80 research outputs found
Role of Human Factors in Fall from Height Fatalities in the UK Construction Industry
Globally, fall from heights remains incessant in the construction industry with recent statistics revealing that about 65% of fatalities are directly linked to fall from height in the UK construction industry. Moreover, the problem is exacerbated by the persistent and reoccurring nature of falls from height in the construction industry. Yet, research about the contemporary roles of human factors vis-Ã -vis falls from height across high-risk industries is scarce.
Aim:
The study aims to provide a robust analysis regarding the role of human factors in fatalities caused by falls from height in the UK construction industry. Research question: What is the relationship between human factors and persistent falls from height incidents in the construction industry?
Method:
Mixed research methods (Qual-Quan) concept and phenomenological research strategy were adopted for a better understanding of the research variables. The study relied on HSE archived data and data obtained through a response to a Freedom of Information (FOI) request sent to the Health and Safety Executive (HSE) UK for 10 years data on fall accidents in the UK construction industry. Also, a semi-structured interview was conducted with professionals in high-risk industries for better insight into the study.
Result:
The initial findings of the research show a range of human contributory factors such as workers fatigue, mental slips, hastiness, organisational pressures, etc are responsible for persistent falls among workers.
Conclusion:
The study findings reveal that 75% of falls from height cases in the UK construction industry are caused by human factors and it further underscores the significant role human factors play in falls from height incidents. Other findings from the study suggest that the use of bespoke and modernised airbag PPE by construction workers has the potential to significantly mitigate the effects of falls from height. The study is part of an ongoing PhD research that seeks to develop a conceptual framework aimed at managing dysfunctional safety practices among workers in the UK’s high-risk industries
Theories of Costs of Health and Safety Compliance and Non-Compliance with Regulations
Globally, the economics of health and safety compliance and non-compliance with regulations remains absurd and elusive. Costs of health and safety compliance at enterprise level are elements that organisations find difficult to define or price adequately due to subtle, inconspicuous, and elusive nature. Conversely, evidence shows that costs of health and safety non-compliance with regulations in recent times are eye-watering and mind-boggling. Yet, theory that provides explanation of cost behaviours concerning health and safety compliance and non-compliance with regulations is rare.
Aim: The aim of the study is to develop a theoretical concept that can be used to predict costs of health and safety non-compliance with regulations.
Research question: put forward by the paper is: What are the predictable cost behaviours of health and safety compliance and non-compliance with regulations?
Research Method: Phenomenological research strategy was adopted; with qualitative data collected via focus group discussions; in addition to detailed observation of 20 years real costs of health and safety non-compliance with regulations data.
Findings: Reveal that costs of health and safety compliance with regulations are often ill-defined and elusive. Similarly, the study discovered that cost behaviour of health and safety non-compliance with regulations can be erratic and exponential in nature. Other finding reveals that for every health and safety failure (ill-health, injuries/fatalities), there are likely associated costs, that are contingent on specific legislations, rule of law, state (national laws), and commercial viability of organisation involved
Free breathing contrast-enhanced time-resolved magnetic resonance angiography in pediatric and adult congenital heart disease
Contrast enhanced magnetic resonance angiography (MRA) is generally performed during a long breath-hold (BH), limiting its utility in infants and small children. This study proposes a free-breathing (FB) time resolved MRA (TRA) technique for use in pediatric and adult congenital heart disease (CHD)
Pre-Operative Grade of Decompressing Systemic Venous Collaterals, But Not Jugular Venous Pressure, Predicts Short- and Medium-Term Outcome After Completion of the Total Cavopulmonary Connection
Utility of adenosine stress perfusion CMR to assess paediatric coronary artery disease
AIMS: Cardiovascular magnetic resonance (CMR), using adenosine stress perfusion and late-gadolinium enhancement (LGE), is becoming the 'gold standard' non-invasive imaging modality in the assessment of adults with coronary artery disease (CAD). However, despite its proved feasibility in paediatric patients, clinical utility has not been demonstrated. Therefore, this study aims to establish the role of adenosine stress perfusion CMR as a screening test in paediatric patients with acquired or congenital CAD. METHODS AND RESULTS: A total of 58 paediatric patients underwent 61 consecutive clinically indicated coronary artery assessments for diagnostic and clinical decision-making purposes. The diagnosis was based on X-ray or computed tomography coronary angiography for anatomy, adenosine stress CMR imaging for myocardial perfusion and LGE for tissue characterization. Two studies were aborted because of unwanted side effects of adenosine stress, thus 59 studies were completed in 56 patients [median age 14.1 years (interquartile range 10.9-16.2)]. When compared with coronary anatomical imaging, adenosine stress perfusion CMR performed as follows: sensitivity 100% (95% confidence interval, CI: 71.6-100%), specificity 98% (95% CI: 86.7-99.9%), positive predictive value (PPV) 92.9% (95% CI: 64.2-99.6%), and negative predictive value 100% (95% CI: 89.9-100%). CONCLUSION: In paediatric CAD, adenosine stress perfusion CMR imaging is adequate as an initial, non-invasive screening test for the identification of significant coronary artery lesions, with anatomical imaging used to confirm the extent of the culprit lesion
Real-time assessment of right and left ventricular volumes and function in children using high spatiotemporal resolution spiral bSSFP with compressed sensing
Background:
Real-time cardiovascular magnetic resonance (CMR) assessment of ventricular volumes and function enables data acquisition during free-breathing. The requirement for high spatiotemporal resolution in children necessitates the use of highly accelerated imaging techniques.
Methods:
A novel real-time balanced steady state free precession (bSSFP) spiral sequence reconstructed using Compressed Sensing (CS) was prospectively validated against the breath-hold clinical standard for assessment of ventricular volumes in 60 children with congenital heart disease. Qualitative image scoring, quantitative image quality, as well as evaluation of biventricular volumes was performed. Standard BH and real-time measures were compared using the paired t-test and agreement for volumetric measures were evaluated using Bland Altman analysis.
Results:
Acquisition time for the entire short axis stack (~ 13 slices) using the spiral real-time technique was ~ 20 s, compared to ~ 348 s for the standard breath hold technique. Qualitative scores reflected more residual aliasing artefact (p < 0.001) and lower edge definition (p < 0.001) in spiral real-time images than standard breath hold images, with lower quantitative edge sharpness and estimates of image contrast (p < 0.001).
There was a small but statistically significant (p < 0.05) overestimation of left ventricular (LV) end-systolic volume (1.0 ± 3.5 mL), and underestimation of LV end-diastolic volume (− 1.7 ± 4.6 mL), LV stroke volume (− 2.6 ± 4.8 mL) and LV ejection fraction (− 1.5 ± 3.0%) using the real-time technique. We also observed a small underestimation of right ventricular stroke volume (− 1.8 ± 4.9 mL) and ejection fraction (− 1.4 ± 3.7%) using the real-time imaging technique. No difference in inter-observer or intra-observer variability were observed between the BH and real-time sequences.
Conclusions:
Real-time bSSFP imaging using spiral trajectories combined with a compressed sensing reconstruction showed good agreement for quantification of biventricular metrics in children with heart disease, despite slightly lower image quality. This technique holds the potential for free breathing data acquisition, with significantly shorter scan times in children
Estimation of Radiation Dosimetry for 68Ga-HBED-CC (PSMA-11) in Patients with Suspected Recurrence of Prostate Cancer
Introduction
This study was performed to estimate the human radiation dosimetry for [68Ga]Ga-HBED-CC (PSMA-11) (68Ga PSMA-11).
Methods
Under an RDRC-approved research protocol, we evaluated the biodistribution and pharmacokinetics of 68Ga PSMA-11 with serial PET imaging following intravenous administration to nine prostate cancer patients in whom clinical [11C]acetate PET/CT exams had been independently performed under Expanded Access IND 118,204. List-mode imaging was performed over the initial 0–10 min post-injection with the pelvis in the field-of-view. Whole-body images were acquired, pelvis-to-head, at 15, 60, and 90-min post-injection. Additional images of the pelvis were acquired at 40-min and 115-min, and voided urine collected from each subject at 48-min and 120-min post-injection. Radiation dosimetry estimates were calculated from these data using the OLINDA software package.
Results
Renal uptake was high and relatively invariant, ranging from 11% to 14% of the injected dose between 15 and 90-min post-injection. Radioactivity collected in the voided urine accounted for 14% of the injected dose over a period of 120-min. Lymph nodes and skeletal metastases suspicious for prostate cancer recurrence were detected in a greater number of patients using 68Ga PSMA-11 than using 11C-acetate.
Conclusion
Kidneys are the critical organ following 68Ga PSMA-11 administration, receiving an estimated dose of 0.413 mGy/MBq.
Advances in knowledge and implications for patient care
This study confirms that the kidneys will be the critical organ following intravenous administration of 68Ga PSMA-11, and provided data consistent with the expectation that 68Ga PSMA-11 will be superior to [11C]acetate for defining sites of recurrence in prostate cancer patients presenting with biochemical relapse
Update of the European Association of Cardiovascular Imaging (EACVI) Core Syllabus for the European Cardiovascular Magnetic Resonance Certification Exam
An updated version of the European Association of Cardiovascular Imaging (EACVI) Core Syllabus for the European Cardiovascular Magnetic Resonance (CMR) Certification Exam is now available online. The syllabus lists key elements of knowledge in CMR. It represents a framework for the development of training curricula and provides expected knowledge-based learning outcomes to the CMR trainees, in particular those intending to demonstrate CMR knowledge in the European CMR exam, a core requirement in the CMR certification process
Early cranial ultrasound findings among infants with neonatal encephalopathy in Uganda: an observational study.
BACKGROUND: In sub-Saharan Africa, the timing and nature of brain injury and their relation to mortality in neonatal encephalopathy (NE) are unknown. We evaluated cranial ultrasound (cUS) scans from term Ugandan infants with and without NE for evidence of brain injury. METHODS: Infants were recruited from a national referral hospital in Kampala. Cases (184) had NE and controls (100) were systematically selected unaffected term infants. All had cUS scans <36 h reported blind to NE status. RESULTS: Scans were performed at median age 11.5 (interquartile range (IQR): 5.2-20.2) and 8.4 (IQR: 3.6-13.5) hours, in cases and controls respectively. None had established antepartum injury. Major evolving injury was reported in 21.2% of the cases vs. 1.0% controls (P < 0.001). White matter injury was not significantly associated with bacteremia in encephalopathic infants (odds ratios (OR): 3.06 (95% confidence interval (CI): 0.98-9.60). Major cUS abnormality significantly increased the risk of neonatal death (case fatality 53.9% with brain injury vs. 25.9% without; OR: 3.34 (95% CI: 1.61-6.95)). CONCLUSION: In this low-resource setting, there was no evidence of established antepartum insult, but a high proportion of encephalopathic infants had evidence of major recent and evolving brain injury on early cUS imaging, suggesting prolonged or severe acute exposure to hypoxia-ischemia (HI). Early abnormalities were a significant predictor of death
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