combined mass spectrometry-based metabolomics and peptidomics to analyze serum samples of Rag2–/– mice infected with H. hepaticus. Metabolomics profiling revealed that H. hepaticus infection dramatically changed numerous metabolite pathways, including tryptophan metabolism, glycerophospholipids, methionine-homocysteine cycle, citrate cycle, fatty acid metabolism and purine metabolism, with the majority of metabolites being down-regulated. In particular, there were notable effects of gut microflora on the blood metabolites in infected animals. In addition, the peptidomics approach identified a number of peptides, originating from proteins, including fibrinogen, complement C4, and alpha-2-macroglobulin, with diverse biological functions with potentially important implications for the progress of IBD. In summary, the strategy of integrating a relevant animal model and sensitive mass spectrometry-based profiling may offer a new perspective to explore biomarkers and provide mechanistic insights into IBD.National Institute of Environmental Health Sciences (MIT Center for Environmental Health Sciences, NIEHS grant (Grant No. ES002109))Massachusetts Institute of Technology (MIT-Merck Fellowship

Hadronic centrality dependence in nuclear collisions

The kaon number density in nucleus+nucleus and p+p reactions is investigated for the first time as a function of the initial energy density $\epsilon$ and is found to exhibit a discontinuity around $\epsilon$=1.3 GeV/fm$^3$. This suggests a higher degree of chemical equilibrium for $\epsilon >$ 1.3 GeV/fm$^3$. It can also be interpreted as reflection of the same discontinuity, appearing in the chemical freeze out temperature (T) as a function of $\epsilon$. The $N^{\alpha \sim 1}$ dependence of (u,d,s) hadrons, whith N the number of participating nucleons, also indicates a high degree of chemical equilibrium and T saturation, reached at $\epsilon >$1.3 GeV/fm$^3$. Assuming that the intermediate mass region (IMR) dimuon enhancement seen by NA50 is due to open charm ($D \bar{D}$), the following observation can be made: a) Charm is not equilibrated. b) $J/\Psi/D \bar{D}$ suppression -unlike $J/\Psi/DY$- appears also in S+A collisions, above $\epsilon$ $\sim$1 GeV/fm$^3$. c) Both charm and strangeness show a discontinuity near the same $\epsilon$. d) $J/\Psi$ could be formed mainly through $c \bar{c}$ coalescence. e) The enhancement factors of hadrons with u,d,s,c quarks may be connected in a simple way to the mass gain of these particles if they are produced out of a quark gluon plasma (QGP). We discuss these results as possible evidence for the QCD phase transition occuring near $\epsilon \sim$1.3 GeV/fm$^3$.Comment: 4 pages, 4 figures, proceedings of Vth International Conference on Strangeness in Quark Matter, 20-25 July 2000, Berkeley, California. To appear in Journal of Physics G: Nuclear and Particle Physic